CAS: 14077-58-8; 2-Ethoxyacetyl Chloride

相似化合物

21062-20-4 38870-89-2 16024-55-8

上下游产品

CAS号627-03-2 乙氧基乙酸 | CAS号60-29-7 乙醚 | CAS号101-83-7 二环己胺 | CAS号98-88-4 苯甲酰氯 | CAS号17952-11-3 戊基乙基醚 | CAS号30492-56-9 三乙基膦酰乙酸酯 | CAS号817-95-8 乙氧基乙酸乙酯 | CAS号628-32-0 乙丙醚 | CAS号76086-05-0 1-ethoxybutan-2-one | CAS号101-81-5 二苯甲烷 | CAS号30086-84-1 N-(4-Benzoyl-2-... | CAS号88422-80-4 2-ethoxy-N-(2-p... | CAS号92115-42-9 butyl 2-ethoxya... | CAS号579-94-2 孟格立酯

乙氧基乙酸置于草酰氯体系中,用 二氯甲烷 用作溶剂,化学反应生成乙氧基乙酰氯
参考文献:通过α-重氮-β-酮基酯的分子内ch催化催化不对称诱导的立体选择性合成二取代的3(2H)-呋喃酮
标题:通过α-重氮-β-酮基酯的分子内ch催化催化不对称诱导的立体选择性合成二取代的3(2H)-呋喃酮
摘要:铑(II)催化的γ-烷氧基-α-重氮-β-酮酸酯的分解产生具有高(> 97%)立体选择性的顺式-2,5-二取代-3(2H)-呋喃酮.重氮前体的酯部分中的手性助剂和手性催化剂的组合可导致不对称合成,其非对映选择性高达61%de.
Doi:10.1016/0040-4039(94)85379-7

专利信息

专利号:RU-2026293-C1
优先权日:1989-08-10
标 题 :Method of synthesis of imidazole derivative

专利号:US-4288444-A
优先权日:1976-06-21
标题 :Analgesic and morphine-antagonistic 6,7-benzomorphans
发明人：AKKERMAN ANTONY M; VAN BAKEL HERMANUS C C K; VAN BREEVOORT-UURBANUS HENRIET
权利人:ACF CHEMIEFARMA NV
摘要:The invention is concerned with certain new 6,7-benzomorphan derivatives having pharmacological, in particular analgesic and/or morphine-antagonistic properties, of the formula wherein R1 is a substituted or unsubstituted phenyl or heteroaryl group; R2 is a hydrogen or halogen atom, or a hydroxy, alkoxy or acyloxy group; R3 is an alkyl or alkenyl group; R4 is a hydrogen atom or a hydroxy, alkoxy or acyloxy group; and R5 is an alkyl group or, when R2 is hydrogen in a trans-position to R3, R5 is a hydrogen atom or an alkyl, alkenyl, alkinyl, cycloalkyl, cycloalkylalkyl, cycloalkenylalkyl, cyanoalkyl, hydroxyalkyl, alkoxyalkyl, or a substituted or unsubstituted phenylalkyl, heteroarylalkyl or heterocycloalkylalkyl group; optical isomers and pharmaceutically acceptable salts thereof. The preferred compound is the alpha -isomer of 2,5-dimethyl-2'-hydroxy-9-phenyl-6,7-benzomorphan, in particular its (+)-enantiomer. These compounds are prepared by total synthesis and are not derived from opium alkaloids.

专利号:CN-1951898-A
优先权日:2006-09-29
标 题:A kind of chemical synthesis method of acetoxyacetyl chloride