CAS: 13476-25-0; (10S,10As,E)-5,9-Dimethyl-3,6,10,10A-Tetrahydro-2H-10,1A-(Epoxymethano)Oxireno[2',3':4,5]Cyclodeca[1,2-B]Furan-12-One

该化合物是自然产生的松树类化合物,主要来自某些植物物种,特别是林德林的植物,其特点是复杂的双环结构,有助于其独特的化学特性.林德龙以其潜在的生物活动而著称,包括抗微生物和抗炎影响,使其对药理学研究感兴趣.该化合物通常在基本油类中发现,有独特的芳香,其来源可能不同.其溶解性特征受其缺水性的影响,往往使其在有机溶剂中比在水中更容易溶解.此外,林德龙的稳定性可能受到光和温度等环境因素的影响,这些因素可能导致降解或转化成其他化合物.总的来说,林德兰是天然产品化学中一个令人着迷的研究领域,对医药化学和自然香化合物的发展都有影响.

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    优先权日:2021-09-10
    标 题:Application of benzyl isoquinoline alkaloid and derivative thereof in synthesis of gene Ac6OMT

    专利号:CN-114891840-A
    优先权日:2022-05-23
    标 题 :Application of lotus leaf O-methyltransferase and its encoding gene in the synthesis of benzylisoquinoline alkaloids and phenylpropionic acids

    专利号:CN-116478941-A
    优先权日:2023-02-27
    标 题:Application of CYP80G protein and its coding gene in catalyzing the synthesis of aporphine alkaloids in lotus leaf

    专利号:CN-114891840-B
    优先权日:2022-05-23
    标题:Lotus leaf O-methyltransferase and application of encoding gene thereof in synthesis of benzyl isoquinoline alkaloid and phenylpropionic acid compounds

    专利号:CN-114874139-B
    优先权日:2022-05-27
    标 题:Synthesis method of 1-benzyl or allyl 3, 4-dihydroisoquinoline

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    主要参考文献


    1: Wang H, Wang K, Mao X, Zhang Q, Yao T, Peng Y, Zheng J. Mechanism-based inactivation of CYP2C9 by linderane. Xenobiotica. 2015;45(12):1037-46. doi: 10.3109/00498254.2015.1041002. Epub 2015 Jun 11. doi: 10.1016/j.fitote.2016.03.020. Epub 2016 Apr 2. Chinese. doi: 10.1021/np900354q. Chinese. doi: 10.3389/fphar.2018.00476. eCollection 2018.
    7: Wu Y, Zheng Y, Liu X, Han Z, Ren Y, Gan L, Zhou C, Luan L. Separation and quantitative determination of sesquiterpene lactones in Lindera aggregata (wu-yao) by ultra-performance LC-MS/MS. J Sep Sci. 2010 Apr;33(8):1072-8. doi: 10.1002/jssc.200900768. doi: 10.1016/j.jep.2016.12.025. Epub 2016 Dec 15. pii: E1792. doi: 10.3390/molecules23071792.

    合成参考文献


    参考文献:10.1002/jccs.199500073
    摘要:Wu S, Li W. Chemical Constituents from the Roots of Neolitsea hiiranensis. J Chinese Chemical Soc. 1995 Jun;42(3):555–60. doi: 10.1002/jccs.199500073.
    参考文献:10.1021/np9602269
    摘要:Chen K, Chang F, Jong T, Wu Y. Two Novel Sesquiterpenes from Neolitsea parvigemma. J. Nat. Prod. 1996 Jan 01;59(7):704–6. doi: 10.1021/np9602269.
    参考文献:10.1016/0031-9422(93)85167-p
    摘要:Wen-Shyong L, Chang-Yih D. Sesquiterpene lactones from Neolitsea villosa. Phytochemistry. 1993;32(6):1503–7. doi: 10.1016/0031-9422(93)85167-p.
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