CAS: 75-60-5; Dimethylarsinic Acid

上下游产品

CAS号124-58-3 甲基胂酸 | CAS号13787-40-1 sodium dimethyl... | CAS号593-88-4 三甲基胂 | CAS号557-89-1 chlorodimethylarsine | CAS号55094-22-9 dimethylarsinou... | CAS号471-35-2 tetramethyldiarsine | CAS号503-80-0 dimethylarsanyl... | CAS号593-57-7 dimethylarsine | CAS号10102-44-0 二氧化氮 | CAS号5814-20-0 四甲基碘化砷 | CAS号609-99-4 3,5-二硝基水杨酸 | CAS号15132-04-4 dimethylarsinate | CAS号676-75-5 二甲基碘 | CAS号7732-18-5 水 | CAS号7553-56-2 碘 | CAS号69819-89-2 6,8-bis[(dimeth... | CAS号1077-28-7 硫辛酸 | CAS号124-58-3 甲基胂酸 | CAS号75-93-4 methyl hydrogen...

专利信息

专利号:US-2023235372-A1
优先权日:2020-06-12
标题:Ab-initio, template-independent synthesis of nucleic acids using thermostable enzymes
发明人：RANDRIANJATOVO-GBALOU IRINA; SAID AHMED; RAHIER RENAUD
权利人:SYNHELIX
摘要:The invention relates to the field of nucleic acid synthesis or sequencing, more specifically to methods for ab-initio synthesis of nucleic acids, comprising contacting a nucleotide with a free 3′-hydroxyl group, with at least one nucleoside triphosphate, or a combination of nucleoside triphosphates, in the presence of an archaeal DNA primase or a functionally active fragment and/or variant thereof, thereby covalently binding said nucleoside triphosphate to the free 3′-hydroxyl group of the nucleotide. It also relates to isolated functionally active fragments of archaeal DNA primases which are capable of both ab-initio single-stranded nucleic acid synthesis activity and template-independent terminal nucleotidyl transferase activity.

专利号:US-2023313255-A1
优先权日:2020-07-15
标题:Massively Parallel Enzymatic Synthesis of Polynucleotides
发明人：HORGAN ADRIAN; LACHAIZE HENRI; VERARDO DOMIANO; GODRON XAVIER
权利人:DNA SCRIPT
摘要:The invention is directed to methods and compositions for inkjet assisted synthesis of a plurality of polynucleotides at reaction sites on a substrate using template-free polymerases, such as, terminal deoxynucleotidyl transferases (TdTs). Compositions of the invention include formulations of synthesis reagents for inkjet delivery including, but not limited to, TdT coupling reaction buffers and 3′-O-protected dNTP monomers.

专利号:US-2023235373-A1
优先权日:2020-06-12
标 题:Controlled template-independent synthesis of nucleic acids using thermostable enzymes
发明人：RANDRIANJATOVO-GBALOU IRINA; SAID AHMED; RAHIER RENAUD
权利人:SYNHELIX
摘要:The invention relates to methods for template-independent synthesis of nucleic acids, comprising iteratively contacting an initiator sequence comprising a 3′-end nucleotide with a free 3′-hydroxyl group, with at least one nucleoside triphosphate, or a combination of nucleoside triphosphates, in the presence of an archaeal DNA primase or a functionally active fragment and/or variant thereof, thereby covalently binding said nucleoside triphosphate to the free 3-hydroxyl group of the 3-end nucleotide. It also relates to isolated functionally active fragments of archaeal DNA primases which are capable of template-independent terminal nucleotidyl transferase activity but are devoid of a template-independent primase activity.

专利号:US-2024052391-A1
优先权日:2020-10-29
标 题 :Enzymatic Synthesis of Polynucleotide Probes
发明人：GODRON XAVIER; NIYOMCHON SUPAPORN; CHAMPION ELISE
权利人:DNA SCRIPT
摘要:The present invention is directed to methods and kits for enzymatic synthesis of labeled polynucleotide probes using template-free DNA polymerases.

专利号:US-2022411840-A1
优先权日:2019-11-13
标题 :High Efficiency Template-Free Enzymatic Synthesis of Polynucleotides
发明人：CHAMPION ELISE; SOSKINE MIKHAEL; SUNE ELODIE; YBERT THOMAS; GODRON XAVIER; HEINISCH TILLMANN
权利人:DNA SCRIPT
摘要:The invention is directed to compositions and methods for enzymatic template-free synthesis of polynucleotides wherein different terminal deoxynucleotidyl transferase (TdT) variants are used to incorporate different 3′-O-reversibly blocked deoxynucleoside triphosphates (dNTPs) into a growing chain. In part, the invention is a recognition and appreciation that different TdT variants can be engineered to preferentially incorporate specific dNTPs with higher efficiency than a single “general purposeâ€? TdT variant used to incorporate all four 3-O-reversibly blocked dNTPs.

专利号:US-2023062303-A1
优先权日:2019-12-12
标题 :Chimeric Terminal Deoxynucleotidyl Transferases For Template-Free Enzymatic Synthesis Of Polynucleotides
发明人：CHAMPION ELISE; SOSKINE MIKHAEL; JAZIRI FATEN; MCHALE DANIEL
权利人:DNA SCRIPT
摘要:The invention is directed to compositions and methods for enzymatic template-free synthesis of polynucleotides using terminal deoxynucleotidyl transferases that are chimeras derived from variants from different species.