CAS: 527-09-3; Copper(Ii) (2R,3S,4R,5R)-2,3,4,5,6-Pentahydroxyhexanoate

相似化合物

6485-39-8 526-95-4 96154-36-8

专利信息

专利号:WO-2009018504-A1
优先权日:2007-08-01
标题 :Process for the synthesis of diaminopyridine and related compounds
发明人：RITTER JOACHIM C
权利人:DU PONT; RITTER JOACHIM C
摘要:A process is provided for the synthesis of a diaminopyridine, such as 2,6-diaminopyridine and related compounds, which are used industrially as compounds and as components in the synthesis of a variety of useful materials. The synthesis proceeds by means of a chlorine-ammonia displacement in the presence of a copper source.

专利号:US-11325888-B2
优先权日:2017-08-11
标 题:Method for the synthesis of monoprotected bifunctional prodrugs and antibody drug conjugates based thereon as well as a method for preparing antibody drug conjugates
发明人：TIETZE LUTZ F
权利人:GEORG AUGUST UNIV GOETTINGEN STIFTUNG OEFFENTLICHEN RECHTS
摘要:The present invention relates to a method for the synthesis of compounds useful in the preparation of antibody drug conjugates (ADC), namely, monoprotected dimeric bifunctional prodrugs based on duocarmycin analogs. In a further aspect, compounds obtained by the method according to the present invention are provided. The monoprotected bifunctional prodrug is used for preparing antibody drug conjugates composed of an antibody moiety and the monoprotected bifunctional prodrug. The antibody compound conjugates thus obtained are provided. Further, a method of preparing an antibody drug conjugate composed of two identical or two different antibody moieties is provided as well as the antibody compound conjugate containing two different antibody moieties accordingly. These conjugates can be used in pharmaceutical compositions, in particular, for use in treatment of tumors, e.g. for use in ADC therapy.

专利号:US-10633398-B2
优先权日:2014-06-18
标 题 :Synthesis of zinc-lysine complex from zinc chloride
发明人：NAWROCKI SHIRI; SUBRAMANYAM RAVI; PAN LONG
权利人:COLGATE PALMOLIVE CO
摘要:The disclosure provides an improved synthesis for a zinc-lysine complex having the formula [Zn(C 6 H 14 N 2 O 2 ) 2 Cl] + Cl − , in which zinc chloride is reacted with lysine, in aqueous solution. The disclosure also provides oral care and personal care compositions comprising the complex prepared by the synthesis, and methods of using these complexes and compositions.

专利号:US-7335717-B2
优先权日:1998-12-18
标 题 :Methods, compositions, and biomimetic catalysts for the synthesis of silica, polysilsequioxanes, polysiloxanes, non-silicon metalloid-oxygen networks, polymetallo-oxanes, and their organic or hydrido conjugates and derivatives
发明人：MORSE DANIEL E; KISAILUS DAVID; ROTH KRISTIAN M
权利人:UNIV CALIFORNIA
摘要:The in vitro polymerization of silica, silicone, non-silicon metalloid-oxane and metallo-oxane polymer networks, by combining a catalyst and a substrate to polymerize the substrate to form silica, polysiloxanes, polymetalloid-oxanes polymetallo-oxanes (metal oxides), polyorganometalloid oxanes, polyorganometallo oxanes, and the polyhydrido derivatives thereof, at about neutral pH. The nanostructure-directing catalysts have a nucleophilic functionality and a hydrogen-bonding acceptor group, and include: silicateins, enzymes that work by a mechanism functionally related to that of the silicateins; self-assembling peptides related to those synthesized and demonstrated capable of acting as biomimetic substitutes for the silicateins; non-peptide-based synthetic polymers containing a nucleophilic group and a hydrogen bonding amine such that the polymer functions by a mechanism of action related to that of the silicateins; materials having such chemical functionality as a nucleophilic group and or a hydrogen bonding amine which, acting in concert with nanoconfinement and or chemical functionality of the surface or matrix to which the functionality is attached, acts catalytically by a mechanism related to that of the silicateins; and small-molecule non-polymeric biomimetic catalysts that operate by the same mechanism as silicateins.

专利号:US-8722384-B2
优先权日:1997-04-11
标 题:Methods and compositions for synthesis of long chain polyunsaturated fatty acids
发明人：KNUTZON DEBORAH; MUKERJI PRADIP; HUANG YUNG-SHENG; THURMOND JENNIFER; CHAUDHARY SUNITA; LEONARD AMANDA EUN-YEONG
权利人:KNUTZON DEBORAH; MUKERJI PRADIP; HUANG YUNG-SHENG; THURMOND JENNIFER; CHAUDHARY SUNITA; LEONARD AMANDA EUN-YEONG; CALGENE LLC; ABBOTT LAB
摘要:The present invention relates to fatty acid desaturases able to catalyze the conversion of oleic acid to linoleic acid, linoleic acid to γ-linolenic acid, or of alpha-linolenic acid to stearidonic acid. Nucleic acid sequences encoding desaturases, nucleic acid sequences which hybridize thereto, DNA constructs comprising a desaturase gene, and recombinant host microorganism or animal expressing increased levels of a desaturase are described. Methods for desaturating a fatty acid and for producing a desaturated fatty acid by expressing increased levels of a desaturase are disclosed. Fatty acids, and oils containing them, which have been desaturated by a desaturase produced by recombinant host microorganisms or animals are provided. Pharmaceutical compositions, infant formulas or dietary supplements containing fatty acids which have been desaturated by a desaturase produced by a recombinant host microorganism or animal also are described.

专利号:US-7745694-B1
优先权日:1997-04-11
标 题:Methods and compositions for synthesis of long chain polyunsaturated fatty acids in plants
发明人：KNUTZON DEBORAH; MUKERJI PRADIP; HUANG YUNG-SHENG; THURMOND JENNIFER; CHAUDHARY SUNITA; LEONARD AMANDA EUN-YEONG
权利人:MONSANTO TECHNOLOGY LLC
摘要:The present invention relates to compositions and methods for preparing polyunsaturated long chain fatty acids in plants, plant parts and plant cells, such as leaves, roots, fruits and seeds. Nucleic acid sequences and constructs encoding fatty acid desaturases, including Δ5-desaturases, Δ6-desaturases and Δ12-desaturases, are used to generate transgenic plants, plant parts and cells which contain and express one or more transgenes encoding one or more desaturases. Expression of the desaturases with different substrate specificities in the plant system permit the large scale production of polyunsaturated long chain fatty acids such as docosahexaenoic acid, eicosapentaenoic acid, α-linolenic acid, gamma-linolenic acid, arachidonic acid and the like for modification of the fatty acid profile of plants, plant parts and tissues. Manipulation of the fatty acid profiles allows for the production of commercial quantities of novel plant oils and products.