专利号:US-2003083352-A1 优先权日:2000-07-31 标 题 :Synthesis of imidazole intermediates 发明人:HELAL CHRISTOPHER J 权利人:PFIZER 摘要:The invention provides a method for synthesis of compounds of formula n n n wherein R 1 and R 19 are as defined. Compounds of formula 12 are useful as intermediates for synthesizing compounds having pharmacological activity inhibiting cdk5, cdk2, and GSK-3.
专利号:US-2023174490-A1 优先权日:2020-03-18 标 题 :Improved synthesis of 6-aryl-4-aminopicolinates 发明人:ZHANG CHUNMING; TU SIYU; LENG RONALD B; IRVINE NICHOLAS; SCHUITMAN ABRAHAM; SHINKLE AARON; DEVARAJ JAYACHANDRAN; ZU CHENGLI 权利人:CORTEVA AGRISCIENCE LLC 摘要:The present disclosure relates to improved methods of synthesizing 6-aryl-4-aminopicolinates, such as arylalkyl and alkyl 4-amino-3-chloro-6-(4-chloro-2-fluoro-3-methoxyphenyl)pyridine-2-carboxylates.
专利号:US-9676783-B2 优先权日:2008-10-22 标 题:Method of treatment using substituted pyrazolo[1,5-A] pyrimidine compounds 发明人:HAAS JULIA; ANDREWS STEVEN W; JIANG YUTONG; ZHANG GAN 权利人:ARRAY BIOPHARMA INC 摘要:Compounds useful in the synthesis of compounds for treating pain, cancer, inflammation, neurodegenerative disease or Typanosoma cruzi infection in a mammal.
专利号:US-2023357155-A1 优先权日:2020-03-18 标 题:Improved synthesis of 4-amino-6-(heterocyclic)picolinates 发明人:CANTURK BELGIN; DEVARAJ JAYACHANDRAN; HAZARI AMARUKA; KASSL CHRISTOPHER; LEE MELISSA; LI FANGZHENG; LOWE CHRISTIAN T; SIDDALL THOMAS L; WHITEKER GREGORY T; ZHANG CHUNMING 权利人:CORTEVA AGRISCIENCE LLC 摘要:The present disclosure relates to improved processes for preparing 4-amino-6-(heterocyclic)picolinates.
专利号:EP-0747486-B1 优先权日:1995-06-07 标题:Microbiological method for the synthesis of heteroaromatic caboxylic acids using microorganisms of the genus Alcaligenes
专利号:CN-115298167-A 优先权日:2020-03-18 标 题 :Improved Synthesis of 6-Aryl-4-Aminopicolinate