CAS: 4089-07-0; H-Tyr-Oet.Hcl

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L-酪氨酸置于氯化亚砜体系中,化学反应生成 L-酪氨酸乙酯盐酸盐
参考文献:Tricyclic Compound And Pharmaceutical Use Thereof
标题:Tricyclic Compound And Pharmaceutical Use Thereof
摘要:本发明的化合物是一种三环衍生物,化学式为1或其药学上可接受的盐,具有优异的抑制血清素活性的效果.因此,含有该化合物的制药组合物可用于预防或治疗与血清素活化有关的代谢性疾病等.

专利信息

专利号:US-10442757-B2
优先权日:2017-06-07
标 题 :Synthesis of tyrosine derived diphenol monomers
发明人：PULAPURA SATISH; BUEVICH FATIMA; CHEN XIANGJI; LYU SUPING
权利人:TYRX INC; MEDTRONIC INC
摘要:A method for preparing diphenol compounds includes adding a hydroxyphenyl carboxylic acid, a tyrosine ethyl ester, hydroxybenzotriazole hydrate and a solvent and stirring to produce a first solution. EDCI HCl is added to the first solution to produce a first mixture. Ethyl acetate is added to the first mixture to produce a second mixture. The second mixture is added to sodium chloride to produce a third mixture having layer separation. An aqueous layer is removed from the third mixture. The third mixture is extracted with reagents after the aqueous layer has been removed from the third mixture to produce a fourth mixture. Magnesium sulfate is added to the fourth mixture to produce a fifth mixture. The fifth mixture is filtered to produce filtrate. The filtrate is concentrated. Crystallization of the concentrated filtrate is induced. Methylene chloride is added to the crystallized filtrate to produce a solid product.

专利号:WO-2018226340-A1
优先权日:2017-06-07
标题:Synthesis of tyrosine derived diphenol monomers

专利号:US-2722526-A
优先权日:1952-09-24
标题:Trialkylphosphites as acid acceptors in the synthesis of amides
发明人：WASHINGTON ANDERSON GEORGE; WILLIAM YOUNG RICHARD
权利人:AMERICAN CYANAMID CO

专利号:US-2018354892-A1
优先权日:2017-06-07
标题:Synthesis of tyrosine derived diphenol monomers

专利号:EP-3634944-A1
优先权日:2017-06-07
标 题 :Synthesis of tyrosine derived diphenol monomers

专利号:CN-110637007-B
优先权日:2017-06-07
标 题:Synthesis of tyrosine-derived diphenolic monomers