CAS: 394-64-9; 1-Fluoro-2,3-Dimethoxybenzene

上下游产品

1,2-dimethoxybenzene 2-fluoro-6-methoxyphenol dimethyl sulfate 2-fluoro-6-hydroxyanisole 3-fluor°C atechol α-chloro-2-fluoro-3,4-dimethoxytoluene 2-fluoro-3,4-dimethoxybenzaldehyde 3-fluoro-4,5-dimethoxybenzaldehyde

📜间氟苯甲醚置于potassium Carbonate体系中,用 丙酮 用作溶剂,化学反应 12.0H,反应生成1-氟-2,3-二甲氧基苯
参考文献:Adejare,Adeboye; Miller,Duane D.,Journal Of Chemical Research,Miniprint,1986,# 1,P. 171-193
标题:Adejare,Adeboye; Miller,Duane D.,Journal Of Chemical Research,Miniprint,1986,# 1,P. 171-193

专利信息

专利号:WO-9429243-A1
优先权日:1993-06-11
标 题 :Synthesis of substituted triphenylenes, useful as discotic liquid crystals
发明人：BUSHBY RICHARD JAMES; CAMMINDGE ANDREW NEIL; HEADDOCK GARETH; BORNER RUTH CAROL; BODEN NEVILLE
权利人:BRITISH TECH GROUP; BUSHBY RICHARD JAMES; CAMMINDGE ANDREW NEIL; HEADDOCK GARETH; BORNER RUTH CAROL; BODEN NEVILLE
摘要:Unsymmetrically substituted triphenylenes required in the synthesis of polymeric discotic liquid crystals are made using iron (III) chloride in organic solvent at room temperature to effect the oxidative coupling of 1,2-dialkoxybenzenes to 3,3',4,4'-tetraalkoxybiphenyls. This is followed by a reductive workup. The same oxidation-reduction protocol also proves effective in the trimerisation of 1,2-dialkoxybenzenes.

专利号:US-7507851-B2
优先权日:2003-09-24
标 题 :Halocombstatins and methods of synthesis thereof
发明人：PETTIT GEORGE R; MINARDI MATHEW D; ROSENBERG HEIDI J
权利人:ARIZONA BOARD OF REGENTS A STA
摘要:The invention relates to novel compounds denominated halocombstatins. The halocombstatins are derivatives of combretastatin A-3, and include compounds that exhibit cancer growth cell inhibition against a panel of human cancer cell lines and the murine P388 leukemia, as well as activity as inhibitors of tubulin polymerization and inhibitors of the binding of colchicine to tubulin.

专利号:US-2011104055-A1
优先权日:2002-05-31
标题:Substituted n-aryl benzamides and related compounds for treatment of amyloid diseases and synucleinopathies
发明人：SNOW ALAN; WEIGELE MANFRED; LARSEN LESLEY; NGUYEN BETH; LAKE THOMAS; CASTILLO GERARDO; SANDERS VIRGINIA; WEAVERS REX T; LORIMER STEPHEN; LARSEN DAVID; COFFEN DAVID L; COFFEN CHARLOTTE
权利人:SNOW ALAN; WEIGELE MANFRED; LARSEN LESLEY; NGUYEN BETH; LAKE THOMAS; CASTILLO GERARDO; SANDERS VIRGINIA; WEAVERS REX T; LORIMER STEPHEN; LARSEN DAVID; COFFEN DAVID L; COFFEN CHARLOTTE
摘要:Compounds and their pharmaceutically acceptable salts, their synthesis and labeling, pharmaceutical compositions containing them, and their use in the treatment of amyloid diseases, including Aβ amyloidosis, such as observed in Alzheimer's disease, IAPP amyloidosis, such as observed in type 2 diabetes, and synucleinopathies, such as observed in Parkinson's disease, and the manufacture of medicaments for such treatment are provided. Also provided is the use of the disclosed compounds as imaging agents and methods for in vivo imaging and detection of amyloid and synuclein.

专利号:EP-0703885-A1
优先权日:1993-06-11
标 题:Synthesis of substituted triphenylenes, useful as discotic liquid crystals

专利号:GB-2279072-A
优先权日:1993-06-11
标题:Synthesis of substituted triphenylenes useful for discotic liquid crystals

专利号:US-7223747-B2
优先权日:2003-09-24
标题 :Halocombstatins and methods of synthesis thereof