专利号:US-9365494-B2 优先权日:2008-12-18 标 题 :Process for synthesis of amino-methyl tetralin derivatives 发明人:DURKIN KIERAN; FISHER LAWRENCE EMERSON; MEILI ARTHUR; SCALONE MICHAELANGELO; SHI XIANQING; VITALE JUSTIN 权利人:DURKIN KIERAN; FISHER LAWRENCE EMERSON; MEILI ARTHUR; SCALONE MICHAELANGELO; SHI XIANQING; VITALE JUSTIN; ROCHE PALO ALTO LLC 摘要:Methods for producing a compound of formula k1 or k2 n nby reducing a dihydronapthalene amide compound of formula in n nwith hydrogen gas in the presence of a ruthenium catalyst of formula j1 or j2n nRu(Z) 2 (L)  j1;n nRu(E)(E′)(L)(D)  j2;n nwherein m, n, Ar, Y, R 1 E, E′, D, Z and L are as defined herein.
专利号:WO-2025056767-A1 优先权日:2023-09-15 标题 :Process for the preparation of enantiomerically enriched aliphatic amines 发明人:BOU HAMDAN FARHAN; GODINEAU EDOUARD; SMEJKAL TOMAS; DUMEUNIER RAPHAEL; BOUSSEMGHOUNE MOHAMED ABDELOUAHAB; BLUM MATHIAS 权利人:SYNGENTA CROP PROTECTION AG 摘要:The present invention relates to a process for the preparation of enantiomerically enriched cyclobutylamines of formula (I) from α-tertiary cyclobutanones and reacting said enantiomerically enriched cyclobutylamines to enantiomerically enriched cyclobutylamides. Such compounds are useful intermediates in the synthesis of microbiocidal thiazole compounds.
专利号:US-5780692-A 优先权日:1995-12-28 标 题:Process for producing optically active benzhydrol compounds 发明人:SAKAGUCHI MINZO; IMAI TAKASHI; MIURA TAKASHI; YAMAZAKI TETSURO 权利人:TAKASAGO PERFUMERY CO LTD 摘要:A process for producing a benzhydrol compound (II) which comprises hydrogenating a benzophenone compound (I) in the presence of a hydrogenation catalyst consisting of a transition metal complex, a base and an optically active diamine compound: (I) (II) wherein R1 to R10 each represents H, OH, C1-4 alkyl, C1-4 alkoxy, C1-4 alkanoyl, etc., R2 and R3, and R8 and R9 may form -CH=CH-CH=CH-, or any two of R1 to R9 adjacent to each other may be bonded to thereby form -OCH2O- or -(CH2)3-. By using this process, optically active benzhydrol compounds which have a high purity and are useful as, for example, intermediates in the synthesis of drugs can be produced by simple procedures.
专利号:CA-2743978-A1 优先权日:2008-12-18 标 题:Process for synthesis of amino-methyl tetraline derivatives
专利号:RU-2127267-C1 优先权日:1993-09-13 标题 :Method of enantioselective synthesis of optically active substituted derivatives of 5,6-dihydro-2h-pyrane-2-one
专利号:US-8119842-B2 优先权日:2008-12-18 标题 :Process for synthesis of amino-methyl tetralin derivatives