CAS: 3063-71-6; (2R,4S,5R,6R)-5-Acetamido-2-(((((2R,3S,4R,5R)-5-(4-Amino-2-Oxopyrimidin-1(2H)-yl)-3,4-Dihydroxytetrahydrofuran-2-yl)Methoxy)(Hydroxy)Phosphoryl)Oxy)-4-Hydroxy-6-((1R,2R)-1,2,3-Trihydroxypropyl)Tetrahydro-2H-Pyran-2-Carboxylic Acid

上下游产品

CAS号72-87-7 N-acelyl-D-gluc... | CAS号113-24-6 丙酮酸钠 | CAS号65-47-4 5'-三磷酸胞苷 | CAS号7512-17-6 N-乙酰-D-氨基葡萄糖 | CAS号84380-10-9 4,7,8,9-四-O-乙酰基... | CAS号19342-33-7 (2S,4S,5S,6R)-5... | CAS号24967-27-9 N-乙酰-2,3-二脱氢-2-...

专利信息

专利号:US-5714587-A
优先权日:1993-03-31
标 题 :Synthesis of anti-inflammatory compounds, and novel trisaccharides useful in the synthesis of anti-inflammatory compounds
发明人：LAINE ROGER A
权利人:UNIV LOUISIANA STATE; AGRICULTURAL AND MECHANICAL CO
摘要:Anti-inflammatory compounds are useful, for example, in treating arthritis and heart attack patients. Novel oligosaccharides useful in the rapid synthesis of certain anti-inflammatory compounds are disclosed, as is a rapid method of synthesizing the oligosaccharides. Low pH can loosen the acceptor specificity of galactosyltransferase (lactose synthase: EC 2.4.1.22), allowing the rapid synthesis of novel oligosaccharides. The disaccharides cellobiose (β1→4), laminaribiose (β1→3), gentiobiose (β1→6) and maltose (α1→4) acted as acceptors for lactose synthase under low pH conditions. From these four acceptors, the following four novel trisaccharides were synthesized: Gal p (β1→4)Glc p (β1→3) -Glc, Gal p (β1→4)Glc p (β1→4)-Glc, Gal p (β1→4)Glc p (β1→6)-Glc and Gal p (β1→4)Glc p (α1→4)Glc. These trisaccharides, and other oligosaccharides, may be synthesized in a few days with the disclosed technique, as opposed to the several months which would likely have been required with more traditional organic synthetic methods. These trisaccharides may be used as intermediates in the rapid synthesis of anti-inflammatory compounds.

专利号:US-6440703-B1
优先权日:1997-12-01
标 题 :Enzymatic synthesis of gangliosides
发明人：DEFREES SHAWN
权利人:NEOSE TECHNOLOGIES INC
摘要:This invention provides methods for practical in vitro synthesis of gangliosides and other glycolipids. The synthetic methods typically involve enzymatic synthesis, or a combination of enzymatic and chemical synthesis. One or more of the enzymatic steps is preferably carried out in the presence of an organic solvent.

专利号:US-5374541-A
优先权日:1993-05-04
标 题 :Combined use of β-galactosidase and sialyltransferase coupled with in situ regeneration of CMP-sialic acid for one pot synthesis of oligosaccharides
发明人：WONG CHI-HUEY; GAETA FEDERICO C A
权利人:SCRIPPS RESEARCH INST; CYTEL CORP
摘要:A single reaction vessel process for the synthesis of a sialylated galactoside is disclosed. The synthesis utilizes a β-galactosidase to catalyze the reaction of a galactose-containing substrate and an acceptor to form a new galactosyl glycoside that is then sialylated using a cyclic multienzyme synthesis system to form CMP-sialic acid that sialylates the formed galactosyl glycoside in the presence of an α-sialyltransferase. The value of K m /V max for the formed galactosyl glycoside as a substrate for the α-sialyltransferase is less than one-third the K m /V max value for the galactose-containing substrate for that α-sialyltransferase.

专利号:US-6156547-A
优先权日:1990-04-16
标 题:Apparatus for the synthesis of saccharide compositions
发明人：ROTH STEPHEN
权利人:NEOSE PHARM INC
摘要:This invention relates to an apparatus containing specific binary combinations of glycosyltransferases, for the synthesis of specific saccharide compositions such as, for example, oligosaccharides, polysaccharides, glycolipids, and glycopeptides.

专利号:US-5654412-A
优先权日:1996-05-29
标 题:Processes for the synthesis of sialyl Lewisx compounds
发明人：SRIVASTAVA OM; GREGSON JONATHAN M
权利人:GLYCOMED INC
摘要:Disclosed are processes for the chemical synthesis of sialyl Lewisx-Y compounds where Y is -OH, -NHR, -SH, -SR or -OR, and R is an aglycon of at least one carbon atom.

专利号:WO-2024165611-A1
优先权日:2023-02-07
标题:Production of a disaccharide and/or milk oligosaccharide by a cell with reduced synthesis of udp-glcnac
发明人：BEAUPREZ JOERI; DECOENE THOMAS; VERCAUTEREN ANNELIES
权利人:INBIOSE NV
摘要:The present invention is in the technical field of synthetic biology, metabolic engineering and cell cultivation. The invention provides a cell for production of a disaccharide and/or an oligosaccharide like a milk oligosaccharide wherein synthesis of UDP-N-acetylglucosamine in said cell is rendered less functional. The invention further provides use of said cell in a cultivation or incubation. The invention also describes methods for the production of a disaccharide and/or an oligosaccharide like a milk oligosaccharide using said cell as well as the purification of said disaccharide and/or oligosaccharide like a milk oligosaccharide.