CAS: 19891-85-1; 1-((1R,3Ar,5Ar,5Br,7Ar,9S,11Ar,11Br,13Ar,13Bs)-9-Hydroxy-3A,5A,5B,8,8,11A-Hexamethylicosahydro-1H-Cyclopenta[a]Chrysen-1-yl)Ethan-1-One

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上下游产品

(20RS)-lupane-3β,20,29-triol 3β-acetoxy-30-nor-lupan-20-one lupenol

合成工艺路线路线简述

    📜羽扇豆醇置于臭氧,二甲基硫体系中,用 二氯甲烷 用作溶剂,化学反应 1.42H,以240 Mg的收率获得3Beta-羟基-30-去甲羽扇烷-20-酮
    参考文献:Mishra,Namita; Kumar,Satish; Khare,Pritibha,Indian Journal Of Heterocyclic Chemistry,2014,Vol. 24,# 1,P. 97-110
    标题:Mishra,Namita; Kumar,Satish; Khare,Pritibha,Indian Journal Of Heterocyclic Chemistry,2014,Vol. 24,# 1,P. 97-110

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    ✅ COA系统入驻 | 共享模式

    主要参考文献

    参考标题:Design And Synthesis Of New Lupeol Derivatives And Their α-Glucosidase Inhibitory And Cytotoxic Activities
    作者:Hoang-Vinh-Truong Phan,Thuc-Huy Duong,Duc-Dung Pham,Hoang-Anh Pham,Van-Kieu Nguyen,Thi-Phuong Nguyen,Huu-Hung Nguyen,Ngoc-Hong Nguyen,Pornpat Sam-Ang,Kiettipum Phontree,Jirapast Sichaem |发布日期:2022.1.2
    摘要:Were Designed, Synthesised And Evaluated For Their α-Glucosidase Inhibitory And Cytotoxic Activities. Among Synthetic Derivatives, Lupeol Analogues 2B And 2E Containing A Benzylidene Chain Exhibited The Best Activity Against α-Glucosidase And Superior To The Positive Agent With The Ic50 Values Of 29.4 +/- 1.33 And 20.1 +/- 0.91 μm, Respectively. Lupeol Analogues 2D And 3A Showed Weak Cytotoxicity Against
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