CAS: 16909-09-4; (E)-3-(2,4-Dimethoxyphenyl)Acrylic Acid

该化合物是一种有机化合物,其特点是其丙基酸结构,具有替代芳香环,其特征为一种丙基酸结构,在苯环上存在两个甲氧基组,这增加了其亲脂性,并可能影响其生物活动.这种化合物通常具有以下特性:在室温下是固体,在药物和有机合成中具有潜在应用作用;其结构允许与生物目标发生潜在互动,从而引起对药用化学的兴趣.该化合物还可能表现出抗氧化性特性,在类似的芳香化合物中很常见.此外,其反应力可归因于丙基酸混合物的共生双结合,允许各种化学变异.与许多有机化合物一样,应注意安全和处理预防措施,因为如果浸泡或处理不当,可能会造成风险.

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相似化合物

6972-61-8 1363130-07-7 24393-63-3

上下游产品

(E)-2,4-dimethoxycinnamic acid ethyl ester (E)-3-(2,4-dimethoxy-phenyl)-acrylic acid methyl ester acetic anhydride 2,4-Dimethoxybenzaldehyde (E)-3-(2,4-dimethoxy-phenyl)-acrylic acid methyl ester 3-(2,4-Dimethoxy-phenyl)-3-(3,4-dimethoxy-phenyl)-propionsaeure (E)-2,4-dimethoxycinnamic acid ethyl ester 3-(2,4-dimethoxyphenyl)propyl alcohol

合成工艺路线路线简述

    📜7-甲氧基香豆素置于sodium Hydroxide,Potassium Carbonate体系中,化学反应生成反-2,4-二甲氧基肉桂酸
    参考文献:Tiemann; Will,Chemische Berichte,1882,Vol. 15,P. 2079,2080
    标题:Tiemann; Will,Chemische Berichte,1882,Vol. 15,P. 2079,2080

    海关参考信息

    专利信息


    专利号:US-5124478-A
    优先权日:1987-12-22
    标 题:Acid-labile anchor groups for the synthesis of peptide amides by a solid-phase method
    发明人:BREIPOHL GERHARD; KNOLLE JOCHEN; STUEBER WERNER
    权利人:HOECHST AG
    摘要:The invention relates to new compounds of the formula ##STR1## in which R 1 denotes (C 1 -C 8 )-alkyl, R 2 denotes an amino acid residue which is protected with a urethane protective group which can be eliminated with weak acid or base, or denotes an amino protective group which can be eliminated with weak acid or base, R 3 denotes hydrogen or (C 1 -C 4 )-alkyl, and Y 1 -Y 9 denote identical or different radicals hydrogen, (C 1 -C 4 )-alkyl, (C 1 -C 4 )-alkoxy or --O--(CH 2 ) n --COOH (with n=1 to 6), with one of these radicals being --O--(CH 2 ) n --COOH, or Y 1 , Y 2 and Y 5 -Y 9 denote identical or different radicals hydrogen, (C 1 -C 4 )-alkyl or (C 1 -C 4 )-alkoxy, Y 3 denotes hydrogen or (C 1 -C 8 )-alkoxy and Y 4 denotes --(CH 2 ) n --COOH or --NH--CO--(CH 2 ) n --COOH (with n=1 to 6). n Processes for the preparation thereof and the synthesis of peptide amides by a solid-phase method using these new compounds (spacers) are described.

    专利号:US-11746364-B2
    优先权日:2018-01-17
    标题 :Enzymatic synthesis of kavalactones and flavokavains
    发明人:PLUSKAL TOMÃ?S; Weng jing-ke
    权利人:WHITEHEAD INST BIOMEDICAL RES
    摘要:Disclosed are methods, compositions, proteins, nucleic acids, cells, vectors, compounds, reagents, and systems for the preparation of kavalactones, flavokavains, and kavalactone and flavokavain biosynthetic intermediates using enzymes expressed in heterologous host cells, such as microorganisms or plants, or using in vitro enzymatic reactions. This invention also provides for the expression of the enzymes by recombinant cell lines and vectors. Furthermore, the enzymes can be components of constructs such as fusion proteins. The kavalactones produced can be utilized to treat anxiety disorder, insomnia, and other psychological and neurological disorders. The flavokavains produced can be utilized to treat various cancers including colon, bladder, and breast cancers.

    专利号:PT-89297-B
    优先权日:1987-12-22
    标题 :METHOD FOR PREPARING NEW INTERMEDIATE COMPOUNDS FOR PEPTIDE SYNTHESIS AND PROCESS FOR SYNTHESIS OF PEPTIDE-AMIDES BY THE SOLID PHASE METHOD USING THE REFERRED COMPOUNDS

    专利号:US-2019271015-A1
    优先权日:2018-01-17
    标题 :Enzymatic synthesis of kavalactones and flavokavains

    专利号:US-10941429-B2
    优先权日:2018-01-17
    标 题:Enzymatic synthesis of kavalactones and flavokavains

    专利号:IL-88741-A
    优先权日:1987-12-22
    标 题:Aromatic compounds used for the synthesis of peptides and the process of producing peptides using such compounds

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    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献

    参考标题:Copper Catalyzed Cross-Coupling Reactions Of Carboxylic Acids: An Expedient Route To Amides, 5-Substituted γ-Lactams And α-Acyloxy Esters
    作者:S. Priyadarshini,P. J. Amal Joseph,M. Lakshmi Kantam
    摘要:A Convenient And Recyclable Catalytic Protocol For The Synthesis Of N,N-Dimethyl Substituted Amides, 5-Substituted γ-Lactams And α-Acyloxy Ethers From Carboxylic Acids Using Cuo Nanoparticles And Tbhp Is Described.

    合成参考文献


    摘要:I. Hsu and L. F. Koons, J. Indian Chem. Soc. 44, 540 (1967).
    参考文献:10.1186/s12934-015-0353-y
    摘要:Sim GY, Yang S, Kim BG, Ahn J. Bacterial synthesis of N-hydroxycinnamoyl phenethylamines and tyramines. Microbial Cell Factories. 2015 Oct 13;14(1):162. doi: 10.1186/s12934-015-0353-y.
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