3003-84-7 = 821-09-0 反应条件:1.1 Reagents: Sodium Solvents: Diethyl Ether 标题:Olefinic Acids. Xvi. Synthesis Of δ10-Undecenoic Acid 作者:Gaubert,Peter; Et Al 参考文献:Journal Of The Chemical Society 日期:1937 卷标:1971 页码:1971-4]
71-50-1 = 821-09-0 [标题:Reaction Conditions 标题:Study Of Interactions Between Alcohol And Amine Functions. Thermolysis Of Hydroxides And Salts Of ω-(Trialkylammonio)-1-Alkanols 作者:Barbry,Didier; Et Al 参考文献:Collection Of Czechoslovak Chemical Communications 日期:1983 卷标:48(6) 页码:1734-44]
1192-30-9 = 821-09-0 反应条件:1.1 Reagents: Lithium Solvents: Tetrahydrofuran; 0 °C; 2 H,Rt1.2 Reagents: Ammonium Chloride Solvents: Water; Rt 标题:Practical Synthesis Of Pent-4-Yn-1-Ol And Pent-4-En-1-Ol From Tetrahydrofurfuryl Halides 作者:Saito,Katsuya; Et Al 参考文献:Synthesis 日期:2023 卷标:55(17) 页码:2670-2673]
1192-30-9 = 821-09-0 反应条件:1.1 Reagents: Sodium Solvents: Diethyl Ether 标题:Stability Of The Hydrofuran Ring. Iii. The Mechanism Of The Rearrangements Accompanying The Rupture Of The Ring In Tetrahydrofuran Derivatives. The Preparation Of 2-Penten-1-Ol 作者:Paul,R. 参考文献:Bulletin De La Societe Chimique De France 日期:1935 卷标:2 页码:745-54]
2622-05-1 = 821-09-0 反应条件:1.1 Reagents: Copper Bromide (Cubr) 标题:Condensation Of Grignard Reagents With Rchbrch2Oh Type Bromohydrins. Effect Of Copper(I) Salts 作者:Bourgain-Commercon,Monique; Et Al 参考文献:Bulletin De La Societe Chimique De France 日期:1980 卷标:289 页码:289-94]
2100-17-6 = 821-09-0 反应条件:1.1 Reagents: Formic Acid Catalysts: Molybdenum,(Acetonitrile)Tricarbonyl[(2,3,4,5-η)-2,3,4,5-Tetraphenyl-2,4-Cyclop... Solvents: Benzene; Rt -> 65 °C; 12 H,65 °C 标题:Transfer Hydrogenation Of Aldehydes,Allylic Alcohols,Ketones,And Imines Using Molybdenum Cyclopentadienone Complexes 作者:Wu,Weiwei; Et Al 参考文献:Organometallics 日期:2018 卷标:37(9) 页码:1428-1431]
2100-17-6 = 821-09-0 [标题:Reaction Conditions 标题:Photo-Induced Copper-Catalyzed Alkynylation And Amination Of Remote Unactivated C(Sp3)-H Bonds 作者:Cao,Zhusong; Et Al 参考文献:Chemical Science 日期:2021 卷标:12(13) 页码:4836-4840]
5390-04-5 = 821-09-0 反应条件:1.1 Reagents: Hydrogen Catalysts: Palladium,Silver Solvents: Ethanol; 1 H,Rt 标题:Design Of Core-Pd/shell-Ag Nanocomposite Catalyst For Selective Semihydrogenation Of Alkynes 作者:Mitsudome,Takato; Et Al 参考文献:Acs Catalysis 日期:2016 卷标:6(2) 页码:666-670]
5390-04-5 = 821-09-0 反应条件:1.1 Reagents: Potassium Hydroxide,Water Catalysts: Copper; 15 Min,25 °C 标题:Highly Selective Electrocatalytic Alkynol Semi-Hydrogenation For Continuous Production Of Alkenols 作者:Bu,Jun; Et Al 参考文献:Nature Communications 日期:2023 卷标:14(1)]
108420-46-8 = 821-09-0 反应条件:1.1 Catalysts: Quinaldic Acid,Ruthenium(1+),Tris(Acetonitrile)(η5-2,4-Cyclopentadien-1-Yl)-,Hexafluorophosph... Solvents: Methanol; 3 H,30 °C 标题:Cpruiipf6/quinaldic Acid-Catalyzed Chemoselective Allyl Ether Cleavage. A Simple And Practical Method For Hydroxyl Deprotection 作者:Tanaka,Shinji; Et Al 参考文献:Organic Letters 日期:2004 卷标:6(11) 页码:1873-1875]
108420-46-8 = 821-09-0 反应条件:1.1 Reagents: Aniline,Biphenyl Catalysts: Palladium(1+),[[3,4-Bis(4-Methoxyphenyl)-3-Cyclobutene-1,2-Diylidene]Bis[[2,4,6...; 3 H,50 °C 标题:Facile And Selective Deallylation Of Allyl Ethers Using Diphosphinidenecyclobutene-Coordinated Palladium Catalysts 作者:Murakami,Hiromi; Et Al 参考文献:Journal Of Organic Chemistry 日期:2004 卷标:69(13) 页码:4482-4486]
1730-25-2 + 75-21-8 = 821-09-0 [标题:Reaction Conditions 标题:ω-Aminoalkyl-Substituted Silanes. I. Synthesis And Reactivity Of Aminoalkylsilanes With Sior And Sih Functional Groups 作者:Saratov,I. E.; Et Al 参考文献:Zhurnal Obshchei Khimii 日期:1981 卷标:51(2) 页码:396-404]
1730-25-2 + 75-21-8 = 821-09-0 [标题:Reaction Conditions 标题:Homolytic Displacement At Saturated Carbon. Part 9. The Reactions Of Trichloromethanesulfonyl Chloride With Pent-4-Enylcobaloximes And With Olefins. A Novel Route To (Trichloroethyl)Sulfolanes Via An Shi Mechanism 作者:Ashcroft,Martyn R.; Et Al 参考文献:Journal Of Organic Chemistry 日期:1984 卷标:49(10) 页码:1751-61]
26842-48-8 = 821-09-0 反应条件:1.1 Reagents: Tert-Butyllithium Solvents: Diethyl Ether,Pentane1.2 Reagents: Water 标题:Preparation And Reactions Of 3-Oxa- And 4-Oxa-5-Hexenyllithiums 作者:Bailey,William F.; Et Al 参考文献:Heteroatom Chemistry 日期:1992 卷标:3(1) 页码:55-61]
26842-48-8 = 821-09-0 [标题:Reaction Conditions 标题:Product Subclass 23: γ-Lithio Ethers And Related Compounds 作者:Caine,Drury 参考文献:Science Of Synthesis 日期:2006 卷标:8 页码:775-794]
863306-26-7 = 821-09-0 反应条件:1.1 Reagents: Zinc Acetate Dihydrate Solvents: Methanol,Dichloromethane; 1.5 H,Rt 标题:Picolinyl Group As An Efficient Alcohol Protecting Group: Cleavage With Zn(Oac)2.2H2O Under A Neutral Condition 作者:Baek,Ju Yuel; Et Al 参考文献:Tetrahedron Letters 日期:2005 卷标:46(31) 页码:5143-5147]
= 821-09-0 反应条件:1.1 Catalysts: Methanesulfonic Acid,1,1,1-Trifluoro-,Erbium(3+) Salt (3:1) Solvents: Ethanol; 24 Min,80 °C 标题:An Eco-Sustainable Erbium(Iii)-Catalyzed Method For Formation/cleavage Of O-Tert-Butoxy Carbonates 作者:Procopio,Antonio; Et Al 参考文献:Green Chemistry 日期:2011 卷标:13(2) 页码:436-443]
14697-46-2 = 821-09-0 反应条件:1.1 Reagents: Triethyl Orthoformate 标题:Olefin Synthesis By Deoxygenation Of Vicinal Diols 作者:Block,Eric 参考文献:Organic Reactions (Hoboken 日期:1984 卷标:30]
3003-84-7 = 821-09-0 反应条件:1.1 Reagents: Sodium Solvents: Diethyl Ether 标题:γ-Ethylenic Alcohols. I. Preparation Of 4-Penten-1-Ol 作者:Paul,R.; Et Al 参考文献:Bulletin De La Societe Chimique De France 日期:1943 卷标:10 页码:484-5]
67288-03-3 = 821-09-0 反应条件:1.1 Catalysts: Methanesulfonic Acid,1,1,1-Trifluoro-,Erbium(3+) Salt (3:1) Solvents: Methanol; 100 °C 标题:An Eco-Sustainable Erbium(Iii) Triflate Catalyzed Formation And Cleavage Of Tert-Butyl Ethers 作者:Procopio,Antonio; Et Al 参考文献:Synthesis 日期:2011 卷标:(1) 页码:73-78]
2100-17-6 = 821-09-0 反应条件:1.1 Reagents: Ferrocene Catalysts: Manganese(2+),Dibromohexacarbonyl[μ-[4-(1,1-Dimethylethyl)-2,6-Bis[6-(1-Methyl-... Solvents: Thf-D8 标题:Chemoselective Electrochemical Hydrogenation Of Ketones And Aldehydes With A Well-Defined Base-Metal Catalyst 作者:Fokin,Igor; Et Al 参考文献:Chemistry - A European Journal 日期:2020 卷标:26(62) 页码:14137-14143]
180259-48-7 = 821-09-0 反应条件:1.1 Reagents: Trifluoroacetic Acid,Benzene,1-Methoxy-4-[(1-Phenylethoxy)Methyl]- Solvents: Dichloromethane; 10 Min,21 °C 标题:Mild,Selective Deprotection Of Pmb Ethers With Triflic Acid/1,3-Dimethoxybenzene 作者:Jung,Michael E.; Et Al 参考文献:Tetrahedron Letters 日期:2011 卷标:52(46) 页码:6051-6054]
26842-48-8 = 821-09-0 反应条件:1.1 Reagents: Tert-Butyllithium Solvents: Diethyl Ether,Pentane 标题:The Conversion Of 4-Oxa-5-Hexenyllithiums To 4-Alken-1-Ols: A Novel [1,4]-Wittig Rearrangement 作者:Bailey,William F.; Et Al 参考文献:Tetrahedron Letters 日期:1991 卷标:32(35) 页码:4425-6]
14697-46-2 = 821-09-0 反应条件:1.1 Reagents: Triphenylphosphine,Oxygen Catalysts: Rhenium Oxide (Re2O7); 1 H,Rt -> 165 °C 标题:Rhenium-Catalyzed Deoxydehydration Of Renewable Triols Derived From Sugars 作者:Wozniak,Bartosz; Et Al 参考文献:Green Chemistry 日期:2018 卷标:20(19) 页码:4433-4437]
3003-84-7 = 821-09-0 反应条件:1.1 Reagents: Lithium Solvents: Tetrahydrofuran; 0 °C; 4 H,Rt1.2 Reagents: Ammonium Chloride Solvents: Water; Rt 标题:Practical Synthesis Of Pent-4-Yn-1-Ol And Pent-4-En-1-Ol From Tetrahydrofurfuryl Halides 作者:Saito,Katsuya; Et Al 参考文献:Synthesis 日期:2023 卷标:55(17) 页码:2670-2673]
5831-70-9 = 821-09-0 反应条件:1.1 Reagents: Indium Solvents: Methanol; 4.5 H,Rt; Rt -> 65 °C; 3 - 5 H,60 - 65 °C 标题:Ultrasound-Accelerated Synthesis Of Chiral Allylic Alcohols Promoted By Indium Metal 作者:Yadav,J. S.; Et Al 参考文献:Tetrahedron 日期:2003 卷标:59(28) 页码:5333-5336]
6581-54-0 = 821-09-0 反应条件:1.1 Reagents: Water Solvents: Water 标题:β-Halo Ether Synthesis Of Olefinic Alcohols: Stereochemistry Of The Ring-Scission Of 2-Substituted-3-Halotetrahydropyrans And -Furans 作者:Crombie,Leslie; Et Al 参考文献:Journal Of The Chemical Society 日期:1985 卷标:(9) 页码:1983-95]
1576-85-8 = 821-09-0 反应条件:1.1 Reagents: Lithium Aluminum Hydride Solvents: Diethyl Ether,Tetrahydrofuran; 2 H,0 °C; 1 H,0 °C -> Rt1.2 Reagents: Water; 5 Min,Rt1.3 Reagents: Sodium Hydroxide Solvents: Water; 5 Min,Rt1.4 Reagents: Water; Rt 标题:The Facile Preparation Of Alkenyl Metathesis Synthons 作者:Baughman,Travis W.; Et Al 参考文献:Tetrahedron 日期:2004 卷标:60(48) 页码:10943-10948]
1576-85-8 = 821-09-0 反应条件:1.1 Reagents: Potassium Carbonate,Hydrogen Catalysts: Stereoisomer Of [p,P-Bis(1,1-Dimethylethyl)-N-[2-[[(2-Pyridinyl-κn)Methyl]Amino-... Solvents: Isopropanol; 2 H,50 Bar,100 °C 标题:Chemoselective Hydrogenation Of Carbonyl Compounds And Acceptorless Dehydrogenative Coupling Of Alcohols 作者:Spasyuk,Denis; Et Al 参考文献:Journal Of The American Chemical Society 日期:2015 卷标:137(11) 页码:3743-3746]
64841-44-7 = 821-09-0 反应条件:1.1 Reagents: Lithium Chloride Solvents: Dimethyl Sulfoxide,Water 标题:A Mild And Efficient Method For Selective Deprotection Of Tetrahydropyranyl Ethers To Alcohols 作者:Maiti,Gourhari; Et Al 参考文献:Journal Of Organic Chemistry 日期:1996 卷标:61(17) 页码:6038-6039]
95650-55-8 = 821-09-0 [标题:Reaction Conditions 标题:Study Of Interactions Between Alcohol And Amine Functions. Ii. Thermolysis Of N-Oxides Of ω-(Dialkylamino)-1-Alkanols 作者:Barbry,Didier; Et Al 参考文献:Collection Of Czechoslovak Chemical Communications 日期:1984 卷标:49(10) 页码:2410-14
专利号:US-8569560-B2 优先权日:2006-10-13 标题 :Synthesis of terminal alkenes from internal alkenes via olefin metathesis 发明人:SCHRODI YANN; PEDERSON RICHARD L; KAIDO HIROKI; TUPY MICHAEL J 权利人:ELEVANCE RENEWABLE SCIENCES 摘要:This disclosure relates generally to olefin metathesis, and more particularly relates to the synthesis of terminal alkenes from internal alkenes using a cross-metathesis reaction catalyzed by an olefin metathesis catalyst. According to one aspect, for example, a method is provided for synthesizing a terminal olefin, the method comprising contacting, in the presence of a ruthenium alkylidene metathesis catalyst, an olefinic substrate comprised of at least one internal olefin with a cross metathesis partner comprised of an alpha olefinic reactant, under reaction conditions effective to allow cross-metathesis to occur, wherein the reaction conditions include a reaction temperature of at least 35° C. The methods, compositions, reactions and reaction systems herein disclosed have utility in the fields of catalysis, organic synthesis, and industrial chemistry.
专利号:US-10000432-B2 优先权日:2014-01-13 标 题 :Processes for the synthesis of chiral 1-alkanols 发明人:NEGISHI EI-ICHI 权利人:PURDUE RESEARCH FOUNDATION 摘要:The invention relates to highly enantioselective processes for the synthesis of chiral 1-alkanols via Zr-catalyzed asymmetric carboalumination of alkenes.
专利号:US-6846917-B2 优先权日:2001-01-23 标题:Solid- and solution-phase synthesis of heparin and other glycosaminoglycans 发明人:SEEBERGER PETER H; ORGUEIRA HERNAN; SCHELL PETER 权利人:MASSACHUSETTS INST TECHNOLOGY 摘要:Described is a modular, general synthetic strategy for the preparation in solution and on a solid support of heparin, heparin-like glycosaminoglycans, glycosaminoglycans and non-natural analogs of each of them. Additionally, the modular strategy provides the basis for the preparation of combinatorial libraries and parallel libraries of defined glycosaminoglycan oligosaccharides. The defined glycosaminoglycan structures may be used in high-throughput screening experiments to identify carbohydrate sequences that regulate a host of recognition and signal-transduction processes. The determination of specific sequences involved in receptor binding holds great promise for the development of molecular tools which will allow modulation of processes underlying viral entry, angiogenesis, kidney diseases and diseases of the central nervous system. Notably, the present invention enables the automated synthesis of glycosaminoglycans in much the same fashion that peptides and oligonucleotides are currently assembled.
专利号:US-8604141-B2 优先权日:1995-08-03 标 题 :High metathesis activity ruthenium and osmium metal carbene complexes 发明人:GRUBBS ROBERT H; SCHWAB PETER; NGUYEN SONBINH T 权利人:GRUBBS ROBERT H; SCHWAB PETER; NGUYEN SONBINH T; CALIFORNIA INST OF TECHN 摘要:Ruthenium and osmium carbene compounds that are stable in the presence of a variety of functional groups and can be used to catalyze olefin metathesis reactions on unstrained cyclic and acyclic olefins are disclosed. Also disclosed are methods of making the carbene compounds. The carbene compounds are of the formula n nwhere M is Os or Ru; R 1 is hydrogen; R is selected from the group consisting of hydrogen, substituted or unsubstituted alkyl, and substituted or unsubstituted aryl; X and X 1 are independently selected from any anionic ligand; and L and L 1 are independently selected from any neutral electron donor. The ruthenium and osmium carbene compounds of the present invention may be synthesized using diazo compounds, by neutral electron donor ligand exchange, by cross metathesis, using acetylene, using cumulated olefins, and in a one-pot method using diazo compounds and neutral electron donors. The ruthenium and osmium carbene compounds of the present invention may be used to catalyze olefin metathesis reactions including, but not limited to, ROMP, RCM, depolymerization of unsaturated polymers, synthesis of telechelic polymers, and olefin synthesis.
专利号:US-4288613-A 优先权日:1979-12-03 标 题:Cyclopentanone synthesis 发明人:LAROCK RICHARD C 权利人:UNIV IOWA STATE RES FOUND INC 摘要:A method of synthesis of cyclopentanones comprising cyclizing a 4-pentenal, preferably under an ethylene atmosphere, in the presence of a catalytically effective amount of a cyclizing, rhodium(I) para-substituted triarylphosphine catalyst.
专利号:US-3676505-A 优先权日:1969-12-29 标 题:4-(4-methylcyclohex-3-en-1-yl)pent-4-en-1-ol and a process for its synthesis 发明人:CRAWFORD ROBERT J 权利人:PROCTER & GAMBLE 摘要:Disclosed herein is the synthesis of 4-(4-methylcyclohex-3-en-1yl)pent-4-en-1-ol, a novel compound useful as a starting reagent for the production of lanceol and lanceal, known perfume materials. Limonene is first metalated and then reacted with ethylene oxide to give the novel compound. This compound can then be converted to a known aldehyde which can be used to produce lanceol and lanceal by known processes.
[参考文献]: Marina D Rvovic, Et Al. Mechanistic Investigation Of The Base-Promoted Cycloselenoetherification Of Pent-4-En-1-Ol. J Mol Model. 2011 Jun;17(6):1251-7.
合成参考文献
摘要:Diver, S. T., Science of Synthesis, (2009) 46, 125. 摘要:Michalak, M.; Gulajski, L.; Grela, K., Science of Synthesis, (2010) 47, 354. 摘要:Hopkinson, M. N.; Gouverneur, V., Science of Synthesis Knowledge Updates, (2011) 2, 130. 摘要:Durand, A.; Hemeon, I.; Singer, R. D., Science of Synthesis Knowledge Updates, (2013) 2, 144. 摘要:Okamoto, K.; Ohe, K., Science of Synthesis Knowledge Updates, (2020) 1, 36.