CAS: 78285-90-2; (4Ar,5R,6As,6Br,10S,12Ar,12Br,14Br)-5-Hydroxy-2,2,6A,6B,9,9,12A-Heptamethyl-10-(((2R,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-2-yl)Oxy)-1,3,4,5,6,6A,6B,7,8,8A,9,10,11,12,12A,12B,13,14B-Octadecahydropicene-4A(2H)-Carboxylic Acid
该化合物是来自Eclipta Prestrata(一种传统用于草药的植物)的生物活性三叶素沙邦因,该植物具有显著的药理特性,包括肝脏保护,抗炎和抗氧化性活动,其行动机制包括调制细胞信号路径,如NF-B和Nrf2, 有助于其治疗潜力.Ecliptasaponin A的特点是高度纯度和稳定性,适合药物研制和植物化学研究,其结构特性允许对肝脏紊乱,氧化性压力相关条件和免疫调控进行有针对性的研究.该化合物在标准化配方中可以找到,以确保实验应用的再生性.
- 英文名称(4Ar,5R,6As,6Br,10S,12Ar,12Br,14Br)-5-Hydroxy-2,2,6A,6B,9,9,12A-Heptamethyl-10-(((2R,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-2-yl)Oxy)-1,3,4,5,6,6A,6B,7,8,8A,9,10,11,12,12A,12B,13,14B-Octadecahydropicene-4A(2H)-Carboxylic Acid
- 中文名称刺囊酸-3-O-葡糖苷
- IUPAC名称(4aR,5R,6aS,6bR,10S,12aR,12bR,14bR)-5-hydroxy-2,2,6a,6b,9,9,12a-heptamethyl-10-(((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-1,3,4,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-octadecahydropicene-4a(2H)-carboxylic acid
- 其它别名EclalbasaponinII; Ecliptasaponin A
- CAS编号78285-90-2
- MFCD编号:MFCD00017386
- EINECS号:278-887-0
- 分子式:C36H58O9分子量:634.85
- 产品CID: 1777976
- 产品分类生物化工 → 提取物
物理性质
上下游产品
Pitheduloside E 78285-88-8合成工艺路线路线简述
📜Eclalbasaponin V 以 1,4-二氧六环,吡啶 作为反应溶剂,化学反应 3.0H,反应生成 刺囊酸-3-O-葡糖苷
参考文献:Studies On The Constituents Of Compositae Plants. Part Ii. Oleanane Glycosides From Eclipta Alba.
标题:Studies On The Constituents Of Compositae Plants. Part Ii. Oleanane Glycosides From Eclipta Alba.
摘要:From The Whole Parts Of Eclipta Alba Hassk.,Six New Oleanane Triterpene Glycosides,Named Eclalbasaponins I-Vi (1-6),Were Isolated. The Structures Of 1-6 Were Characterized As Echinocystic Acid Glycosides,And Of Those,5 And 6 Were Revealed To Be Sulfated Saponins On The Basis Of Chemical And Spectral Data.
DOI:10.1248/cpb.42.1336
海关参考信息
- 2901210000-乙烯
2901220000-丙烯
2905122000-异丙醇
2905310000-1,2-乙二醇 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
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合成参考文献
参考文献:10.1248/cpb.42.1336
摘要:YAHARA S, DING N, NOHARA T. Studies on the Constituents of Compositae Plants. Part II. Oleanane Glycosides from Eclipta alba. Chem. Pharm. Bull. 1994;42(6):1336–8. doi: 10.1248/cpb.42.1336.
参考文献:10.3390/molecules23112807
摘要:Hong GU, Lee JY, Kang H, Kim TY, Park JY, Hong EY, Shin YH, Jung SH, Chang HB, Kim YH, Kwon YI, Ro JY. Inhibition of Osteoarthritis-Related Molecules by Isomucronulatol 7-O-β-d-glucoside and Ecliptasaponin A in IL-1β-Stimulated Chondrosarcoma Cell Model. Molecules. 2018 Oct 29;23(11).
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