CAS: 628-36-4; 1,2-Diformylhydrazine

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16466-61-8 5394-50-3 185456-26-2

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CAS号64-18-6 甲酸 | CAS号77287-34-4 甲亚胺酸 | CAS号141-53-7 甲酸钠 | CAS号109-94-4 甲酸乙酯 | CAS号624-84-0 甲酰肼 | CAS号209797-65-9 ethyl 2-(4-chlo... | CAS号27643-43-2 3-(1,2,4-triazo... | CAS号25700-19-0 2-(1,2,4-triazo... | CAS号288-99-3 1,3,4-噁二唑 | CAS号289-06-5 噻二唑 | CAS号98581-86-3 4-(4-羟基苯基)-1,2,4-三唑 | CAS号288-88-0 1,2,4-三氮唑 | CAS号584-13-4 4-氨基-1,2,4-三氮唑 | CAS号15857-20-2 N-[formyl(methy... | CAS号157069-48-2 4-(4H-1,2,4-三氮唑... | CAS号16114-05-9 N,N'-双(二甲基氨基亚甲基)肼

甲酸乙酯置于一水合肼体系中,化学反应 48.0H,以99%的收率获得产物二甲酰肼
参考文献:Synthesis And Molecular Properties Of Formic Hydrazides
标题:Synthesis And Molecular Properties Of Formic Hydrazides
摘要:The Existence Of 1,3-Silatropic Transformation In N',N'-Dimethyl-N-(Trimethylsilyl)Formic Hydrazide Was Discovered. In The Crystal,Its Molecules Form Chains Due To Bifurcated Hydrogen Bonds.
DOI:10.1016/j.Mencom.2015.09.029

专利信息

专利号:US-12240835-B2
优先权日:2018-09-18
标题:Substituted benzamides as intermediates in the synthesis of inhibitors of tyrosine kinase enzymatic activity
发明人：ROMERO F ANTHONY; KIRSCHBERG THORSTEN A; HALCOMB RANDALL; XU YINGZI
权利人:TERNS PHARMACEUTICALS INC
摘要:Provided herein are compounds, preferably compounds inhibiting tyrosine kinase enzymatic activity of a protein selected from Abelson protein (ABL1), Abelson-related protein (ABL2), or a chimeric protein BCR-ABL1, compositions thereof, and methods of their preparation, and methods of inhibiting tyrosine kinase enzymatic activity of a protein selected from Abelson protein (ABL1), Abelson-related protein (ABL2), or a chimeric protein BCR-ABL1, and methods for treating diseases wherein modulation of BCR-ABL1 activity prevents, inhibits, or ameliorates the pathology and/or symptomology of the disease. Intermediates such as compounds of Formula (S23), which are useful in the synthesis of compounds inhibiting tyrosine kinase enzymatic activity of a protein selected from Abelson protein (ABL1), Abelson-related protein (ABL2), or a chimeric protein BCR-ABL1, are also provided.

专利号:US-7855285-B2
优先权日:2005-06-14
标 题:Methods for selective N-9 glycosylation of purines
发明人：ROBINS MORRIS J; ZHONG MINGHONG
权利人:UNIV BRIGHAM YOUNG
摘要:A process for providing regiospecific and highly stereoselective synthesis of 9-β anomeric purine nucleoside analogs is described. The introduction of the sugar moiety on to 6-(azolyl)-substituted purine bases is performed so that highly stereoselective formation of the β anomers of only the 9 position regioisomers of the purine nucleoside analogs (either D or L enantiomers) is obtained. This regiospecific and stereoselective introduction of the sugar moiety allows the synthesis of nucleoside analogs, and in particular 2′-deoxy, 3′-deoxy, 2′-deoxy-2′-halo-arabino and 2′,3′-dideoxy-2′-halo-threo purine nucleoside analogs, in high yields without formation of the 7-positional regioisomers. Processes for providing novel 6-(azolyl)purines for the regiospecific and highly stereoselective synthesis of 9-β anomeric purine nucleoside analogs are described. The compounds are drugs or intermediates to drugs.

专利号:US-10226449-B2
优先权日:2013-12-20
标 题:Heterocyclic modulators of lipid synthesis and combinations thereof
发明人：HEUER TIMOTHY SEAN; OSLOB JOHAN D; MCDOWELL ROBERT S; JOHNSON RUSSELL; YANG HANBIAO; EVANCHIK MARC; ZAHARIA CRISTIANA A; CAI HAIYING; HU LILY W; DUKE GREGORY; OHOL-GUPTA YAMINI; O'FARRELL MARIE
权利人:3 V BIOSCIENCES INC
摘要:Heterocyclic modulators of lipid synthesis are provided as well as pharmaceutically acceptable salts thereof; pharmaceutical compositions comprising such compounds; and methods of treating conditions characterized by dysregulation of a fatty acid synthase pathway by the administration of such compounds and combinations of such compounds and other therapeutic agents.

专利号:US-9428502-B2
优先权日:2012-07-03
标题:Heterocyclic modulators of lipid synthesis
发明人：OSLOB JOHAN D; MCDOWELL ROBERT S; JOHNSON RUSSELL; YANG HANBIAO; EVANCHIK MARC; ZAHARIA CRISTIANA A; CAI HAIYING; HU LILY W; WAGMAN ALLAN S
权利人:3-V BIOSCIENCES INC
摘要:Heterocyclic modulators of lipid synthesis are provided as well as pharmaceutically acceptable salts thereof; pharmaceutical compositions comprising such compounds; and methods of treating conditions characterized by disregulation of a fatty acid synthase pathway by the administration of such compounds.

专利号:EP-2402011-A1
优先权日:2004-08-25
标题:Intermediates in the synthesis of S-triazolyl alpha-mercaptoacetanildes as inhibitors of HIV reverse transcriptase

专利号:US-9112225-B2
优先权日:2011-05-12
标题 :Precursor formulation for battery active materials synthesis
发明人：YANG LU; WANG MIAOJUN; ZENG DONGLI
权利人:YANG LU; WANG MIAOJUN; ZENG DONGLI; APPLIED MATERIALS INC
摘要:Compositions and methods of forming battery active materials are provided. A solution of battery active metal cations and reactive anions may be blended with a fuel to yield a precursor mixture usable for synthesizing a battery active material for deposition onto a substrate. The battery active metal cations include lithium, manganese, cobalt, nickel, iron, vanadium, and the like. Reactive anions include nitrate, acetate, citrate, tartrate, maleate, azide, amide, and other lower carboxylates. Suitable fuels, which may be water miscible, may include amino compounds. Alcohols and sugars may be added to adjust carbon content and fuel combustion characteristics. An exothermic reaction is performed to convert the metals into battery active oxides.