参考标题:Thermodynamic Epimeric Equilibration And Crystallisation-Induced Dynamic Resolution Of Lobelanine, Norlobelanine And Related Analogues 作者:Z. Amara,G. Bernadat,P.-E. Venot,P. Retailleau,C. Troufflard,E. Drège,F. Le Bideau,D. Joseph 摘要:β-Aminoketone Subunit, Lobelanine Is Prone To Self-Catalyze Mutarotation In Solution. Through The Synthesis Of Original Lobelanine Analogues, We Studied The Influence Of (I) The Size Of The Central Heterocycle, (II) The Bulkiness Of The Nitrogen Protecting Group, And (III) The Phenacyl Arm Substituent On The Thermodynamic Equilibrium And Its Displacement By Crystallisation-Induced Dynamic Resolution
合成参考文献
参考文献:10.1016/0031-9422(90)85468-u 摘要:Zhang M, Wang J, Zhou S. Alkaloids triterpenoids of Lobelia davidii. Phytochemistry. 1990 Jan;29(4):1353–4. doi: 10.1016/0031-9422(90)85468-u.