CAS: 174913-09-8; 1-Bromo-4-Chloro-2-Methoxybenzene

上下游产品

2-Bromo-5-chlorophenol methyl iodide dimethyl sulfate 2-methoxy-4-chlorobenzoic acid (5-bromo-2-chloro-6-methoxyphenyl)(4-ethoxyphenyl)methanone 2-Bromo-5-chlorophenol tert-butyl 4-(4-chloro-2-methoxyphenyl)-3,6-dihydropyridine-1(2H)-carboxylate (5-bromo-2-chloro-4-methoxyphenyl)(4-ethylphenyl)methanone

4-氯-2-甲氧基苯甲酸置于potassium Phosphate,Tetrabuthylammonium Tribromide体系中,用 乙腈 用作溶剂,化学反应 16.0H,以83%的收率获得2-溴-5-氯苯甲醚
参考文献:芳香族羧酸的无过渡金属脱羧溴化反应†
标题:芳香族羧酸的无过渡金属脱羧溴化反应†
摘要:在过去的一个世纪中,将脂肪酸转化为卤代烷的方法取得了显着进展,然而,芳香族酸的类似脱羧溴化仍然是一个长期的挑战.开发有效的芳基溴化物合成方法非常重要,因为它们是合成中的通用试剂,并且存在于许多功能分子中.在此,我们报告了芳香族酸的无过渡金属脱羧溴化反应.该反应适用于许多富含电子的芳族和杂芳族酸,这些酸先前已被证明是hunsdiecker型反应的不良底物.此外,我们的初步机理研究表明,自由基中间体不参与该反应,这与经典的hunsdiecker型反应性相反.全面的,
Doi:10.1039/c8Sc01016A

专利信息

专利号:US-7968752-B2
优先权日:2003-06-16
标 题:Hydrolytically-resistant boron-containing therapeutics and methods of use
发明人：LEE VING; PLATTNER JACOB J; BENKOVIC STEPHEN J; BAKER STEPHEN J; MAPLES KIRK R; BELLINGER-KAWAHARA CAROLYN; AKAMA TSUTOMU; ZHANG YONG-KANG; SINGH RAJESHWAR; SAURO VITTORIO A
权利人:ANACOR PHARMACEUTICALS INC
摘要:Compositions and methods of use of borole derivatives, including benzoxaboroles, benzazaboroles and benzthiaboroles, as therapeutic agents for treatment of diseases caused by bacteria or viruses are disclosed, as well as methods for synthesis of said agents and compositions thereof.

专利号:TW-202317512-A
优先权日:2021-06-29
标 题 :Synthesis of substituted indole derivatives

专利号:US-2013059996-A1
优先权日:2010-04-09
标 题 :Boron-Containing PI-Electron Materials Incorporating Formally Aromatic and Neutral Borepin Rings
发明人：TOVAR JOHN DAYTON; CARUSO JR ANTHONY
权利人:TOVAR JOHN DAYTON; CARUSO JR ANTHONY
摘要:The synthesis, functionalization and characterization of borepin-based extended pi-electron molecules is disclosed. Bulky substituents shielded the vacant boron p-orbitals thus allowing synthetic manipulation and purification under ambient lab conditions. The presently disclosed borepin-containing compounds displayed reversible cathodic electrochemistry and can be viewed as n-type analogues to bent acene hydrocarbons.