CAS: 16957-70-3; (E)-2-Methylpent-2-Enoic Acid

该化合物是一种不饱和的碳酸,配有分子式C6H10O2.它配有双联体的跨形配置(E),有助于其独特的化学反应性和稳定性.该化合物通常用作有机合成的中间体,特别是在生产香料,药品和农用化学物方面.它的α,β-不饱和结构使它成为Michael添加剂和其他聚合反应的宝贵前体.复合物表现出中等酸性,可以参与酯化或恐吓过程.其定义明确的立体化学和纯度使其适合需要精确分子控制的应用.建议进行适当处理是因为在某些条件下可能会产生刺激和再活动.

结构式图片

欧盟法规

REACH注册ECHA物质C&L通报REACH预注册

上下游产品

CAS号623-36-9 2-甲基-2-戊烯醛 | CAS号79140-68-4 (E)-2-methyl-1-... | CAS号159999-59-4 methyl 3-acetyl... | CAS号1617-40-9 ethyl (E)-2-met... | CAS号637337-87-2 (E)-N-(2-hydrox... | CAS号84307-86-8 1,1-Bis(methylt... | CAS号1567-14-2 反-2-甲基-2-戊烯酸甲酯 | CAS号28892-68-4 2-hydroxy-2-met... | CAS号4111-09-5 2-Hydroxy-2-met... | CAS号133181-02-9 3-hydroxy-2-met... | CAS号39255-32-8 母菊酯 | CAS号105-30-6 2-甲基-1-戊醇 | CAS号1567-14-2 反-2-甲基-2-戊烯酸甲酯 | CAS号1617-37-4 (Z)-2-methylpen... | CAS号1617-40-9 ethyl (E)-2-met... | CAS号89301-90-6 pentan-2-yl 2-m... | CAS号1187-82-2 (S)-2-Methylval... | CAS号54653-29-1 2-bromopent-2-ene

合成工艺路线路线简述

  • 合成目标产物 Trans-2-Methyl-2-Pentenoic Acid 主要起始原料 2-Methyl-2-Pentenal
  • (文献来源)合成步骤主要原料 2-Methyl-2-Pentenal
2-羟基-2-甲基戊腈置于盐酸体系中,化学反应生成草莓酸
参考文献:Lucas; Prater,Journal Of The American Chemical Society,1937,Vol. 59,P. 1684
标题:Lucas; Prater,Journal Of The American Chemical Society,1937,Vol. 59,P. 1684

海关参考信息

专利信息


专利号:WO-2024012791-A1
优先权日:2022-07-11
标题 :Electrochemical synthesis of pyrazolines and pyrazoles
发明人:BÄR ROBIN MAXIMILIAN; FORD MARK JAMES; KALDAS SHERIF JAMES; WALDVOGEL SIEGFRIED; HOFMANN SILJA; LINDEN MARTIN
权利人:BAYER AG
摘要:The present invention relates to an electrochemical process for the synthesis of pyrazolines and pyrazoles of formula (I). The process can be especially used for the synthesis of the herbicide safener mefenpyr-diethyl.

专利号:WO-2023102600-A1
优先权日:2021-12-06
标题:Synthesis of amphiphilic block copolymers and polymeric nanofibers produced therefrom
发明人:ZETTERLUND PER B; ISHIZUKA FUMI; KIM HYUN JIN; CHATANI SHUNSUKE; NIINO HIROSHI
权利人:NEWSOUTH INNOVATIONS PTY LTD
摘要:The present disclosure relates to the field of synthesis of block copolymers, and polymeric nanofibers having a core-shell morphology produced therefrom. The present disclosure relates to the field of synthesis of block copolymers where one block is more hydrophobic than the other block and is a different composition. The disclosure also relates to uses of these polymeric nanofibers in various applications, such as reinforcing a polymeric matrix and for coatings applications.

专利号:WO-2009135600-A1
优先权日:2008-05-07
标题:Catalysts for the synthesis of polyurethanes
发明人:LINDNER STEFAN; BAHNMUELLER STEFAN; SCHMIDT AXEL; WEIKARD JAN; BUCHMEISER MICHAEL; BANTU BHASKER; FRIEDERICHS WOLFGANG; KRAUSE JENS; REITER STEPHAN
权利人:BAYER MATERIALSCIENCE AG; LINDNER STEFAN; BAHNMUELLER STEFAN; SCHMIDT AXEL; WEIKARD JAN; BUCHMEISER MICHAEL; BANTU BHASKER; FRIEDERICHS WOLFGANG; KRAUSE JENS; REITER STEPHAN
摘要:The invention relates to novel catalysts for the synthesis of polyurethanes, represented by general formula (I) or (II), or compounds obtained by reacting a metal salt of the metals magnesium, calcium, yttrium, lanthanum, titanium, zirconium, manganese, iron, cobalt, zinc, aluminium, tin, comprising an anion from the group fluoride, chloride, bromide, sulphonate, trifluoromethanesulphonate, methanesulphonate, benzolsulphonate, para-toluenesulphonate, carboxy-C1-C10-alkyl, carboxy-C3-C10-cycloalkyl, carboxy- C2-C10-alkenyl, C1-C10-alkoxy, acetylacetonate, trifluoroacetlyacetonate or hexafluoroacetylacetonate, with N-heterocyclic compounds of general structure I; or with N-heterocyclic compounds of general structure II; or with N-heterocyclic compounds of general structure III.

专利号:US-2018142273-A1
优先权日:2015-04-15
标题 :Iterative platform for the synthesis of alpha functionalized products
发明人:GONZALEZ RAMON; CLOMBURG JAMES M; CHEONG SEOKJUNG
权利人:UNIV RICE WILLIAM M
摘要:The use of microorganisms to make alpha-functionalized chemicals and fuels, (e.g. alpha-functionalized carboxylic acids, alcohols, hydrocarbons, amines, and their beta-, and omega-functionalized derivatives), by utilizing an iterative carbon chain elongation pathway that uses functionalized extender units. The core enzymes in the pathway include thiolase, dehydrogenase, dehydratase and reductase. Native or engineered thiolases catalyze the condensation of either unsubstituted or functionalized acyl-CoA primers with an alpha-functionalized acetyl-CoA as the extender unit to generate alpha-functionalized β-keto acyl-CoA. Dehydrogenase converts alpha-functionalized β-keto acyl-CoA to alpha-functionalized β-hydroxy acyl-CoA. Dehydratase converts alpha-functionalized β-hydroxy acyl-CoA to alpha-functionalized enoyl-CoA. Reductase converts alpha-functionalized enoyl-CoA to alpha-functionalized acyl-CoA. The platform can be operated in an iterative manner (i.e. multiple turns) by using the resulting alpha-functionalized acyl-CoA as primer and the aforementioned alpha-functionalized extender unit in subsequent turns of the cycle. Termination pathways acting on any of the four alpha-functionalized CoA thioester intermediates terminate the platform and generate various alpha-functionalized carboxylic acids, alcohols and amines with different β-reduction degree.

专利号:WO-2008103866-A1
优先权日:2007-02-22
标题 :Synthesis of indoles
发明人:TALLEY JOHN JEFFREY; RENZE JUERGEN T
权利人:MICROBIA INC; TALLEY JOHN JEFFREY; RENZE JUERGEN T
摘要:Method for preparing indoles, including methods that permit high yield production of particular compounds, are described.

专利号:US-11697830-B2
优先权日:2015-04-15
标 题 :Iterative platform for the synthesis of alpha functionalized products
发明人:GONZALEZ RAMON; CLOMBURG JAMES M; CHEONG SEOKJUNG
权利人:GONZALEZ RAMON; CLOMBURG JAMES M; CHEONG SEOKJUNG
摘要:The use of microorganisms to make alpha-functionalized chemicals and fuels, (e.g. alpha-functionalized carboxylic acids, alcohols, hydrocarbons, amines, and their beta-, and omega-functionalized derivatives), by utilizing an iterative carbon chain elongation pathway that uses functionalized extender units. The core enzymes in the pathway include thiolase, dehydrogenase, dehydratase and reductase. Native or engineered thiolases catalyze the condensation of either unsubstituted or functionalized acyl-CoA primers with an alpha-functionalized acetyl-CoA as the extender unit to generate alpha-functionalized β-keto acyl-CoA. Dehydrogenase converts alpha-functionalized β-keto acyl-CoA to alpha-functionalized β-hydroxy acyl-CoA. Dehydratase converts alpha-functionalized β-hydroxy acyl-CoA to alpha-functionalized enoyl-CoA. Reductase converts alpha-functionalized enoyl-CoA to alpha-functionalized acyl-CoA. The platform can be operated in an iterative manner (i.e. multiple turns) by using the resulting alpha-functionalized acyl-CoA as primer and the aforementioned alpha-functionalized extender unit in subsequent turns of the cycle. Termination pathways acting on any of the four alpha-functionalized CoA thioester intermediates terminate the platform and generate various alpha-functionalized carboxylic acids, alcohols and amines with different β-reduction degree.
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16957-70-3
trans-2-Methyl-2-pentenoic acid
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主要参考文献

[参考文献]: Li W, Et Al. A Concise Formal Total Synthesis Of Lactimidomycin. Chem Commun (Camb). 2015 May 21;51(41):8634-6.
[参考文献]: Shuai Tan, Et Al. In Situ Atr-Ir Study Of Prochiral 2-Methyl-2-Pentenoic Acid Adsorption On Al2O3 And Pd/al2O3. Phys Chem Chem Phys. 2011 Nov 21;13(43):19573-9.

合成参考文献


摘要:Troll, T., Science of Synthesis, (2007) 35, 445.
摘要:Baader, W. J.; Bastos, E. L., Science of Synthesis, (2009) 38, 359.
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