CAS: 14941-08-3; (2S)-Poncirin
该化合物是主要在柑橘水果,特别是松树三叶花植物的叶子和水果中发现的花草甘蓝,其特点是化学结构,由附着糖糖的花粉骨组成,典型的香味.该化合物展示了各种生物活动,包括抗氧化剂,抗炎和潜在的抗癌特性,使其对药理研究感兴趣.蓬西林还因其在植物防御机制中的作用而著称,并可能有助于柑橘产品的口味和芳香特征.它在水中的溶液有限,可能影响其生物利用率和生物系统的效率.此外,蓬西林还因其潜在的健康利益,包括其调节代谢过程的能力及其对心血管健康的影响而进行了研究.随着研究的继续进行,其治疗应用和作用的全部范围仍在探索之中.
- 英文名称(2S)-Poncirin
- 中文名称枸橘苷
- IUPAC名称(S)-7-(((2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-5-hydroxy-2-(4-methoxyphenyl)chroman-4-one
- 其它别名ISOSAKURANETIN-7-NEOHESPERIDOSIDE; ISOSAKURANETIN-7-O-NEOHESPERIDOSID; ISOSAKURANETIN-7-O-NEOHESPERIDOSIDE; PONCIRIN; (S)-5,7-DIHYDROXY-4'-METHOXYFLAVANONE-7-[2-O-(ALPHA-L-RHAMNOPYRANOSYL)-BETA-D-GLUCOPYRANOSIDE]; (s)-5,7-dihydroxy-4'-methoxyflavanone-7-[2-o-(α-l-rhamnopyranosyl)-β-d-glucopyranoside]; PONCIRIN WITH HPLC
- CAS编号14941-08-3
- MFCD编号:MFCD23380546
- EINECS号:239-020-1
- FDA UNII编号:8MUY4P95B4
- 分子式:C28H34O14分子量:594.57
- 产品CID: 720134
- 产品分类生物化工 → 中草药成分
物理性质
- 熔点210 °C
- 沸点900.1±65.0 °C at 760 mmHg
- 闪点296.5±27.8 °C
- 密度1.6±0.1 g/cm3
- pKa:7.15±0.40(预测)
- PSA:214.06
- LogP:3.39
- 折射率1.678
- 蒸汽压0.0±0.3 mmHg at 25°C
- 溶解性溶于甲烷
- 外观形态固体-粉末
- 储存条件Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
- 产品应用该化合物是一种在P. TRIFOLIATA中发现的浮质甘油,具有多种生物活动,抑制了在浓度在5至25微克/毫升之间使用SGC-7901胃癌细胞的生长.PONCIRIN抑制了LPS引起的NF-BDNA结合活动,以及在RAW 264.7细胞中生产一氧化氮和PROSTAGLANDIN E2.PONSCIRIN在剂量为50和100毫克/千克的剂量下施用HCL/乙醇引起的胃胃炎时,减少了气态溃素降解指数.
MSDS等安全信息
上下游产品
CAS号23643-72-3 poncirin chalcone | CAS号123-11-5 4-甲氧基苯甲醛; 对甲氧基苯... | CAS号23643-71-2 2,6-dihydroxy-4...合成工艺路线路线简述
📜Phloroacetophenone 4'-O-β-Neohesperidoside置于吡啶,氢氧化钾体系中,用 乙醇,水 用作溶剂,化学反应生成枸橘苷
参考文献:花青素-类黄酮复合物形成的结构方面及其在植物颜色中的作用
标题:花青素-类黄酮复合物形成的结构方面及其在植物颜色中的作用
摘要:摘要 黄酮类化合物与花青素形成复合物,导致吸光度增加和后者可见光吸收最大值的红移,主要是基于花青素脱水碱的羰基与花青素的芳香羟基之间形成氢键.形成复合物的类黄酮.类黄酮分子中的羟基数量越多,复合物的形成就越强.类黄酮分子中3-羟基的存在对复合物形成能力影响不大.形成络合物的黄酮类化合物的糖取代基的性质对反应没有影响.黄酮类化合物的 5-羟基通过分子内氢键与 4-羰基强结合,不参与复合物的形成.类黄酮分子中最重要的羟基是位于 7 位的羟基.杂环中c2c3的不饱和度是形成配合物的重要因素.仅类黄酮系统中的芳香羟基不能解释所有的复合物形成能力,表明静电力和构型或空间效应的额外参与.
Doi:10.1016/0031-9422(81)85111-4
海关参考信息
- 2902600000-乙苯
2905122000-异丙醇
2905310000-1,2-乙二醇
2905320000-1,2-丙二醇 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-11773128-B2
优先权日:2019-03-28
标题 :Electrocatalytic synthesis of dihydrochalcones
发明人：REDKO MIKHAIL; SAFFRON CHRISTOPHER M; JACKSON JAMES E
权利人:UNIV MICHIGAN STATE
摘要:The disclosure relates to methods of forming a dihydrochalcone using electrocatalytic dehydrogenation. In particular, the disclosure relates to methods of forming a dihydrochalcone electrocatalytically hydrogenating (ECH) a reactant compound over a catalytic cathode in a reaction medium having a non-alkaline pH value, thereby forming a dihydrochalcone product; wherein the reactant compound has a structure according to Formula (I). The method can be used to prepare dihydrochalcone sweeteners, such as, for example, naringin dihydrochalcone and neohesperidin dihydrochalcone.
专利号:US-12036300-B2
优先权日:2021-03-31
标题:Methods and compositions for improving skin
发明人：LIAO I-CHIEN; BRIEVA PATRICIA; JUCHAUX FRANCK; BOUEZ CHARBEL; ZHENG QIAN; QIAN KUN
权利人:OREAL
摘要:A method for managing skin tone comprising reducing the synthesis of melanin by applying a skin treatment composition to skin. The skin treatment composition may include about 0.1 to about 25 wt. % of acetyl trifluoromethylphenyl valylglycine; about 0.5 to about 30 wt. % of a polyol; about 0.1 to about 30 wt. % of a silicone, fatty compound, or a mixtures thereof, wherein the skin treatment composition is an emulsion, and all weight percentages are based on the total weight of the skin treatment composition.
专利号:CN-119331888-A
优先权日:2024-10-10
标题:Polygonatum cyrtonema PcF3H gene and application thereof in promotion of synthesis of dihydroflavonoid compounds and catalysis of naringenin hydroxylation
专利号:WO-2020198578-A1
优先权日:2019-03-28
标 题:Electrocatalytic synthesis of dihydrochalcones
专利号:US-2022089630-A1
优先权日:2019-03-28
标 题 :Electrocatalytic synthesis of dihydrochalcones
专利号:EP-3947781-A1
优先权日:2019-03-28
标题 :Electrocatalytic synthesis of dihydrochalcones
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
1: Gandhi GR, Vasconcelos ABS, Wu DT, Li HB, Antony PJ, Li H, Geng F, Gurgel RQ, Narain N, Gan RY. Citrus Flavonoids as Promising Phytochemicals Targeting Diabetes and Related Complications: A Systematic Review of In Vitro and In Vivo Studies. Nutrients. 2020 Sep 23;12(10):E2907. doi: 10.3390/nu12102907.
262:113178. doi: 10.1016/j.jep.2020.113178. Epub 2020 Jul 28.
102:104061. doi: 10.1016/j.bioorg.2020.104061. Epub 2020 Jun 30. 20(1):115. doi: 10.1186/s12906-020-02906-7.
合成参考文献
参考文献:10.1002/ptr.6798
摘要:Zhao L, Zhang W, Zhang F. Poncirin downregulates
参考文献:10.1016/j.ejphar.2022.174759
摘要:Li B, Chen T, Hu W, Wang Z, Wu J, Zhou Q, Li P. Poncirin ameliorates cardiac ischemia-reperfusion injury by activating PI3K/AKT/PGC-1α signaling. Eur J Pharmacol. 2022 Feb 15;917():174759. doi: 10.1016/j.ejphar.2022.174759.
参考文献:10.1021/np060217s
摘要:Nakagawa H, Takaishi Y, Tanaka N, Tsuchiya K, Shibata H, Higuti T. Chemical Constituents from the Peels of Citrus sudachi. J. Nat. Prod. 2006 Aug 01;69(8):1177–9. doi: 10.1021/np060217s.
📝 需求与反馈
尽可能描述清楚需求与问题信息
