CAS: 621-71-6; Propane-1,2,3-Triyl Tris(Decanoate)

该化合物是一种化学化合物,被归类为中链三氟酸(MCT),由甘蓝醇和三碳酸(decanoic)分子组成,在室温下,三氯丙烯是一种无色的淡黄色液体,以其低粘度和相对低的熔点闻名,在有机溶剂中溶解,但在水中溶解性有限,该化合物经常用于食品,化妆品和药物应用,因其乳胶特性和吸收某些营养素的能力而经常用于食品,化妆品和药物应用中.Tricaprin因其潜在的健康惠益而得到承认,特别是在提供快速能源方面,因为中链脂肪酸的代谢值不同于长链脂肪酸.此外,它具有抗微生物特性,因此在各种配方中有用.安全评估表明,三氯丙丙丙烯在适当使用时一般被视为安全,尽管个别敏感度可能有所不同.

结构式图片

上下游产品

CAS号334-48-5 正癸酸 | CAS号56-81-5 甘油 | CAS号112-13-0 癸酰氯 | CAS号110-38-3 癸酸乙酯 | CAS号112-30-1 正癸醇 | CAS号56-81-5 甘油 | CAS号110-42-9 癸酸甲酯 | CAS号3376-48-5 2-O-Decanoylglycerol | CAS号112-12-9 2-十一酮; 甲基壬基甲酮

合成工艺路线路线简述

  • 合成目标产物 Tricaprin 主要起始原料 Decanoyl Chloride And Glycerol
  • (文献来源)合成步骤主要原料 Decanoyl Chloride 和 Glycerol
📜正癸酸,甘油置于tetrabutoxytitanium体系中,用 环己烷 作为反应溶剂,化学反应生成 三癸酸甘油酯
参考文献:一种甘油基酯类增塑剂及其制备方法和无毒环保聚氯乙烯
标题:一种甘油基酯类增塑剂及其制备方法和无毒环保聚氯乙烯
摘要:本申请涉及塑料增塑剂的技术领域,更具体地说,它涉及一种甘油基酯类增塑剂及其制备方法和无毒环保聚氯乙烯.一种甘油基酯类增塑剂,由包括以下重量份的原料制成:19‑21份甘油,70‑145份单元酸,3.5‑8.5份环己烷以及0.18‑0.90份钛酸四正丁酯.其制备方法为:(1)预准备:准备原料;(2)酯化反应:混合原料并二次加热;(3)后处理:脱酸干燥.本申请的甘油基酯类增塑剂具有环保无毒,提升聚氯乙烯的力学性能和耐迁移性能的效果.

海关参考信息

专利信息


专利号:US-7598291-B2
优先权日:2004-09-02
标题 :Methods and compositions for enhancing collagen and proteoglycan synthesis in the skin
发明人:NIMNI MARCEL; HAN BO
权利人:NIMNI MARCEL; HAN BO
摘要:A composition for application to the skin can stimulate the in vivo synthesis of collagen and proteoglycans and improve the appearance of the skin, increasing its elasticity and fullness. In general, a composition according to the present invention comprises: (1) an antioxidant compound in a quantity sufficient to enhance collagen synthesis in the skin; (2) an organic penetrant in which the antioxidant compound is soluble in a sufficient quantity that a concentration of the antioxidant compound sufficient to enhance collagen synthesis can be applied topically and penetrate the skin; (3) a mixture of essential amino acids; (4) a supplemental source of sulfur; and (5) a topical pharmaceutically acceptable carrier. The antioxidant compound can be lipoic acid, a lipoic acid analogue or derivative, a bioflavonoid, a constituent of ginkgo, or an isoflavone. The organic penetrant is preferably benzyl alcohol. Other ingredients, such as esters of tocopherol and ascorbic acid, can be included.

专利号:US-2010160244-A1
优先权日:2004-09-02
标 题 :Methods and compositions for enhancing collagen, proteoglycan, and glutathione synthesis in the skin
发明人:NIMNI MARCEL; HAN BO
权利人:NIMNI MARCEL; HAN BO
摘要:A composition for application to the skin can stimulate the in vivo synthesis of collagen and proteoglycans and improve the appearance of the skin, increasing its elasticity and fullness. In general, a composition according to the present invention comprises: (1) an antioxidant compound in a quantity sufficient to enhance collagen synthesis in the skin; (2) an organic penetrant in which the antioxidant compound is soluble in a sufficient quantity that a concentration of the antioxidant compound sufficient to enhance collagen synthesis can be applied topically and penetrate the skin; (3) a mixture of essential amino acids or hydrolyzed whey protein; (4) a supplemental source of sulfur; and (5) a topical pharmaceutically acceptable carrier. The antioxidant compound can be lipoic acid or a lipoic acid analogue or derivative. The organic penetrant is preferably benzyl alcohol. Other ingredients, such as esters of tocopherol and ascorbic acid, can be included.

专利号:US-2005112158-A1
优先权日:2003-11-17
标 题 :Method for synthesis of silylated ascorbic acid derivatives
发明人:TERRY W L JR; LEGROW GARY E; LITTAU CHERYL
权利人:CLARIANT INTERNATINONAL LTD
摘要:A compound of Formula (I), as defined in the specification, and a method for its synthesis. The method includes providing an inert environment, minimizing exposure of the reaction environment to visible light and reacting ascorbic acid with solvent and a compound of the Formula (II), as defined in the specification. The method of the present invention produces increased yields and a compound having increased stability and the same or greater bioactivity than ascorbic acid. The compound formed by the method of the present invention is capable for use in anhydrous cosmetic, dermatological and pharmaceutical compositions as an active agent for combating aging of the skin and improving its aesthetic appearance.

专利号:US-9982005-B2
优先权日:2013-04-04
标 题 :Macrolides and methods of their preparation and use
发明人:MYERS ANDREW G; SEIPLE IAN BASS; ZHANG ZIYANG
权利人:HARVARD COLLEGE
摘要:Provided herein are methods of preparing macrolides by the coupling of an eastern and western half, followed by macrocyclization, to provide macrolides, including both known and novel macrolides. Intermediates in the synthesis of macrolides including the eastern and western halves are also provided. Pharmaceutical compositions and methods of treating infectious diseases and inflammatory conditions using the inventive macrolides are also provided. A general diastereoselective aldol methodology used in the synthesis of the western half is further provided.

专利号:US-2012094919-A1
优先权日:2009-03-16
标题 :Use of tripeptides
发明人:GRAEUB REMO; HEIDL MARC; IMFELD DOMINIK; MUELLER EIKE; WIKSTROEM PETER; ZIEGLER HUGO
权利人:GRAEUB REMO; HEIDL MARC; IMFELD DOMINIK; MUELLER EIKE; WIKSTROEM PETER; ZIEGLER HUGO
摘要:The present invention relates to the use of tripeptide derivatives for tightening, firming and/or moisturizing skin. Furthermore, the invention relates to a method for stimulating the synthesis of glycosaminoglycans containing a D-glucosamine and/or N-acetyl-D-glucosamine residue and/or proteoglycans by fibroblasts and/or keratinocytes such as in particular the synthesis of Hyaluronic acid and/or of the proteoglycans Decorin and/or Lumican.

专利号:EP-1779900-B1
优先权日:2005-10-29
标 题 :Cosmetic or dermatological composition for prevention of light-induced aging
发明人:NEUFANG HARTMUT; TILL MARTINA
权利人:APOTHEKER WALTER BOUHON GMBH
摘要:Use of a composition (I) comprising vitamin A (0.02-0.09 wt.%), phytosterol (0.1-3 wt.%), vitamin E (0.5-3 wt.%) and their biochemical precursors or derivatives, for the production of cosmetic or dermatological preparation for the inhibition of a light-induced gene expression of the synthesis of a collagenase in the skin. An independent claim is included for the cosmetic or dermatological preparation comprising (I), urea (1-4 wt.%), caprylic/capric acid triglyceride (caprylic/capric triglyceride according to INCI standard), lipids, consistency agents, emulsifying agents, polymers, perfumes, preservatives and water. ACTIVITY : Dermatological. MECHANISM OF ACTION : Gene expression of synthesis of collagenase Inhibitor.

供应商参考报价(招募中)

品牌试剂参考报价(招募中)

📌 第三方产品分析报告

✅ COA系统入驻 | 共享模式

主要参考文献


1: St-Pierre V, Vandenberghe C, Lowry CM, Fortier M, Castellano CA, Wagner R, Cunnane SC. Plasma Ketone and Medium Chain Fatty Acid Response in Humans Consuming Different Medium Chain Triglycerides During a Metabolic Study Day. Front Nutr. 2019 Apr 16;6:46. doi: 10.3389/fnut.2019.00046. eCollection 2019.
2: Suzuki A, Yamaguchi S, Li M, Hara Y, Miyauchi H, Ikeda Y, Zhang B, Higashi M, Ikeda Y, Takagi A, Nagasaka H, Kobayashi K, Magata Y, Aoyama T, Hirano KI. Tricaprin Rescues Myocardial Abnormality in a Mouse Model of Triglyceride Deposit Cardiomyovasculopathy. J Oleo Sci. 2018 Aug 1;67(8):983-989. doi: 10.5650/jos.ess18037. Epub 2018 Jul 17. doi: 10.2116/analsci.33.1297. doi: 10.5650/jos.ess16143. Epub 2017 May 17. doi: 10.3945/cdn.116.000257. eCollection 2017 Apr.
6: Meksiarun P, Andriana BB, Matsuyoshi H, Sato H. Non-invasive Quantitative Analysis of Specific Fat Accumulation in Subcutaneous Adipose Tissues using Raman Spectroscopy. Sci Rep. 2016 Nov 15;6:37068. doi: 10.1038/srep37068.

合成参考文献


摘要:S13 | EUCOSMETICS | Combined Inventory of Ingredients Employed in Cosmetic Products (2000) and Revised Inventory (2006) | DOI:10.5281/zenodo.2624118
摘要:Final Report 12/2017 Available from CIR
摘要:International Journal of Toxicology 20(suppl 4):61-94, 2001
参考文献:10.1046/j.1365-2362.2002.00959.x
摘要:Wanten GJ, Janssen FP, Naber AH. Saturated triglycerides and fatty acids activate neutrophils depending on carbon chain-length. Eur J Clin Invest. 2002 Apr;32(4):285–9. doi: 10.1046/j.1365-2362.2002.00959.x.
参考文献:10.1016/j.pep.2006.04.015
摘要:Sulong MR, Zaliha Raja Abd. Rahman RN, Salleh AB, Basri M. A novel organic solvent tolerant lipase from Bacillus sphaericus 205y: Extracellular expression of a novel OST-lipase gene. Protein Expression and Purification. 2006 Oct;49(2):190–5. doi: 10.1016/j.pep.2006.04.015.
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