参考标题:Copper-Catalyzed Synthesis And Anticancer Activity Evaluation Of Indolo[1,2-A]Quinoline Derivatives 作者:Adisak Thanetchaiyakup,Suparerk Borwornpinyo,Hassayaporn Rattanarat,Phongthon Kanjanasirirat,Kedchin Jearawuttanakul,Sawinee Seemakhan,Nutthawat Chuanopparat,Paiboon Ngernmeesri |发布日期:2021.10 摘要:A Simple And Effective One-Pot Synthesis Of Substituted Indolo[1,2-A]Quinolines Has Been Developed. The Desired Products Were Obtained In Up To 98% Yield When Substituted 2-Methyindoles Were Treated With 2-Iodobenzaldehyde In The Presence Of Cs2Co3, Cui And L-Proline. Our Mechanistic Study Confirmed That The Reaction Sequence Involved An Intermolecular Knoevenagel Reaction Followed By An Intramolecular
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