CAS: 3724-19-4; 3-Pyridinepropionic Acid

该化合物是一种有机化合物,其特征是附于一个丙诺酸酸协会的丙烯酸环;该化合物的特征是六人芳香环,内含一个氮原子,有助于其基本性和氢联结潜力;丙诺酸部分由于碳oxylic酸功能组而具有酸性,允许其参与各种化学反应,如酯化和恐吓;3-丙烯丙诺酸在室温中一般是白色的,非白色的固体,由于其极地功能组,在水和酒精等极地溶剂中可溶解;它可能展示生物活动,使其对制药研究和开发具有兴趣;此外,其结构特性允许其与生物系统互动,有可能影响代谢途径;

结构式图片

相似化合物

84199-98-4 2859-67-8 1256810-53-3

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ECHA物质C&L通报

上下游产品

CAS号19337-97-4 反-3(3-吡啶基)烯丙酸 | CAS号1126-74-5 3-(3-吡啶基)丙烯酸 | CAS号2859-67-8 3-吡啶丙醇 | CAS号626-55-1 3-溴吡啶 | CAS号3984-22-3 2-乙烯基-1,3-二氧戊环 | CAS号7440-44-0 活性炭 | CAS号81124-48-3 (E)-3-(吡啶-3-基)丙烯酸甲酯 | CAS号84199-98-4 3-(3-吡啶)丙酸甲酯 | CAS号64107-54-6 3-(吡啶-3-基)丙酸乙酯 | CAS号6283-81-4 3-氧代-3-(3-吡啶基)丙酸乙酯 | CAS号14757-41-6 3,4-二氢-1,6-萘啶-2... | CAS号84199-98-4 3-(3-吡啶)丙酸甲酯 | CAS号20173-24-4 3-(2-氨基乙基)吡啶 | CAS号6293-56-7 2-(3-吡啶基)乙醇 | CAS号100095-21-4 3-(1-methyl-2-o... | CAS号13623-84-2 1,2,3,4-四氢-1,6-萘啶 | CAS号84199-99-5 3-pyridin-3-ylp... | CAS号64107-54-6 3-(吡啶-3-基)丙酸乙酯

合成工艺路线路线简述

  • 合成目标产物 3-Pyridinepropionic Acid 主要起始原料 3-Pyridineacrylic Acid
  • (文献来源)合成步骤主要原料 3-Pyridineacrylic Acid
📜3-(3-吡啶)丙酸甲酯置于sodium Hydroxide体系中,用 甲醇 用作溶剂,化学反应生成3-(3-吡啶基)丙酸
参考文献:Discovery Of New C3Ar Ligands. Part 2: Amino-Piperidine Derivatives
标题:Discovery Of New C3Ar Ligands. Part 2: Amino-Piperidine Derivatives
摘要:The Synthesis And Structure-Activity Relationships Against The C3A Receptor Of A Series Of Substituted Aminopiperidine Derivatives Are Reported. Dmpk Properties And Functional Activities Of Selected Compounds Are Described. The Compounds Obtained Are The First Non-Arginine Ligands Of C3Ar. (C) 2007 Elsevier Ltd. All Rights Reserved.
Doi:10.1016/j.Bmcl.2007.04.023

海关参考信息

专利信息


专利号:US-9574189-B2
优先权日:2005-12-01
标题:Enzymatic encoding methods for efficient synthesis of large libraries
发明人:FRANCH THOMAS; LUNDORF MIKKEL DYBRO; JACOBSEN SØREN NYBOE; OLSEN EVA KAMPMANN; ANDERSEN ANNE LEE; HOLTMANN ANETTE; HANSEN ANDERS HOLM; SØRENSEN ANDERS MALLING; GOLDBECH ANNE; DE LEON DAEN; KALDOR DITTE KIEVSMOSE; SLØK FRANK ABILDGAARD; HUSEMOEN GITTE NYSTRUP; DOLBERG JOHANNES; Jensen Kim Birkebæ; PEDERSEN LENE; NØRREGAARD-MADSEN MADS; GODSKESEN MICHAEL ANDERS; GLAD SANNE SCHRØDER; NEVE SØREN; THISTED THOMAS; KRONBORG TINE TITILOLA AKINLEMINU; SAMS CHRISTIAN KLARNER; FELDING JAKOB; FRESKGÃ…RD PER-OLA; GOULIAEV ALEX HAAHR; PEDERSEN HENRIK
权利人:FRANCH THOMAS; LUNDORF MIKKEL DYBRO; JACOBSEN SØREN NYBOE; OLSEN EVA KAMPMANN; ANDERSEN ANNE LEE; HOLTMANN ANETTE; HANSEN ANDERS HOLM; SØRENSEN ANDERS MALLING; GOLDBECH ANNE; DE LEON DAEN; KALDOR DITTE KIEVSMOSE; SLØK FRANK ABILDGAARD; HUSEMOEN GITTE NYSTRUP; DOLBERG JOHANNES; Jensen Kim Birkebæ; PEDERSEN LENE; NØRREGAARD-MADSEN MADS; GODSKESEN MICHAEL ANDERS; GLAD SANNE SCHRØDER; NEVE SØREN; THISTED THOMAS; KRONBORG TINE TITILOLA AKINLEMINU; SAMS CHRISTIAN KLARNER; FELDING JAKOB; FRESKGÃ…RD PER-OLA; GOULIAEV ALEX HAAHR; PEDERSEN HENRIK; NUEVOLUTION AS
摘要:Disclosed is a method for obtaining a bifunctional complex comprising a molecule linked to a single stranded identifier oligonucleotide, wherein a nascent bifunctional complex comprising a chemical reaction site and a priming site for enzymatic addition of a tag is a) reacted at the chemical reaction site with one or more reactants, and b) reacted enzymatically at the priming site with one or more tag(s) identifying the reactant(s).

专利号:WO-2023137518-A1
优先权日:2022-01-21
标题 :Platinum complexes
发明人:ALDRICH-WRIGHT JANICE; GORDON CHRISTOPHER; DEO KRISHANT M; KHOURY ALEEN; MCGHIE BRONDWYN; APUTEN ANGELICO; PLATTEN-MENTI MARIA; RASHID FATIN; JURISINEC ASHLEY; SOLIMAN SARAH
权利人:WESTERN SYDNEY UNIV
摘要:The present disclosure relates to platinum complexes, and in particular platinum(II) and platinum(IV) complexes. The present disclosure also relates to synthesis of the platinum complexes, and to intermediates for the synthesis of the platinum complexes. The present disclosure also relates to methods and use of the platinum complexes for treating cancer.

专利号:US-9994558-B2
优先权日:2013-09-20
标题 :Multicyclic compounds and methods of using same
发明人:BALOGLU ERKAN; SHACHAM SHARON; SENAPEDIS WILLIAM; MCCAULEY DILARA; LANDESMAN YOSEF; GOLAN GALI; KALID ORI; SHECHTER SHARON
权利人:KARYOPHARM THERAPEUTICS INC
摘要:The invention generally relates to compounds represented by Structural Formula I: or a pharmaceutically acceptable salt thereof, wherein the variables are as defined and described herein. The invention also includes the synthesis and use of a compound of structural formula I, or a pharmaceutically acceptable salt or composition thereof, e.g., in treatment of cancer (e.g., mantle cell lymphoma), and other diseases and disorders (e.g., PAK-mediated, for example, PAK4-mediated, diseases and disorders).

专利号:US-11702652-B2
优先权日:2005-12-01
标题:Enzymatic encoding methods for efficient synthesis of large libraries

专利号:US-2009264300-A1
优先权日:2005-12-01
标题 :Enzymatic encoding methods for efficient synthesis of large libraries

专利号:EP-3515880-B1
优先权日:2017-03-17
标题:Methods and compositions for synthesis of encoded libraries
发明人:LI JIN; MORGAN BARRY A; Wan jinqiao; DOU DENGFENG; LIU GUANSAI; CHANG YONG; CHEN QIUXIA; WANG XING; XU YANSHAN; HU DONGYAN; LIU JIAN; CHENG XUEMIN
权利人:HITGEN INC

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品牌试剂参考报价(招募中)

📌 第三方产品分析报告

✅ COA系统入驻 | 共享模式

主要参考文献

[参考文献]: Andreas Lemmerer, Et Al. 3-(Pyridin-3-Yl)Propionic Acid. Acta Crystallogr Sect E Struct Rep Online. 2010 Dec 24;67(Pt 1):O215.

合成参考文献


摘要:de Figueiredo, R. M., Science of Synthesis: Knowledge Updates, (2024) 2, 265.
摘要:Panda, S. P.; Hota, S. K.; Jindal, A.; Murarka, S., Science of Synthesis: Base-Metal Catalysis, (2023) 2, 6.
参考文献:10.1007/s00253-006-0569-1
摘要:Yamada M, Okada Y, Yoshida T, Nagasawa T. Biotransformation of isoeugenol to vanillin by Pseudomonas putida IE27 cells. Applied Microbiology and Biotechnology. 2006 Aug 30;73(5):1025–30. doi: 10.1007/s00253-006-0569-1.
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