CAS: 3621-81-6; 2,5-Dichlorobenzooxazole

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4-氯-2-硝基苯酚置于platinum On Carbon 吡啶,氢气,氯体系中,用 甲醇,氯仿 用作溶剂,20.0 °C,379.22 Kpa 条件下,反应 1.5H,反应生成2,5-二氯苯并恶唑
参考文献: Piperidinecarboxamides As Mpges-1 Inhibitors[fr] Pipéridinecarboxamides En Tant Qu'Inhibiteurs De Mpges-1
标题: Piperidinecarboxamides As Mpges-1 Inhibitors[fr] Pipéridinecarboxamides En Tant Qu'Inhibiteurs De Mpges-1
摘要:本发明涉及式(I)的哌啶羧酰胺,它们在医学上作为mpges-1抑制剂用于治疗疼痛,包含它们的组合物,它们的制备过程以及用于这种过程的中间体.

专利信息

专利号:US-2016168138-A1
优先权日:2013-07-15
标题:Process for the preparation of suvorexant and intermediates useful in the synthesis of suvorexant
发明人：IQBAL JAVED; DAHANUKAR VILAS HARESHWAR; ORUGANTI SRINIVAS; KANDAGATLA BHASKAR
权利人:REDDY S LAB LIMTED DR
摘要:A novel processes for the preparation of suvorexant (formula I), its related compounds and its intermediates that are simple, economical and commercially viable. (I)

专利号:US-10030010-B2
优先权日:2014-08-04
标题:Route of synthesis for the preparation of suvorexant
发明人：BARTH ROLAND; HÖFERL-PRANTZ KATHRIN; RICHTER FRANK; WIDSCHWENTER GERHARD
权利人:SANDOZ AG
摘要:The present invention relates to a process for the preparation of a compound of formula (A), Further, the present invention relates to the respective compound (A) as such and to its use in the preparation of antifungal agent.

专利号:EP-3021851-A2
优先权日:2013-07-15
标 题 :Process for the preparation of suvorexant and intermediates useful in the synthesis of suvorexant

专利号:WO-2016020406-A1
优先权日:2014-08-04
标 题:Novel routes of synthesis for the preparation of suvorexant
发明人：BARTH ROLAND; HÖFERL-PRANTZ KATHRIN; RICHTER FRANK; WIDSCHWENTER GERHARD
权利人:SANDOZ AG
摘要:The present invention relates to a process for the preparation of a compound of formula (Ila') and (II) Further, the present invention relates to a compound of formula (Ila') and to a compound of formula (II) as well as all intermediates prepared during the process for the preparation of compound (Ila') and compound (II).

专利号:WO-2015008218-A2
优先权日:2013-07-15
标题:Process for the preparation of suvorexant and intermediates useful in the synthesis of suvorexant

专利号:EP-3177616-A1
优先权日:2014-08-04
标题 :Novel routes of synthesis for the preparation of suvorexant