Agc10H9N4O2S*2Ethylamine置于sodium Hydroxide,Mineral Acids,硝酸体系中,用 Sodium Hydroxide,水 用作溶剂,化学反应生成磺胺嘧啶银 参考文献:Metal Ammino Sulfa Compounds And Their Production 标题:Metal Ammino Sulfa Compounds And Their Production
专利信息
专利号:US-2022185854-A1 优先权日:2019-04-16 标题 :Tfeb mutants and their use in the treatment and/or prevention of disorders that require the induction of the cellular autophagy-lysosomal system 发明人:ROJAS-FERNANDEZ ALEJANDRO; BURGOS PATRICIA; GONZÃ?LEZ ALEXIS 权利人:UNIV AUSTRAL DE CHILE 摘要:The invention relates to constitutively active mutants of the transcription factor TFEB, which can mutate the lysine of one or both sites of positions 219 and 347; and/or also mutate the glutamic acid of one or both sites of positions 221 and 349, in order to eliminate the SUMOylation of the protein. By replacing these residues either from positions 219 and/or 221 and/or 347 and/or 349 by any other amino acid (such as arginine or alanine), it gives rise to a mutated TFEB, which more actively induces the expression of genes and protein synthesis of the lysosomal and autophagic pathway. Such as lysosomal storage disorders, neurodegenerative diseases, liver diseases, muscle diseases and metabolic diseases, and/or disorders or processes in the aging of the skin.
专利号:US-12251401-B2 优先权日:2018-08-24 标 题 :Synthesis and antimicrobial uses of dinuclear silver(I) pyrazolates 发明人:RAPTIS RAPHAEL G; CHAKRABORTY INDRANIL; KANDEL SHAMBHU 权利人:RAPTIS RAPHAEL G; CHAKRABORTY INDRANIL; KANDEL SHAMBHU; THE FLORIDA INTERNATIONAL UNIV BOARD OF TRUSTEES 摘要:Novel dinuclear silver(I) pyrazolido complexes and methods of synthesizing them are provided. Advantageously, the novel silver(I) pyrazolido complexes have excellent antimicrobial activity and methods of using said complexes to treat bacterial, fungal, and viral infections are also provided.
专利号:US-10443047-B2 优先权日:2014-05-01 标题 :Increasing cellular lipid production by increasing the activity of diacylglycerol acyltransferase and decreasing the activity of triacylglycerol lipase 发明人:TSAKRAKLIDES VASILIKI; BREVNOVA ELENA E 权利人:NOVOGY INC 摘要:Disclosed are methods and compositions for increasing the triacylglycerol content of a cell by up-regulating diacylglycerol acyltransferase and down-regulating triacylglycerol lipase. In some embodiments, a DGA1 protein is expressed and a native TGL3 gene is knocked out, thereby increasing the synthesis of triacylglycerol and decreasing its consumption, respectively.
专利号:US-2023364251-A1 优先权日:2020-08-06 标 题:Methods for the synthesis of protein-drug conjugates 发明人:BORCHARDT ALLEN; HUGHES ROBERT MICHAEL 权利人:CIDARA THERAPEUTICS INC 摘要:The present invention relates to intermediates and methods for synthesizing protein-drug conjugates that can be used for the treatment of diseases and related conditions.
专利号:US-6473536-B1 优先权日:1998-09-18 标题 :Image synthesis method, image synthesizer, and recording medium on which image synthesis program is recorded 发明人:CHIBA NAOKI; KANO HIROSHI 权利人:SANYO ELECTRIC CO 摘要:The present invention comprises the first step of dividing a first image and a second image for each triangular patch having three adjacent feature points as vertexes, and calculating a planer projective transform matrix for the triangular patch, and the second step of finding a coordinate value, on the first image, corresponding to each of pixels in each of the triangular patches, on the second image using the planer projective transform matrix calculated for the triangular patch, and finding a coordinate value, on the first image, corresponding to each of the pixels which does not belong to any of the triangular patches on the second image using a planer projective transform matrix calculated for the triangular patch closest to the pixel.
专利号:US-2007272664-A1 优先权日:2005-08-04 标题 :Carbon and Metal Nanomaterial Composition and Synthesis 发明人:SCHRODER KURT A; MARTIN KARL M 权利人:SCHRODER KURT A; MARTIN KARL M 摘要:The invention relates generally to nanopowder synthesis processes, and more particularly to the controlled use of a precursor material (such as a precursor gas) to assist in the formation of unagglomerated nanoparticles of the powder. It also relates to novel nanomaterials comprised of carbon and metals produced by the process along with the fundamental processes the novel nanomaterials enable.
摘要:Lancet., 340(126), 1992 摘要:Iyakuhin Kenkyu. Study of Medical Supplies., 13(637), 1982 摘要:United States Patent Document., #4020150 参考文献:10.1016/s0360-3016(01)01576-0 摘要:Szumacher E, Wighton A, Franssen E, Chow E, Tsao M, Ackerman I, Andersson L, Kim J, Wojcicka A, Ung Y, Sixel K, Hayter C. Phase II study assessing the effectiveness of Biafine cream as a prophylactic agent for radiation-induced acute skin toxicity to the breast in women undergoing radiotherapy with concomitant CMF chemotherapy. International Journal of Radiation Oncology*Biology*Physics. 2001 Sep;51(1):81–6. doi: 10.1016/s0360-3016(01)01576-0. 摘要:S76 | LUXPHARMA | Pharmaceuticals Marketed in Luxembourg | Pharmaceuticals marketed in Luxembourg, as published by d'Gesondheetskeess (CNS, la caisse nationale de sante, www.cns.lu), mapped by name to structures using CompTox by R. Singh et al. (2021) DOI:10.1021/acsenvironau.1c00008. List downloaded from https://cns.public.lu/en/legislations/textes-coordonnes/liste-med-comm.html. Dataset DOI:10.5281/zenodo.4587355