CAS: 189628-37-3; 5-Bromo-2-Chlorobenzaldehyde

上下游产品

CAS号149965-40-2 5-溴-2-氯苯甲醇 | CAS号251085-87-7 2-氯-5-溴苯甲酸甲酯 | CAS号842136-59-8 5-溴-2-氯-n-甲氧基-n... | CAS号21739-92-4 5-溴-2-氯苯甲酸

2-氯苯甲醛置于n-溴代丁二酰亚胺(Nbs),Silver Hexafluoroantimonate,C4H14B10Cl2S2体系中,用 硝基甲烷 用作溶剂,以65 %的收率获得5-溴-2-氯苯甲醛
参考文献:使用碳硼烷催化剂进行芳香卤化
标题:使用碳硼烷催化剂进行芳香卤化
摘要:卤代芳烃一直是现代有机化学领域中的一类重要化学品,因为卤化物官能团提供了许多可能的转化.使用分子卤素和路易斯/布朗斯台德酸活化剂的经典亲电芳香族卤化仍然是一种有前途的合成工具;然而,它存在操作困难,选择性低和官能团耐受性有限的问题.我们在此介绍基于碳硼烷的路易斯碱催化剂,用于使用卤代琥珀酰亚胺进行芳族卤化.所开发的反应体系易于应用于药物分子的后期功能化和多卤代芳烃的高效合成. β-碳硼烷支架最适合催化,并且通过装饰簇顶点进行可能的微调对于调节卤物种的电子性质以最大化催化性能非常重要.
Doi:10.1016/j.Chempr.2023.10.006

专利信息

专利号:US-7951827-B2
优先权日:2005-05-05
标 题:Synthesis and antiprotozoal activity of dicationic 3,5-diphenylisoxazoles
发明人：TIDWELL RICHARD R; BAKUNOVA SVETLANA M; BAKUNOV STANISLAV; PATRICK DONALD A
权利人:UNIV NORTH CAROLINA
摘要:Novel dicationic 3,5-diphenylisoxazole compounds are described. Synthetic routes to these novel compounds are provided. Several of the compounds displayed in vitro activity versus Trypanosoma brucei brucei and Plasmodium falciparum comparable to that of furamidine. A majority of the novel compounds also were less toxic to VERO cells than furamidine.

专利号:US-2006264487-A1
优先权日:2005-05-05
标 题:Synthesis and antiprotozoal activity of dicationic 3,5-diphenylisoxazoles

专利号:AU-2006201739-A1
优先权日:2005-05-05
标题:Synthesis and antiprotozoal activity of dicationic 3,5-diphenylisoxazoles

专利号:CN-113912487-B
优先权日:2021-11-23
标 题:A kind of synthesis method of 2,5-dihalogenated benzoic acid

专利号:EP-1719767-A1
优先权日:2005-05-05
标题:Synthesis and antiprotozoal activity of dicationic 3,5-diphenylisoxazoles

专利号:CA-2545778-A1
优先权日:2005-05-05
标 题:Synthesis and antiprotozoal activity of dicationic 3,5-diphenylisoxazoles