CAS: 75714-59-9; (R)-3,3'-Dibromo-2,2'-Dimethoxy-1,1'-Binaphthalene

上下游产品

2,2'-dimethoxy-1,1'-binaphthyl (R)-2,2'-dimethoxy-1,1'-dinaphthyl 3,3'-diphenyl-1,1'-bi-2-naphthol (R)-3,3'-dibromo-5,5',6,6',7,7',8,8'-°Ctahydro-[1,1'-binaphthalene]-2,2'-diol rac-3,3'-bis(2,4,6-triisopropylphenyl)-2,2'-dimethoxy-1,1'-dinaphthyl 3,3'-Bis-(3-bromo-2-hydroxy-5-methyl-phenyl)-[1,1']binaphthalenyl-2,2'-diol

(R)-1,1'-Bi-2-Naphthol置于正丁基锂,四甲基乙二胺,Sodium Hydroxide体系中,用 乙醚 作为反应溶剂,化学反应 8.5H,反应生成 (R)-3,3'-二溴-2,2'-二甲氧基-1,1'-联萘
参考文献:新型手性 (R)-3,3'-二取代 Binol-磷酸盐的合成,α-葡萄糖苷酶抑制和抗菌活性
标题:新型手性 (R)-3,3'-二取代 Binol-磷酸盐的合成,α-葡萄糖苷酶抑制和抗菌活性
摘要:摘要 制备了一类新的3,3'-二取代手性(R)-Binol衍生的磷酸衍生物.通过在 Suzuki-Miyaura 交叉偶联中使用 Pd/c 作为催化剂,使用未保护的 Binol 衍生物对合成方法进行了优化.已经对目标化合物进行了表征并测试了它们的 α-葡萄糖苷酶抑制和抗菌活性.
DOI:10.1134/s1070363222050206

专利信息

专利号:US-7517828-B2
优先权日:2003-04-25
标 题 :Chiral broensted acid catalyst for asymmetric synthesis and method of asymmetric synthesis with the catalyst
发明人：AKIYAMA TAKAHIKO
权利人:TOAGOSEI CO LTD
摘要:A compound usable as an asymmetric synthesis catalyst which can be easily synthesized without using any metal such as a lanthanoid group element; a method of asymmetric synthesis with the compound; and a chiral compound obtained by the asymmetric synthesis method. A Broensted acid is used as a catalyst in asymmetric synthesis, the chiral Broensted acid being represented by formula (1) below or formula (3) below. The asymmetric synthesis method employs the catalyst. Asymmetric synthesis with the catalyst gives a chiral compound.

专利号:US-2006276329-A1
优先权日:2003-04-25
标题:Asymmetric synthesis catalyst based on chiral brsnsted acid and method of asymmetric synthesis with the catalyst

专利号:EP-1623971-A1
优先权日:2003-04-25
标 题:Asymmetric-synthesis catalyst based on chiral broensted acid and method of asymmetric synthesis with the catalyst