CAS: 71239-85-5; Boc-2-Pal-Oh

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上下游产品

CAS号24424-99-5 二碳酸二叔丁酯 | CAS号37535-51-6 3-(2-吡啶基)-L-丙氨酸 | CAS号19814-60-9 diethyl 2-aceta... | CAS号74164-26-4 Nα-acetyl-β-(2-... | CAS号348619-79-4 2-Pyridinepropa... | CAS号37535-51-6 3-(2-吡啶基)-L-丙氨酸

Nα-Acetyl-β-(2-Pyridyl)-Dl-Alanine Ethyl Ester置于盐酸,Sodium Hydroxide体系中,用 水,叔丁醇 作为反应溶剂,化学反应 5.33H,反应生成 Boc-3-(2-吡啶基)-L-丙氨酸
参考文献:Hoes,C.; Raap,J.; Bloemhoff,W.,Recueil Des Travaux Chimiques Des Pays-Bas,1980,Vol. 99,# 3,P. 99-104
标题:Hoes,C.; Raap,J.; Bloemhoff,W.,Recueil Des Travaux Chimiques Des Pays-Bas,1980,Vol. 99,# 3,P. 99-104

专利信息

专利号:US-5378690-A
优先权日:1986-12-19
标题 :New renin-inhibitory oligopeptides, their preparation and their use
发明人：MORISAWA YASUHIRO; KATAOKA MITSURU; YABE YUICHIRO; IIJIMA YASUTERU; TAKAHAGI HIDEKUNI; KOIKE HIROYUKI; KOKUBU TATSUO; HIWADA KUNIO
权利人:SANKYO CO
摘要:Oligopeptides of formula (I): (I) where R1-R5 are various organic groups, and A represents a group of formula -NH- or -(CH2)n-, in which n represents an integer of from 1 to 3, have renin-inhibitory activity and are particularly suitable for oral administration. They may be prepared by condensing their component amino acids or lower oligopeptides using conventional peptide synthesis reactions.