CAS: 6873-13-8; (13As)-2,11-Dihydroxy-3,10-Dimethoxy-7-Methyl-5,6,7,8,13,13A-Hexahydroisoquinolino[3,2-A]Isoquinolin-7-Ium
该化合物是一家主要来自传统药用植物Phellodendron amurense树皮的藻类化合物,它展示了值得注意的生物活动,包括防炎,抗微生物和潜在的...
- 英文名称(13As)-2,11-Dihydroxy-3,10-Dimethoxy-7-Methyl-5,6,7,8,13,13A-Hexahydroisoquinolino[3,2-A]Isoquinolin-7-Ium
- 中文名称黄柏碱
- IUPAC名称(13aS)-2,11-dihydroxy-3,10-dimethoxy-7-methyl-5,6,7,8,13,13a-hexahydroisoquinolino[3,2-a]isoquinolin-7-ium
- 其它别名13aa-Berbinium,2,11-dihydroxy-3,10-dimethoxy-7-methyl- (8CI); 6H-Dibenzo[a,g]quinolizinium,5,8,13,13a-tetrahydro-2,11-dihydroxy-3,10-dimethoxy-7-methyl-, (7S-cis)-; (-)-Phellodendrine; N-Methylcoreximine; Phellodendrine
- CAS编号6873-13-8
- MFCD编号:MFCD11656144
- FDA UNII编号:AR68S526RB
- 分子式:C20H24NO4分子量:342.42
- 产品CID: 1680084
- 产品分类生物化工 → 中草药成分
物理性质
MSDS等安全信息
- 警示词warning
- 危险描述H303 May be harmful if swallowed+H313 Skin contact may be harmful+H333 Inhalation may be harmful to the body
- 防范说明P264Thoroughly clean after treatmentP280Wear protective gloves/Wear protective clothing/Wear protective goggles/Wear a protective maskP305If it enters the eyesP351Rinse carefully with water for a few minutesP338Remove the contact lens(If any)And easy to operate,Continue flushingP337If eye irritation persistsP313Obtain medical advice/care
- 安全声明H303May be harmful if swallowed+H313Skin contact may be harmful+H333Inhalation may be harmful to the body
合成工艺路线路线简述
海关参考信息
- 2902600000-乙苯
2905110000-甲醇
2907210001-间苯二酚
2908199090-其他酚的卤化衍生物 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
1: Liu H, Kong L, Cao D, Zhan X, Gao X, Sun H, Yan G, Zhao Q, Han Y, Wang X. Efficacy and mechanism of the Ermiao San series of formulas for rheumatoid arthritis based on Chinmedomics strategy. Phytomedicine. 2024 Jul 22;132:155903. doi: 10.1016/j.phymed.2024.155903. Epub ahead of print. 13(6):752. doi: 10.3390/antiox13060752.
4: Cheng C, Xu C, Zhou W, Xue L, Wang S, Zhai Q, Dai R. Integrated network pharmacology and serum metabonomics analysis to explore the potential mechanism of Anemarrhena asphodeloides Bunge-Phellodendron chinense Schneid herb pair in the treatment of benign prostatic hyperplasia. J Pharm Biomed Anal. 2024 Sep 15;248:116264. doi: 10.1016/j.jpba.2024.116264. Epub 2024 May 31.
2024:5535752. doi: 10.1155/2024/5535752.
合成参考文献
参考文献:10.1016/0021-9673(93)83021-j
摘要:Ying-Mei L, Shuenn-Jyi S. Determination of quaternary alkaloids from Phellodendri Cortex by capillary electrophoresis. Journal of Chromatography A. 1993 Mar;634(2):329–33. doi: 10.1016/0021-9673(93)83021-j.
参考文献:10.1076/phbi.37.1.77.6323
摘要:Bonté F, Dumas M, Saunois A, Meybeck A. Note Phospholipase A2 Inhibition by Alkaloid Compounds from Phellodendron amurense Bark. Pharmaceutical Biology. 1999 Jan;37(1):77–9. doi: 10.1076/phbi.37.1.77.6323.
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