CAS: 552-45-4; 1-(Chloromethyl)-2-Methylbenzene

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CAS号89-95-2 邻甲基苄醇 | CAS号50-00-0 甲醛 | CAS号108-88-3 甲苯 | CAS号95-47-6 邻二甲苯 | CAS号63246-55-9 (E)-5,5'-(cyclo... | CAS号88531-10-6 2-methyl-1-(tri... | CAS号932-31-0 邻甲苯基溴化镁 | CAS号612-14-6 邻苯二甲醇 | CAS号142066-41-9 [2-(chloromethy... | CAS号88-99-3 邻苯二甲酸 | CAS号10479-23-9 N-methyl-N-[(2-... | CAS号40851-62-5 邻甲苯乙酸甲酯 | CAS号5321-47-1 1-(2-甲基苄基)哌嗪 | CAS号40291-39-2 邻甲苯乙酸乙酯 | CAS号92614-55-6 2-甲基苯基甲烷磺酰氯 | CAS号95-47-6 邻二甲苯 | CAS号589-18-4 4-甲基苄醇 | CAS号952-80-7 1,2-二邻甲苯基乙烷 | CAS号113312-69-9 1-(4-methylphen... | CAS号89-95-2 邻甲基苄醇

邻二甲苯置于三氟甲烷磺酰氯,Iron(Iii) Chloride Hexahydrate体系中,用 乙腈 作为反应溶剂,以93 %的收率获得产物邻甲基氯化苄
参考文献:光诱导 Fecl3 催化三氟甲磺酰氯选择性苄基 C−h 氯化
标题:光诱导 Fecl3 催化三氟甲磺酰氯选择性苄基 C−h 氯化
摘要:在这里,我们报道了一种光诱导fecl 3催化的苄基c−h氯化方法,具有显着的区域选择性,使得烷基苯能够在温和条件下使用三氟甲磺酰氯(Tfcl)作为氯源转化为多功能的苄基氯.dft 计算表明,使用 Tfcl 时,苄基 α−c−h 氯化的动力学偏好更加明显.
DOI:10.1002/adsc.202300672

专利信息

专利号:US-4304949-A
优先权日:1980-07-25
标 题:Synthesis of ortho-methyldiphenylmethane
发明人：ZWEIG ARNOLD; FISCHER ROBERT G
权利人:AMERICAN CYANAMID CO
摘要:A process for the preparation of ortho-methyldiphenylmethane, a compound useful as an intermediate in the synthesis of anthraquinone, using liquid hydrogen fluoride to catalyze the alkylation of benzene with alpha -chloro-o-xylene at temperatures from about -10 DEG C. to 10 DEG C.

专利号:US-7514465-B2
优先权日:2004-11-16
标题 :Synthesis of N2-(substituted arylmethyl)-3-(substituted phenyl)indazoles as novel anti-angiogenic agents
发明人：KUO SHENG-CHU; HUANG LI-JIAU; LEE FANG-YU; TENG CHE-MING; SHIH MEI-LING; CHEN HUA-SIN
权利人:YUNG SHIN PHARM IND CO LTD
摘要:Novel compounds of 2-(substituted arylmethyl)-3-(substituted phenyl)-2H-indazoles and 1-(substituted arylmethyl)-3-(substituted phenyl)-1H-indazoles are synthesized, and useful as anti-angiogenic agents.

专利号:US-5186864-A
优先权日:1989-10-13
标题:Synthesis of dielectric liquids by improved friedel-crafts condensation
发明人：COMMANDEUR RAYMOND; BERGER NOELLE; JAY PIERRE; KERVENNAL JACQUES
权利人:ATOCHEM
摘要:Dielectric liquids are prepared by (a) Friedel-Crafts condensing at least one aromatic halide with at least one aromatic compound in the presence of a catalytically effective amount of ferric chloride, and thereafter deliberately avoiding any downstream destruction/neutralization and/or washing of such ferric chloride catalyst, (b) optionally, removing unreacted reactants from the medium of reaction, and (c) recovering from such medium of reaction a purified dielectric liquid; the subject process is thus environmentally improved by avoiding the generation of aqueous solutions containing contaminating amounts of objectionable organic compounds.

专利号:US-11608349-B2
优先权日:2019-07-28
标 题:Preparation and application of mixed-ligand nickel(II) complex containing bisoxazoline-derived nitrogen heterocyclic carbene ligand and phosphite ligand
发明人：SUN HONGMEI
权利人:UNIV SOOCHOW
摘要:The invention discloses a mixed Ni(II) complex containing bisoxazoline-derived nitrogen heterocyclic carbene ligand and phosphite ligand and application thereof; the chemical formula of the mixed Ni(II) complex is Ni(NHC)[P(OR) 3 ]X 2 , wherein R is ethyl or isopropyl, X is bromine or chlorine, and NHC is a bisoxazoline-derived nitrogen heterocyclic carbene ligand. In the presence of magnesium shavings, the mixed Ni(II) complex containing bisoxazoline-derived nitrogen heterocyclic carbene ligand and phosphite ligand of the present invention can catalyze low-activity chlorinated aromatic hydrocarbons and fluorinated aromatic hydrocarbons with chlorinated benzyl compounds, respectively, reductive cross-coupling reaction at a single temperature, generating a diarylmethane compound in one step, providing a new method for the synthesis of diarylmethane compounds.

专利号:US-4246373-A
优先权日:1980-02-14
标 题 :Synthesis of substituted cyclopentadienes and cyclopentadiene-functionalized polymers
发明人：KENNEDY JOSEPH P; CASTNER KENNETH F
权利人:KENNEDY JOSEPH P; CASTNER KENNETH F
摘要:Aluminum cyclopentadienyl compounds can be used to synthesize a variety of organic molecules containing the cyclopentadiene group, e.g., substituted cyclopentadiene compounds, polymer molecules with cyclopentadiene pendant groups, and polymer molecules with cyclopentadiene terminal groups.

专利号:US-6753347-B2
优先权日:1999-06-28
标题:Intermediates for the synthesis of benzimidazole derivatives and a process for the preparation thereof
发明人：KISHI NAOYUKI; NAKAMURA YOSHITAKA; ABE NARUMI; TAKEBAYASHI TOYONORI
权利人:SANKYO CO
摘要:This invention provides a process for the preparation of a benzimidazole derivative (I) or a pharmaceutically acceptable salt thereof, n wherein R 1 is C 1 -C 6 alkyl, C 1 -C 6 alkoxyl, etc., R 2 is C 1 -C 6 alkyl, and R 3 is hydrogen or a protecting group, which exhibits excellent hyopoglycemic action, said process comprising condensation of an amine derivative (III) with a carboxylic acid derivatives (II) to afford a compound (IV), followed by cyclization of compound (IV) in the presence of an acid.