CAS: 41088-86-2; Boc-L-Homoserine

相似化合物

745011-75-0 1927-25-9 6027-21-0

上下游产品

CAS号672-15-1 L-高丝氨酸 | CAS号24424-99-5 二碳酸二叔丁酯 | CAS号59408-74-1 B°C-O-苄基-L-高丝氨酸 | CAS号77-78-1 硫酸二甲酯 | CAS号40856-59-5 B°C-L-高丝氨酸内酯 | CAS号7536-55-2 B°C-L-天冬酰胺 | CAS号1070-19-5 Carbonazidic ac... | CAS号59408-74-1 B°C-O-苄基-L-高丝氨酸 | CAS号40856-59-5 B°C-L-高丝氨酸内酯 | CAS号120042-11-7 N-[(1,1-二甲基乙氧基)...

Boc-L-天冬酰胺置于sodium,氯化铵体系中,用 氨 作为反应溶剂,化学反应生成 N-Boc-L-高丝氨酸
参考文献:肽化学中钠液氨还原过程中副产物的形成
标题:肽化学中钠液氨还原过程中副产物的形成
摘要:液态氨中通常过量的钠会还原受保护的模型肽,从而导致产生不希望的副产物.终点的通常公认的蓝色对于完全还原是不必要的.
DOI:10.1039/c39820000639

专利信息

专利号:WO-2012150292-A1
优先权日:2011-05-03
标题:Stereoselective synthesis of cis-4-methylsphingosine and derivatives thereof
发明人：ARENZ CHRISTOPH; PROKSCH DENNY
权利人:UNIV BERLIN HUMBOLDT; ARENZ CHRISTOPH; PROKSCH DENNY
摘要:The invention provides for synthesis of a (S-R) dihydroxy-amino-methylalkylene characterized by the general formula I, or its R-S diastereomer, wherein R1 is CH2OH or CH2-CH2OH, and R2 is C2 to C20 alkyl, whereby a compound characterized by the general formula II, with R3, R4 and R5 being protecting groups for amino and hydroxyl functions, respectively, is used as a starting material. The invention further provides novel intermediates for syntheses of, and analogues to, cis-4-methylsphingosine.

专利号:US-2010022767-A1
优先权日:2008-07-25
标题 :Development of a synthesis of syringolin a and b and derivatives thereof
发明人：KAISER MARKUS; CLERC JEROME
权利人:MAX PLANCK GESELLSCHAFT
摘要:The synthesis of syringolin A and B and derivatives thereof as well as to pharmaceutical compositions containing the syringolin A or B or derivatives thereof and the use of syringolin A and B and derivatives thereof for prophylaxis and treatment of cancer.

专利号:US-2024218014-A1
优先权日:2022-11-21
标 题:Synthesis of a cyclic peptide
发明人：BAUR PIUS BRUNO; CLEATOR EDWARD; DENIAU GILDAS; EISELE FRANK; FLÖGEL OLIVER; HUSTE ANJA; KEHL MARCEL ROMAN; LÖWENECK MARKUS; SILVA ROLANDO RAVELO; VORBERG RAFFAEL
权利人:JANSSEN PHARMACEUTICA NV
摘要:Processes for performing peptide synthesis, particularly for cyclic peptide synthesis are generally described. Reaction intermediates of the peptide synthesis are also described.

专利号:US-8138272-B2
优先权日:2006-05-22
标 题:Preparation of polymer conjugates of therapeutic, agricultural, and food additive compounds
发明人：KONRADI ANDREI W; SMITH JENIFER L
权利人:KONRADI ANDREI W; SMITH JENIFER L; ELAN PHARM INC
摘要:This invention provides an improved synthesis of polymer conjugates of formula (I), n nof agricultural, therapeutic, and food additive compounds. In particular, a process is described for the preparation of conjugates by treating primary or secondary alcohol substituents of active compounds with polymeric nucleophiles using “Mitsunobuâ€? or related reaction conditions.

专利号:US-2003232820-A1
优先权日:2001-08-29
标题:Method for synthesizing oxazinones
发明人：WOLFE SAUL; WILSON MARIE-CLAIRE; CHENG MING-HUEI
摘要:New methods and intermediates are discussed for the stereospecific synthesis of oxazinone compounds.

专利号:US-8076496-B2
优先权日:2000-03-16
标题:Chemoselective ligation
发明人：SAXON ELIANA; BERTOZZI CAROLYN RUTH
权利人:SAXON ELIANA; BERTOZZI CAROLYN RUTH; UNIV CALIFORNIA
摘要:The present invention features a chemoselective ligation reaction that can be carried out under physiological conditions. In general, the invention involves condensation of a specifically engineered phosphine, which can provide for formation of an amide bond between the two reactive partners resulting in a final product comprising a phosphine moiety, or which can be engineered to comprise a cleavable linker so that a substituent of the phosphine is transferred to the azide, releasing an oxidized phosphine byproduct and producing a native amide bond in the final product. The selectivity of the reaction and its compatibility with aqueous environments provides for its application in vivo (e.g., on the cell surface or intracellularly) and in vitro (e.g., synthesis of peptides and other polymers, production of modified (e.g., labeled) amino acids).