CAS: 3333-15-1; 2,3-Diphenylpropanoic Acid

该化合物是一种多用途有机化合物,其特点是芳香结构和酸性,广泛用于合成药品,农用化学品和材料科学,该化合物具有极好的溶性,稳定性和反应性,在各种化学反应中成为首选. 它独特的芳香结构有助于其高热稳定性和耐降解性,提高它的储存寿命和对复杂合成途径的适宜性.

结构式图片

物理性质

MSDS等安全信息

欧盟法规

ECHA物质C&L通报REACH预注册

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CAS号91-48-5 α-苯基肉桂酸 | CAS号91-47-4 苯可丁酸 | CAS号103-82-2 苯乙酸 | CAS号100-39-0 溴化苄 | CAS号103-80-0 苯乙酰氯 | CAS号104266-89-9 3-(1-oxo-2-phen... | CAS号100-52-7 苯甲醛

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    专利信息


    专利号:US-2005192265-A1
    优先权日:2003-03-20
    标 题:Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting beta-amyloid peptide release and/or its synthesis by use of such compounds
    发明人：THOMPSON RICHARD C; WILKIE STEPHEN; STACK DOUGLAS R; VANMETER ELDON E; SHI QING; BRITTON THOMAS C; AUDIA JAMES E; REEL JON K; MABRY THOMAS E; DRESSMAN BRUCE A; CWI CYNTHIA L; HENRY STEVEN S; MCDANIEL STACEY L; STUCKY RUSSELL D; PORTER WARREN J
    摘要:Disclosed are compounds which inhibit β-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions that include a compound which inhibits β-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.

    专利号:US-6906056-B2
    优先权日:1998-06-22
    标 题:Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds
    发明人：THOMPSON RICHARD C; WILKIE STEPHEN; STACK DOUGLAS R; VANMETER ELDON E; SHI QING; BRITTON THOMAS C; AUDIA JAMES E; REEL JON K; MABRY THOMAS E; DRESSMAN BRUCE A; CWI CYNTHIA L; HENRY STEVEN S; MCDANIEL STACEY L; STUCKY RUSSELL D; PORTER WARREN J
    权利人:LILLY CO ELI
    摘要:Disclosed are compounds which inhibit β-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions that include a compound which inhibits β-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.

    专利号:FR-2609474-A1
    优先权日:1987-01-09
    标 题:PROCESS FOR THE ELECTROCHEMICAL SYNTHESIS OF CARBOXYLIC ACIDS

    专利号:US-2004106598-A1
    优先权日:1998-06-22
    标 题:Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting Beta-amyloid peptide release and/or its synthesis by use of such compounds

    专利号:US-2005192269-A1
    优先权日:1998-06-22
    标 题:Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting beta-amyloid peptide release and/or its synthesis by use of such compounds

    专利号:US-2005267150-A1
    优先权日:1998-06-22
    标 题:Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting beta-amyloid peptide release and/or its synthesis by use of such compounds

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    合成参考文献


    摘要:Merino, P., Science of Synthesis, (2010) 45, 289.
    摘要:Eilbracht, P., Science of Synthesis, (2009) 48, 405.
    摘要:Tan, X.; Lv, H.; Zhang, X., Science of Synthesis: Catalytic Reduction in Organic Synthesis, (2017) 1, 43.
    摘要:Hudson, R.; Moores, A., Science of Synthesis: Catalytic Reduction in Organic Synthesis, (2017) 1, 72.
    摘要:Parmeggiani, F.; Galman, J. L.; Montgomery, S. L.; Turner, N. J., Science of Synthesis, (2019) , 400.
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