CAS: 2930-05-4; 2-((Benzyloxy)Methyl)Oxirane

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CAS号556-52-5 缩水甘油 | CAS号100-39-0 溴化苄 | CAS号14593-43-2 烯丙基苄基醚 | CAS号100-44-7 氯化苄 | CAS号106-89-8 环氧氯丙烷 | CAS号100-51-6 苯甲醇 | CAS号13991-52-1 1-苄氧基-3-氯-2-丙醇 | CAS号372-20-3 3-氟苯酚 | CAS号3132-64-7 环氧溴丙烷 | CAS号949-97-3 1-Benzylglycero... | CAS号90503-15-4 3-苄氧基-2-羟基-1-丙胺 | CAS号22323-82-6 (S)-(+)-甘油醇缩丙酮 | CAS号6972-79-8 1,3-二苄氧基-2-丙醇 | CAS号60656-87-3 苄氧基乙醛 | CAS号955124-65-9 (S)-1-(benzylox... | CAS号612-16-8 2-甲氧基苯甲醇 | CAS号102629-92-5 2-hydroxy-3-phe... | CAS号102956-89-8 1,3-bis(phenylm... | CAS号17325-85-8 (S)-(-)-3-苄氧基-1...

📜1-O-P-Toluolsulfonyl-3-O-Benzyl-Sn-Glycerol置于sodium Methylate体系中,用 N,N-二甲基甲酰胺 用作溶剂,化学反应 12.0H,以80%的收率获得苄基缩水甘油醚
参考文献:单和二取代的二乙烯基砜的一般路线:用于合成多官能环砜的无环迈克尔受体.
标题:单和二取代的二乙烯基砜的一般路线:用于合成多官能环砜的无环迈克尔受体.
摘要:使用容易获得的β-羟基磺酸酯衍生物形成亲核c-S键,可直接获得新的单取代和二取代的二乙烯基砜.我们的策略是使用硫代乙醇(hsch 2 Ch 2 Oh)及其类似物,例如原位生成的hsch 2 Ch(y)oh.该策略还允许合成修饰的二乙烯基砜,该二乙烯基砜与诸如碳水化合物的手性附属物连接.与1当量的伯胺的双-异亲核迈克尔加成反应提供了以其治疗应用而闻名的新一代s,S-二氧代硫吗啉衍生物.这些环状化合物中的一些的进一步合成操作导致了新的双环衍生物的合成.
Doi:10.1021/jo101877R

专利信息

专利号:US-8748660-B2
优先权日:2012-07-09
标题:Process for the synthesis of antiepileptic drug lacosamide
发明人：MURUGAN MUTHUKRISHNAN; MUJAHID MOHAMMAD; MAJUMDAR PRASHANT PRAMOD
权利人:MURUGAN MUTHUKRISHNAN; MUJAHID MOHAMMAD; MAJUMDAR PRASHANT PRAMOD; COUNCIL SCIENT IND RES
摘要:The present invention relates to the improved and efficient process for the synthesis of antiepileptic drug Lacosamide in high enantiopurity (>98% ee) and better yield. More particularly, the present invention relates to improved and efficient, cost effective process for synthesis of desired (R) isomer of Lacosamide starting from commercially available (S)-benzyl glycidyl ether.

专利号:WO-2023152730-A1
优先权日:2022-02-14
标题 :Amine-borane adducts in the synthesis of polyester and its copolymers using cyclic esters and compositions thereof
发明人：FENG XIAOSHUANG; LIU JINGJING; GNANOU YVES
权利人:UNIV KING ABDULLAH SCI & TECH
摘要:Embodiments of the present disclosure provide for the process of synthesis of polyester and its copolymers through (co)polymerization of cyclic esters and with other oxygenated monomers using amine-borane adduct. Embodiments of the present disclosure further describe the controlled anionic ring-opening polymerization of the cyclic compounds. Embodiments of the present disclosure also describe the polymerization of cyclic compounds using the synergistic effect of amines and thioureas. Embodiments of the present disclosure also describe compositions of polymers formed by the said process.

专利号:US-9284306-B2
优先权日:2012-05-11
标题 :(R)-Nifuratel, its use for the treatment of infections and synthesis of (R) and (S)-Nifuratel
发明人：GAGLIARDI STEFANIA; CONSONNI ALESSANDRA; MAILLAND FEDERICO; BULGHERONI ANNA
权利人:POLICHEM SA
摘要:(R)-Nifuratel is disclosed together with its use as bactericide and bacteriostatic agent as well as the pharmaceutical compositions containing the same; (R)-nifuratel has been surprisingly found to possess a better antimicrobial profile than either nifuratel racemate or (S)-nifuratel. A new procedure for the synthesis of both (R)-Nifuratel and (S)-Nifuratel is also disclosed.

专利号:US-5591852-A
优先权日:1990-08-10
标题 :Process for the preparation of nucleotides
发明人：VEMISHETTI PURUSHOTHAM; BRODFUEHRER PAUL R; HOWELL HENRY G; SAPINO JR CHESTER
权利人:ACAD OF SCIENCE CZECH REPUBLIC; REGA STICHTING
摘要:The present invention relates to a novel and economical process for the synthesis of HPMP-substituted nucleotide antiviral compounds. Also disclosed are novel intermediates produced in the process for the preparation of HPMPC.

专利号:US-2025303400-A1
优先权日:2022-05-27
标题 :Catalyst for organic synthesis use, and method for producing organic compound
发明人：KATO AYUMU; NAKAMURA SHINJI
权利人:ORGANO CORP
摘要:Provided are: a catalyst for organic synthesis use, which has a high catalytic activity, can be easily separated by solid/liquid separation from a reaction system, and enables highly efficient synthesis of an organic compound; and a method for producing an organic compound using the catalyst. This catalyst for organic synthesis use includes an anionic exchange resin that has a hydrohalic acid salt of a tertiary amino group as an ion exchange group. This method for producing an organic compound uses, as a catalyst, an anionic exchange resin that has a hydrohalic acid salt of a tertiary amino group as an ion exchange group.

专利号:US-2006089405-A1
优先权日:2004-10-21
标 题 :Asymmetric synthesis of dihydrobenzofuran derivatives
发明人：ZHOU DAHUI; STACK GARY P; GONTCHAROV ALEXANDER V
权利人:WYETH CORP
摘要:This invention concerns a process for the preparation of benzofuran derivatives. In some aspects, these compounds are of formula I: n n nwherein each of R 1 , R 2 , R 3 , and R 4 is as defined herein.