CAS: 26121-56-2; 10-Hydroxy-2-Methoxy-3,3A1,8,11A-Tetramethyl-3A,4,6A,7,7A,8,9,10,11A,11B-Decahydrodibenzo[de,G]Chromene-1,5,11(3A1H)-Trione

上下游产品

picrasinoside-A Isopicrasin B quassin 2,12-Dimethoxy-1β-hydroxy-2,12-picradiene-11,16-dione 16-ethylene acetal2,3-didehydropicrasin B (-)-picrasin B acetate 2-picrasin BΔ2-picrasin B quassin

📜Isopicrasin B置于1,8-二氮杂双环[5.4.0]十一碳-7-烯体系中,用 甲醇 用作溶剂,以44%的收率获得苦树素b
参考文献:A Partial Synthesis Of (-)-Shinjulactone H From (+)-Quassin
标题:A Partial Synthesis Of (-)-Shinjulactone H From (+)-Quassin
摘要:A Partial Synthesis Of (-)-Shinjulactone H (3) From (+)-Quassin (1) Required The Selective Manipulation Of Two Similar O-Methyldiosphenol Groups. Protection Of The Delta-Lactone In 1 As An Ortho Ester,Selective Reduction Of The C-1 Carbonyl Group,Hydrolysis Of The Resulting Enol Ether In The A Ring,And Catalytic Hydrogenation Of The O-Methyldiosphenol In The C Ring Delivered An Intermediate Possessing An Alpha-Ketol Group In The A Ring And An Alpha-Methoxy Ketone Group In The C Ring. Demethylation And Concomitant Alpha-Ketol Tautomerization In The A Ring Delivered (-)-Shinjulactone H (3).
Doi:10.1021/jo00034A008