CAS: 2179-57-9; Diallyldisulfide

相似化合物

2179-58-0 110-81-6 2179-59-1

上下游产品

prop-2-ene-1-thiol allyl iodid allyl bromide S-allyl cysteineallicin diallyl sulphide -dithiin3-vinyl-4H-1,2-dithiin diallyl trisulfide

硫代乙酸烯丙酯置于盐酸,水,碘体系中,用 甲醇,水 用作溶剂,化学反应 0.75H,以82%的收率获得二烯丙基二硫
参考文献:一系列不饱和二硫化物对a549肺癌细胞抗癌活性的合成和初步评估†
标题:一系列不饱和二硫化物对a549肺癌细胞抗癌活性的合成和初步评估†
摘要:我们从有机醇开始,通过多步反应合成了一系列小的对称不饱和二硫化物,并进行了初步测试,以评估这些化合物对a549肺癌细胞生存力的影响.大蒜来源的天然化合物二烯丙基二硫化物,以其抗癌活性而闻名,在本研究中被用作主要化合物.我们合成了五个具有不同碳链长度和双键不同位置的dads类似物.两种类似物在体外表现出有希望的抗肿瘤活性,而烯丙基双键似乎不是主要驱动力.
Doi:10.1039/c8Md00503F

专利信息

专利号:US-6127489-A
优先权日:1996-05-20
标题:Silyl linker for solid phase organic synthesis of aryl-containing molecules
发明人：NEWLANDER KENNETH A; MOORE MICHAEL L
权利人:SMITHKLINE BEECHAM CORP
摘要:This invention relates to improved silyl linkers, methods for their preparation and their use in the solid phase synthesis of aromatic carbocycles, especially electron deficient aromatic carbocycles.

专利号:US-7429658-B2
优先权日:2003-09-11
标题 :Synthesis of protected pyrrolobenzodiazepines
发明人：HOWARD PHILIP; MASTERSON LUKE
权利人:SPIROGEN LTD
摘要:A method of synthesis of a N-10 protected PBD compound of formula (I): n nvia an intermediate of formula (II) or formula (V):

专利号:US-7557099-B2
优先权日:2004-03-01
标题 :Pyrrolobenzodiazepines as key intermediates in the synthesis of dimeric cytotoxic pyrrolobenzodiazepines
发明人：HOWARD PHILIP WILSON; KANG GYOUNG-DONG
权利人:SPIROGEN LTD
摘要:Compounds and a method of synthesis of compounds of formula (Ia) or (Ib): and salts, solvates, and chemically protected forms thereof, wherein the dotted lines indicate the optional presence of a double bond between C1 and C2 or C2 and C3; R 2 and R 3 are independently selected from —H, â• O, â• CH 2 , —CN, —R, OR, halo, â• CH—R, O—SO 2 —R, CO 2 R and COR; R 10 is a carbamate-based nitrogen protecting group; and R 11 is an oxygen protecting group.

专利号:US-7118627-B2
优先权日:2003-12-04
标 题 :Synthesis of colloidal PbS nanocrystals with size tunable NIR emission
发明人：HINES MARGARET A; SCHOLES GREGORY D
权利人:HINES MARGARET A; SCHOLES GREGORY D
摘要:The present invention discloses a method for synthesis of narrowly dipsersed colloidal PbS nanocrystals that offer size-tunable near-infrared emission. The stability and processibility of these near-infrared emitting quantum dots makes them ideal materials for device applications. The use of cost-effective and non-pyrophoric precursors as well as the success of larger scale reactions means the present invention provides a method for the industrial scale production of PbS nanocrystals.

专利号:US-11958751-B2
优先权日:2022-06-27
标 题:Method of synthesizing materials integrating supernatant recycle
发明人：HODGKINS ROBERT P; KOSEOGLU OMER REFA
权利人:SAUDI ARABIAN OIL CO
摘要:Methods are disclosed for synthesizing materials, including an initial synthesis in the presence of WS-ODSO (which can include a pH-modified WS-ODSO composition, in certain embodiments a neutralized WS-ODSO composition), and one or more subsequent syntheses using supernatant (“mother liquor†) from a previous synthesis of the same or different materials. The synthesized materials in the initial synthesis and in subsequent synthesis can be the same or different inorganic oxide materials including amorphous oxides, crystalline oxides or oxides of metals. The methods advantageously reduce the amount of utility water required for synthesizing a material and reduce the water waste, and reduce the DSO waste from a refinery and discharge into the environment. In certain embodiments the methods reduce the requirements to procure an alkaline reagent required for synthesizing materials. In certain embodiments, supernatant can be recycled over multiple synthesis batches of the same or different type of materia.

专利号:US-7781488-B2
优先权日:2002-06-10
标 题:Post-cleavage sulfur deprotection for convergent protein synthesis by chemical ligation
发明人：BOTTI PAOLO; VILLAIN MATTEO; MANGANIELLO SONIA; GAERTNER HUBERT
权利人:AMYLIN PHARMACEUTICALS INC
摘要:The present invention provides a method and compositions for synthesizing an oligopeptide or polypeptide by convergent assembly of a plurality of pairs of oligopeptides in chemical ligation reactions. An important aspect of the present invention is an oligopeptide having a C-terminal disulfide-protected carboxythioester group that can be deprotected to spontaneously generate a free C-terminal thioester moiety. This allows a single precursor to participate in a succession of chemical ligation reactions, thereby making the convergent synthesis approach possible. The present invention is useful in methods for chemical synthesis of oligopeptides, polypeptides and proteins, and improves the efficiency of native chemical ligation reactions, particularly where four or more peptide fragments are used to assemble an oligopeptide, polypeptide or protein product.