CAS: 212555-23-2; (2,4,6-Trimethoxyphenyl)Methanethiol

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CAS号61040-78-6 2,4,6-三甲氧基苯乙醇 | CAS号651305-76-9 (2,4,6-trimetho...

📜2,4,6-三甲氧基苯甲醛置于甲醇,Sodium Tetrahydroborate,对甲苯磺酸,硫脲体系中,用 乙腈 用作溶剂,化学反应 1.17H,反应生成2,4,6-三甲氧基苄硫醇
参考文献:新規な化合物,薬剤およびnk3受容体拮抗剤
标题:新規な化合物,薬剤およびnk3受容体拮抗剤
摘要:提供不影响生态系统的nk3受体拮抗体,抑制动物繁殖.化合物由式(i')表示.(r1为h,羟基等;R2为羟基,巯基等;R3为苯基或萘基).[选择图]无

专利信息

专利号:US-2025207163-A1
优先权日:2022-03-25
标 题:Methods and apparatus for synthesizing nucleic acids
发明人：HOPKINS PATRYCJA A; SHAHSAVARI SHAHIEN; BEGOYAN VAGARSHAK; NJUMA OLIVE J; DEBENHAM HOLLY S; EFCAVITCH J WILLIAM; ALBIZATI KIM F
权利人:MOLECULAR ASSEMBLIES INC
摘要:Methods for the synthesis of polynucleotides using polymerases nucleotide analogs with labile terminator groups that allow stepwise addition of nucleotides are described. These nucleotide analogs may have a modification on 3′, 2′, or 3′-2′-bridged hydroxyl groups or on nucleobase moieties and can be used in the synthesis of natural or modified polynucleotides suitable for use in biological systems. The labile terminator groups are removed under mild conditions or by enzymes. They are accepted as substrates by polymerases. The synthesis may be carried out on a surface.

专利号:US-11548909-B2
优先权日:2015-11-06
标 题 :Methods of using nucleotide analogues
发明人：Marma Mong Sano; OLEJNIK JERZY; KORBOUKH ILIA
权利人:ISOPLEXIS CORP
摘要:The present invention provides methods, compositions, mixtures and kits utilizing deoxynucleoside triphosphates comprising a 3′-O position capped by a group comprising methylenedisulfide as a cleavable protecting group and a detectable label reversibly connected to the nucleobase of said deoxynucleoside. Such compounds provide new possibilities for future sequencing technologies, including but not limited to Sequencing by Synthesis.

专利号:US-11821032-B2
优先权日:2018-01-24
标 题 :DNA sequencing reaction additive
发明人：ANDRUZZI LUISA; ADEDIRAN JIMMY; PELLETIER TIMOTHY; RICKER AUSTIN; DeLucia Angela; MCNALLY BEN; HEVRONI DONA; Marma Mong Sano; SHERIDAN JOHN ANDREW
权利人:ISOPLEXIS CORP
摘要:The present invention provides methods, compositions, mixtures and kits utilizing 5-Chloro-2-methyl-4-isothiazolin-3-one in sequencing reactions, and in particular, sequencing reactions where deoxynucleoside triphosphates comprising a 3′-O position capped by a disulfide-based 3′-terminator group are used. In one embodiment, the deoxynucleoside triphosphates comprise a 3′-O position capped by a group comprising methylenedisulfide as a cleavable protecting group and a detectable label reversibly connected to the nucleobase of said deoxynucleoside. In addition, thiol-containing compounds and scavengers of thio-containing compounds are described. Such compounds provide new possibilities for future sequencing technologies, including but not limited to Sequencing by Synthesis.

专利号:US-11421264-B2
优先权日:2015-11-06
标 题:Thiol-containing cleave reagents and oxidative wash
发明人：Marma Mong Sano; ANDRUZZI LUISA; MCNALLY BEN; DeLucia Angela; HEVRONI DONA; CARPENTER ELIZABETH; BESEV MAGNUS
权利人:ISOPLEXIS CORP
摘要:The present invention provides methods, compositions, mixtures and kits utilizing deoxynucleoside triphosphates comprising a 3′-O position capped by a group comprising methylenedisulfide as a cleavable protecting group and a detectable label reversibly connected to the nucleobase of said deoxynucleoside. In addition, thiol-containing compounds and scavengers of thio-containing compounds are described. Such compounds provide new possibilities for future sequencing technologies, including but not limited to Sequencing by Synthesis.