CAS: 200509-41-7; (2R)-(Tetrahydrofuran-2-yl)Methyl 2-(4-((6-Chloroquinoxalin-2-yl)Oxy)Phenoxy)Propanoate

该化合物是一种选择性的抗除草剂,主要用于控制宽叶麻作物中的草杂草;它属于丙氧基丙酰丙丙烯酸化学类,其功能是抑制对植物脂肪酸合成至关重要的酶乙酰-CoA carboxylase;这种除草剂的特点是其系统化行动,允许其被整个植物的叶片吸收和转移,有效地针对积极生长的杂草.Quizalof-p-tefuryl通常作为一种解决办法制定,以提高其应用效率和使用方便性.它对哺乳动物的毒性较低,在使用标签时一般认为安全.环境持久性是中度的,遵守准则以尽量减少对非目标物种和生态系统的潜在影响十分重要.

结构式图片

欧盟法规

统一分类与标签REACH注册ECHA物质食品接触材料-禁用CMR物质工作场所安全标识要求化妆品禁用物质清单C&L通报ECHA物质REACH预注册废弃物危险特性清单

上下游产品

Tetrahydrofurfuryl alcohol (R)-2-[4-[(6-chloro-2-quinoxalinyl)oxy]phenoxy]propanoic acid ethyl ester

合成工艺路线路线简述

    📜四氢糠醇,Quizalofop-P-Ethyl置于二正丁基氧化锡体系中,化学反应 8.0H,以98%的收率获得糖草酯 溶液
    参考文献:一种合成高质量喹禾糠酯的方法
    标题:一种合成高质量喹禾糠酯的方法
    摘要:本发明公开了一种合成高质量喹禾糠酯的方法,其包括:(R)‑2‑[4(6‑氯‑2‑喹恶啉氧基)苯氧基]丙酸乙酯和四氢糠醇在催化剂二丁基氧化锡作用下于90oc~180oc下进行反应.使用本发明的方法可以无需复杂后处理直接得到97%以上含量,光学有效体97%以上的高质量喹禾糠酯,反应收率达到97%以上.

    海关参考信息

    专利信息


    专利号:US-2021386068-A1
    优先权日:2018-11-07
    标题 :Compositions comprising pyridine carboxylate herbicides and very long chain fatty acid (vlcfa) synthesis inhibitor herbicides
    发明人:KISTER JEREMY; SATCHIVI NORBERT M
    权利人:CORTEVA AGRISCIENCE LLC
    摘要:Disclosed herein are compositions comprising (a) a pyridine carboxylate herbicide or an agriculturally acceptable N-oxide, salt, or ester thereof and (b) a VLCFA synthesis inhibitor herbicide. Also disclosed herein are methods of controlling undesirable vegetation, comprising applying to vegetation or an area adjacent the vegetation or applying in soil or water to control the emergence or growth of vegetation (a) a pyridine carboxylate herbicide or an agriculturally acceptable N-oxide, salt, or ester thereof, and (b) a VLCFA synthesis inhibitor herbicide.

    专利号:US-2021352899-A1
    优先权日:2018-11-07
    标题 :Compositions comprising pyridine carboxylate herbicides and fatty acid and lipid synthesis inhibitor herbicides
    发明人:KISTER JEREMY; SATCHIVI NORBERT M
    权利人:CORTEVA AGRISCIENCE LLC
    摘要:Disclosed herein are compositions comprising (a) a pyridine carboxylate herbicide or an agriculturally acceptable N-oxide, salt, or ester thereof and (b) a fatty acid and lipid synthesis inhibitor (FA/LSI) herbicide, an agriculturally acceptable salt or ester thereof, or mixtures thereof. Also disclosed herein are methods of controlling undesirable vegetation, comprising applying to vegetation or an area adjacent the vegetation or applying in soil or water to control the emergence or growth of vegetation (a) a pyridine carboxylate herbicide or an agriculturally acceptable N-oxide, salt, or ester thereof and (b) a fatty acid and lipid synthesis inhibitor (FA/LSI) herbicide, an agriculturally acceptable salt or ester thereof, or mixtures thereof.

    专利号:US-2010190794-A1
    优先权日:2007-06-12
    标 题:Herbicidally Active Composition
    发明人:HUPE EIKE; MOBERG WILLIAM KARL; REINHARD ROBERT; SIEVERNICH BERND; KIBLER ELMAR
    权利人:BASF SE
    摘要:The present invention relates to herbicidally active compositions comprising at least one piperazinedione compound of the formula I n n n n n n n n n n n n in which: n R x , R y are each hydrogen or together are a chemical bond; n R 1 is cyano or nitro; n R 2 is hydrogen, fluorine, chlorine, C 1 -C 2 -alkyl, ethenyl or C 1 -C 2 -alkoxy; n R 3 is fluorine or hydrogen; n R 4 is methyl; n R 5 is hydrogen, methyl or ethyl; n R 6 is hydrogen, methyl or ethyl; and n R 7 is hydrogen or halogen; n and at least one further active compound selected from the group consisting of n b1) lipid biosynthesis inhibitors; n b2) acetolactate synthase inhibitors (ALS inhibitors); n b3) photosynthesis inhibitors; n b4) protoporphyrinogen-IX oxidase inhibitors, n b5) bleacher herbicides; n b6) enolpyruvyl shikimate 3-phosphate synthase inhibitors (EPSP inhibitors); n b7) glutamine synthetase inhibitors; n b8) 7,8-dihydropteroate synthase inhibitors (DHP inhibitors); n b9) mitose inhibitors; n b10) inhibitors of the synthesis of very long chain fatty acids (VLCFA inhibitors); n b11) cellulose biosynthesis inhibitors; n b12) decoupler herbicides; n b13) auxin herbicides; n b14) auxin transport inhibitors; n b15) other herbicides, and n C) safeners.

    专利号:US-2011230343-A1
    优先权日:2008-10-24
    标题 :Method for the Manufacture of Microparticles Comprising an Effect Substance
    发明人:SCHROERS MICHAEL; DYLLICK-BRENZINGER RAINER; MERK MICHAEL; BARG HEIKO
    权利人:BASF SE
    摘要:A subject matter of the present invention is a process for the preparation of effect compound-comprising microparticles M comprising A) the formation of a crude suspension of microparticles A by means of enzymatic polyester synthesis in an inverse miniemulsion comprising enzyme, effect compound and polyester monomers; and B) the polymerization of wall monomers from the group consisting of ethylenically unsaturated monomers, polyisocyanates and polyepoxides in the crude suspension of microparticles A. Furthermore, the present invention relates to microparticles M which can be obtained by means of the process according to the invention and also to an agrochemical formulation comprising microparticles M. In addition, the present invention relates to the use of microparticles M prepared according to the invention as component in colorants, cosmetics, drugs, biocides, plant protection agents, fertilizers, additives for food or animal fodder, or auxiliaries for polymers, paper, textiles, leather, detergents or cleaners. Finally, the invention also relates to a method for combating undesirable plant growth, to a method for combating undesirable insect or acarid infestation on plants and/or for combating phytopathogenic fungi, and to seeds treated with the agrochemical formulation.

    专利号:US-2021163451-A1
    优先权日:2018-05-16
    标题:Methods and compositions for substituted 2,5-diketopiperazine analogs
    发明人:DING YOUSONG; JIANG GUANGDE
    权利人:UNIV FLORIDA
    摘要:Thaxtomins are phytotoxic secondary metabolites produced in plant pathogenic Streptomyces strains and have received considerable interests as bioherbicides. A cell-free, biocombinatorial approach was developed to produce a thaxtomin library for herbicide development. Combination of biosynthetic enzymes led to the production of 136 substituted 2,5-diketopiperazines, thaxtomin D, thaxtomin B and thaxtomin A analogs in a single pot. Furthermore, rational engineering of TxtA allowed the synthesis of azido-containing thaxtomin analog. Selected unnatural thaxtomins demonstrated improved herbicidal activities. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.

    专利号:EP-3650430-A1
    优先权日:2015-05-12
    标题 :Intermediates and processes for the synthesis of herbicides

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献


    1: European Food Safety Authority (EFSA); Brancato A, Brocca D, De Lentdecker C, Erdos Z, Ferreira L, Greco L, Jarrah S, Kardassi D, Leuschner R, Lythgo C, Medina P, Miron I, Molnar T, Nougadere A, Pedersen R, Reich H, Sacchi A, Santos M, Stanek A, Sturma J, Tarazona J, Theobald A, Vagenende B, Verani A, Villamar- Bouza L. Review of the existing maximum residue levels for quizalofop-P-ethyl, quizalofop-P-tefuryl and propaquizafop according to Article 12 of Regulation (EC) No 396/2005. EFSA J. 2017 Dec 12;15(12):e05050. doi: 10.2903/j.efsa.2017.5050.
    2: López-Ruiz R, Romero-González R, Martínez Vidal JL, Garrido Frenich A. Behavior of quizalofop-p and its commercial products in water by liquid chromatography coupled to high resolution mass spectrometry. Ecotoxicol Environ Saf. 2018 Aug 15;157:285-291. doi: 10.1016/j.ecoenv.2018.03.094. Epub 2018 Apr 5. 607-608:204-213. doi: 10.1016/j.scitotenv.2017.06.261. Epub 2017 Jul 27. 12(5):420. doi: 10.3390/insects12050420.
    5: Chawla S, Patel HK, Gor HN, Vaghela KM, Solanki PP, Shah PG. Evaluation of Matrix Effects in Multiresidue Analysis of Pesticide Residues in Vegetables and Spices by LC-MS/MS. J AOAC Int. 2017 May 1;100(3):616-623. doi: 10.5740/jaoacint.17-0048. Epub 2017 Mar 16. 23(1):113. Chinese.

    合成参考文献


    参考文献:10.1007/978-3-030-54719-6_6
    摘要:Anuradha, Singh J. Occurrence and Removal of Pesticides in Drinking Water. 2020 Dec 22. In: Sustainable Agriculture Reviews.
    参考文献:10.3103/s1068367423040110
    摘要:Pamirsky IE, Timkin PD, Timofeev EA, Kotelnikov DD, Alekseiko LN, Klimovich SV, Borodin EA, Golokhvast KS. A Study on the Molecular Mechanisms of Herbicide Binding with Target Proteins in Weeds Using In Silico Methods. Russ. Agricult. Sci. 2023 Aug;49(4):374–84. doi: 10.3103/s1068367423040110.
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