CAS: 1123-56-4; 2,6-Dimethylbenzaldehyde

该化合物是一种芳香藻,其特点是化学结构独特,其特点是2和6个位置上以两个甲基组取代苯环,1个位置是甲醛功能组(CHO),该化合物一般表现为无色的黄色液体,具有强酸,甜甜和花粉味,在香味工业中有用;其沸点相对较低,在有机溶剂中可溶解,但在水中仅略易溶;其存在导致其反应性,特别是在凝聚反应中和作为各种有机合成工艺中的潜在电极;此外,2,6-二甲基苯甲胺可氧化成相应的碳酸,并可以参与各种化学转化,包括核糖添加和芳香替代;其应用范围超出脆弱程度,包括药物和农业化学合成中的用途.

结构式图片

相似化合物

632-46-2 6575-13-9 62285-58-9

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上下游产品

CAS号576-22-7 2-溴间二甲苯 | CAS号68-12-2 N,N-二甲基甲酰胺 | CAS号6575-13-9 2,6-二甲基苯腈 | CAS号2039-90-9 2-乙烯基-1,3-二甲基苯 | CAS号608-28-6 1,3-二甲基-2-碘苯 | CAS号201230-82-2 carbon monoxide | CAS号124-38-9 二氧化碳 | CAS号62285-58-9 2,6-二甲基苯甲醇 | CAS号632-46-2 2,6-二甲基苯甲酸 | CAS号21900-37-8 2,6-二甲基苯甲酰氯 | CAS号54708-14-4 2,6-二甲基苯乙腈 | CAS号22004-65-5 α-(2,6-二甲基苯基)-2... | CAS号2039-90-9 2-乙烯基-1,3-二甲基苯 | CAS号19111-74-1 Benzonitrile,2,... | CAS号27843-11-4 2-(2,6-dimethyl... | CAS号6575-13-9 2,6-二甲基苯腈 | CAS号62285-58-9 2,6-二甲基苯甲醇 | CAS号5402-60-8 2,6-二甲基苄氯 | CAS号13935-97-2 2-(2,6-dimethyl... | CAS号2142-76-9 2',6'-二甲基苯乙酮

合成工艺路线路线简述

    (2,6-Dimethylphenyl)(Dimethylamino)Methoxide Magnesium Bromide置于盐酸体系中,用 水 用作溶剂,化学反应生成2,6-二甲基苯甲醛
    参考文献:Process For Preparing 2,6-Dialkylphenylacetic Acids
    标题:Process For Preparing 2,6-Dialkylphenylacetic Acids
    摘要:该发明涉及一种多阶段工艺,用于通过将2,6-二烷基溴苯与(1)镁,(2)甲酰胺,(3)酸,(4)氢化所得的苯甲醛,(5)激活所得的苄醇,(6)活化苄醇的氰化和(7)水解所得的腈来制备通式(i)的2,6-二烷基苯乙酸.

    海关参考信息

    专利信息


    专利号:US-8202985-B2
    优先权日:2005-10-31
    标 题:Monomer compositions for the synthesis of polynucleotides, methods of synthesis, and methods of deprotection
    发明人:DELLINGER DOUGLAS J; TIMAR ZOLTAN; SIERZCHALA AGNIESZKA; DELLINGER GERALDINO; CARUTHERS MARVIN H
    权利人:DELLINGER DOUGLAS J; TIMAR ZOLTAN; SIERZCHALA AGNIESZKA; DELLINGER GERALDINO; CARUTHERS MARVIN H; AGILENT TECHNOLOGIES INC; UNIV COLORADO
    摘要:Nucleotide monomers, polynucleotides, methods of making each, and methods of deprotecting each, are disclosed. An embodiment of the nucleotide monomer, among others, includes a nucleotide monomer having a heterobase protecting group selected from structures I through III as described herein. An embodiment of the polynucleotide, among others, includes a plurality of nucleotide moieties having a heterobase protecting group selected from one of structures I through III as described herein.

    专利号:US-7759471-B2
    优先权日:2005-10-31
    标题 :Monomer compositions for the synthesis of RNA, methods of synthesis, and methods of deprotection
    发明人:DELLINGER DOUGLAS J; TIMAR ZOLTAN; SIERZCHALA AGNIESZKA; DELLINGER GERALDINE; CARUTHERS MARVIN H
    权利人:AGILENT TECHNOLOGIES INC; UNIV COLORADO
    摘要:Nucleotide monomers, polynucleotides, methods of making each, methods of deprotecting each, and the like are disclosed herein.

    专利号:EP-0855388-B1
    优先权日:1993-11-23
    标 题 :Method for making intermediates useful in synthesis of retroviral protease inhibitors
    发明人:NG JOHN S; PRZYBYLA CLAIRE A; MUELLER RICHARD A; VAZQUEZ MICHAEL L; GETMAN DANIEL P; FRESKOS JOHN J; DECRESCENZO GARY A; BERTENSHAW DEBORAH E; HEINTZ ROBERT M; ZHANG SUHONG; LIU CHIN; LANEMAN SCOTT A
    权利人:SEARLE & CO
    摘要:A synthesis is described for intermediates which are readily amenable to the large scale preparation of hydroxyethylurea-based chiral HIV protease inhibitors. The method includes forming a cyanohydrin from a chiral alpha amino aldehyde.

    专利号:US-2007100138-A1
    优先权日:2005-10-31
    标题:Monomer compositions for the synthesis of polynucleotides, methods of synthesis, and methods of deprotection

    专利号:US-2007100136-A1
    优先权日:2005-10-31
    标题:Monomer compositions for the synthesis of RNA, methods of synthesis, and methods of deprotection

    专利号:EP-2001896-A2
    优先权日:2006-03-23
    标 题 :Monomer compositions for the synthesis of rna, methods of synthesis, and methods of deprotection
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    合成参考文献


    摘要:Molander, G. A.; Beaumard, F., Science of Synthesis Knowledge Updates, (2013) 3, 132.
    摘要:Kwiecień, H., Science of Synthesis Knowledge Updates, (2018) 3, 122.
    摘要:Clark, T. B.; Cho, H. Y., Science of Synthesis: Advances in Organoboron Chemistry towards Organic Synthesis, (2019) 1, 148.
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