CAS: 10544-72-6; Dinitrogen Tetroxide

结构式图片

物理性质

欧盟法规

统一分类与标签压力设备指令-第1组危险流体REACH注册ECHA物质工作场所安全标识要求ECHA物质C&L通报CoRAP评估清单REACH预注册废弃物危险特性清单

上下游产品

nitroacetic acid ethyl ester ethanol isopentyl nitrite MEDINA4-butanolide succinic acid piperonal 1,5-dimethyl-4-nitroso-2-phenyl-1,2-dihydro-pyrazol-3-one

合成工艺路线路线简述

  • 合成目标产物 Nitrogen Tetroxide 主要起始原料 Hydrogen Fluoride And Silicon
  • (文献来源)合成步骤主要原料 Hydrogen Fluoride 和 Silicon
📜硝酸 反应生成二氧化氮
参考文献:Arutyunyan,V. A.;Zavidkova,G. N.;Romanov,S. A.;Miniovich,V. M.,Teor. Osnovy Pr-Ba Azot. Udobr.,M.,(1988) S. 29-32
标题:Arutyunyan,V. A.;Zavidkova,G. N.;Romanov,S. A.;Miniovich,V. M.,Teor. Osnovy Pr-Ba Azot. Udobr.,M.,(1988) S. 29-32

专利信息


专利号:US-2010173100-A1
优先权日:2006-01-16
标题 :Method for the synthesis of product molecules
发明人:WEISS HORST; GERBER GUSTAV; NUERNBERGER PATRICK HENNING; WOLPERT DANIEL STEPHAN
权利人:BASF AG
摘要:The invention relates to a method for the synthesis of product molecules, wherein ultrashort laser pulses shaped with the aid of a pulse shaper are generated and a gas which contains educt molecules is fed onto a surface, on which the educt molecules are at least partially adsorbed, the shaped ultrashort laser pulses being directed onto the surface in order to control a reaction process for synthesis of the product molecules from educts adsorbed on the surface.

专利号:US-10730904-B2
优先权日:2012-11-14
标 题:Method for liquid-phase synthesis of nucleic acid
发明人:NONOGAWA MITSURU; NAGATA TOSHIAKI; SAITO HIDEKI; YASUMA TSUNEO
权利人:TAKEDA PHARMACEUTICALS CO
摘要:In this method, an oligonucleotide represented by formula (II) [wherein Y 1 , Q, Base, r and r′ are each as defined in claim 1 ] is prepared by using, as a synthesis unit, a novel nucleoside monomer compound represented by formula (I) [wherein X, R 1 , Y, Base, Z, Ar, R 2 , R 3 and n are each as defined in claim 1 ]. The novel nucleoside monomer compound is a nucleoside, the base moiety of which is substituted with an aromatic-hydrocarbon-ring-carbonyl or -thiocarbonyl group having at least one hydrophobic group. The method can dispense with column-chromatographic purification in every reaction, and enables base elongation not only in the 3′-direction but also in the 5′-direction, thus attaining efficient liquid-phase mass synthesis of an oligonucleotide.

专利号:WO-9714703-A1
优先权日:1995-10-16
标 题:Synthesis of polymerisable phosphodiesters
发明人:DRIVER MICHAEL JOHN; RUSSEL JEREMY COLIN; BROWNE JUDITH ELIZABETH; SAMMES PETER G
权利人:BIOCOMPATIBLES LTD; DRIVER MICHAEL JOHN; RUSSEL JEREMY COLIN; BROWNE JUDITH ELIZABETH; SAMMES PETER G
摘要:A mono- or di-functional phosphoramidite phosphitylating agent is used to phosphitylate an ethylenically unsaturated alcohol. The product may be oxidised to form the corresponding phosphate ester which may be reacted in further steps to form phosphoryl choline derivatives. The process is of value in the synthesis of 2-(Methacryloyloxyethyl)-2'-(trimethylammoniumethyl)phosphate, inner salt. It has the advantage over prior art processes in that the starting materials and intermediates are more stable and consequently easier to handle.

专利号:WO-9847910-A1
优先权日:1997-04-21
标题:Method for solution phase synthesis of oligonucleotides
发明人:PIEKEN WOLFGANG; MCGEE DANNY; SETTLE ALECIA; ZHAI YANSHENG; HUANG JIANPING; HILL KEN; SMITH RANDALL S
权利人:NEXSTAR PHARMACEUTICALS INC; PIEKEN WOLFGANG; MCGEE DANNY; SETTLE ALECIA; ZHAI YANSHENG; HUANG JIANPING; HILL KEN; SMITH RANDALL S
摘要:This invention discloses an improved method for the sequential solution phase synthesis of oligonucleotides. The method lends itself to automation and is ideally suited for large scale manufacture oligonucleotides with high efficiency.

专利号:EP-0836612-B1
优先权日:1995-05-23
标 题 :Novel synthons for stereoselective oligonucleotide synthesis
发明人:IYER RADHAKRISHNAN P; DEVLIN THERESA; HABUS IVAN; YU DONG; AGRAWAL SUDHIR
权利人:HYBRIDON INC
摘要:The invention provides new reagents and processes for synthesizing oligonucleotides, including stereoselective oligonucleotide synthesis. In a first aspect, the invention provides novel monomer synthons for the synthesis of oligonucleotides. Monomer synthons according to this aspect of the invention are useful in the synthesis of oligonucleotides and can be used in place of the well known beta-cyanoethyl phosphoramidite monomer synthon in the phosphoramidite synthesis procedure. Certain monomer synthons according to this aspect of the invention are useful in this procedure for producing oligonucleotides having defined stereochemistry. In a second aspect, the invention provides processes for synthesizing monomer synthons according to the invention, including diastereomerically enriched or purified monomer synthons. In the processes according to this aspect of the invention, the chemical reactions are stereoretentive so that the products of each reaction retain the same stereoconfiguration as their precursor reagent. In a third aspect, the invention provides processes for synthesizing oligonucleotides using the well known phosphoramidite approach. In the processes according to this aspect of the invention, any of the monomer synthons according to the invention is used in place of the conventional beta-cyanoethyl phosphoramidite.

专利号:WO-2025037082-A1
优先权日:2023-08-11
标题:Improved flow synthesis
发明人:MCWHIR NAIL; KENNEDY STUART; JONES CHRISTOPHER; DIDSBURY MATTHEW PAUL; JUBB DANIEL; THOMAS SIMON DAVID; MURRAY IAN EWART PATTERSON
权利人:BAE SYSTEMS PLC
摘要:The invention relates to a method for the flow synthesis manufacture of energetic materials with a two stage-temperature reactor. There is provided a flow reactor for the synthesis of energetic materials, comprising; i. a first input flow reagent, and a second input flow reagent ii. a flow reactor, comprising at least two temperature zones within the reactor. (Formula (I))

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合成参考文献


摘要:Aggarwal, P.; Bebbington, M. W. P., Science of Synthesis Knowledge Updates, (2012) 2, 484.
摘要:Riva, R.; Banfi, L.; Basso, A., Science of Synthesis: Multicomponent Reactions, (2013) 1, 337.
摘要:Lumb, J.-P.; Esguerra, K. V. N., Science of Synthesis: Catalytic Oxidation in Organic Synthesis, (2017) 1, 606.
摘要:SRI. 1997 Directory of Chemical Producers -United States of America. Menlo Park, CA: SRI International 1997., p. 772807
摘要:
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