CAS: 98-73-7; 4-(Tert-Butyl)Benzoic Acid

上下游产品

tert-butylbenzene di-tert-butyl peroxide 1-((benzyloxy)methyl)-4-(tert-butyl)benzene p-tert.-Butyl-cumol p-t-butyl benzoic acid anhydride ethyl 4-tert-butylbenzoate tert-butyl-benzoic acid-(2-dibutylamino-ethyl ester)4-tert-butyl-benzoic acid-(2-dibutylamino-ethyl ester) 4-t-Butylbenzoesaeure-diethylaminoethylester

P-Tert.-Butyl-Cumol置于cobalt(II) Acetate,Manganese Triacetate 二叔丁基过氧化物,氧气,丁酸体系中,150.0 °C,101.32 Kpa 条件下,反应生成 对叔丁基苯甲酸
参考文献:Van Helden,R. Et Al.,Recueil Des Travaux Chimiques Des Pays-Bas,1961,Vol. 80,P. 1237-1253
标题:Van Helden,R. Et Al.,Recueil Des Travaux Chimiques Des Pays-Bas,1961,Vol. 80,P. 1237-1253

专利信息

专利号:US-8293930-B1
优先权日:2004-06-25
标题 :One pot synthesis of taxane derivatives and their conversion to paclitaxel and docetaxel
发明人：NAIDU RAGINA
权利人:NAIDU RAGINA; CHATHAM BIOTEC LTD
摘要:A process is provided for the semi-synthesis of taxane intermediates useful in the preparation of paclitaxel and docetaxel, in particular, the semi-synthesis of protected taxane intermediate in a one pot reaction of protecting the C-7 and C-10 positions and attaching a side chain at the C-13 position and subsequently deprotecting the group to form paclitaxel or docetaxel, and taxane intermediates.

专利号:US-7893283-B2
优先权日:2004-06-04
标题:Semi-synthesis of taxane intermediates and their conversion to paclitaxel and docetaxel
发明人：NAIDU RAGINA
权利人:CHATHAM BIOTEC LTD
摘要:A process is provided for the semi-synthesis of taxane intermediates useful in the preparation of paclitaxel and docetaxel, in particular, the semi-synthesis of protected taxane intermediates.

专利号:WO-2008032104-A1
优先权日:2006-09-15
标题:One pot synthesis of taxane derivatives and their conversion to paclitaxel and docetaxel
发明人：WALKER ROSS THOMSON; NAIDU RAGINA
权利人:CHATHAM BIOTEC LTD; WALKER ROSS THOMSON; NAIDU RAGINA
摘要:A process is provided for the semi-synthesis of taxane intermediates useful in the preparation of paclitaxel and docetaxel, in particular, the semi-synthesis of protected taxane intermediate in a one pot reaction, of protecting the C-10 and attaching a side chain at C-13 position and subsequently deprotecting the group to form paclitaxel or docetaxel, and intermediates used therein.

专利号:US-7202370-B2
优先权日:2003-10-27
标 题 :Semi-synthesis of taxane intermediates from 9-dihydro-13-acetylbaccatin III
发明人：NAIDU RAGINA
权利人:CONOR MEDSYSTEMS INC
摘要:A method is provided for the semi-synthesis of taxane intermediates useful in the preparation of paclitaxel and docetaxel from 9-dihydro-13-acetylbaccatin III. The preparation of a suitably protected baccatin III backbone from 9-dihydro-13-acetylbaccatin III, and the insertion of the phenylisoserine side chain onto the protected baccatin III from 9-dihydro-13-acetylbaccatin III to form the taxane derivatives, paclitaxel and docetaxel is disclosed.

专利号:US-2005192445-A1
优先权日:2004-03-01
标题:Semi-synthesis of taxane intermediates and aziridine analogues and their conversion to paclitaxel and docetaxel
发明人：NAIDU RAGINA
权利人:PHYTOGEN LIFE SCIENCES INC
摘要:A process is provided for the semi-synthesis of taxane intermediates and aziridine analogues of cephalomannne and baccatin III intermediates, and the conversion of such intermediates and analogues to paclitaxel and docetaxel.

专利号:US-7585986-B2
优先权日:2004-02-24
标题 :Semi-synthesis of taxane intermediates and aziridine analogues and their conversion to paclitaxel and docetaxel
发明人：NAIDU RAGINA
权利人:CHATHAM BIOTEC LTD
摘要:A process is provided for the semi-synthesis of taxane intermediates and aziridine analogues of cephalomannine and baccatin III intermediates, and the conversion of such intermediates and analogues to paclitaxel and docetaxel.