CAS: 695-56-7; 1,4-Dioxaspiro[4.4]Non-6-Ene

相似化合物

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上下游产品

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📜环戊酮置于溴体系中,用 乙二醇 作为反应溶剂,化学反应生成 2-环戊烯-1-酮缩乙醛
参考文献:N-Amino Bicyclic Compounds
标题:N-Amino Bicyclic Compounds
摘要:N-氨基六氢环戊咪唑-2(1H)-酮衍生物,用于治疗或预防由增加眼压引起的血栓栓塞性疾病和眼部疾病.

专利信息

专利号:US-7612106-B2
优先权日:2004-12-23
标题 :Fused pyrazole derivatives and methods of treatment of metabolic-related disorders thereof
发明人：BOATMAN P DOUGLAS; SCHRADER THOMAS O; SEMPLE GRAEME; SKINNER PHILIP J; JUNG JAE-KYU
权利人:ARENA PHARM INC
摘要:The present invention relates to certain fused pyrazole derivatives of Formula (Ia), and pharmaceutically acceptable salts thereof, which exhibit useful pharmacological properties, for example, as agonists for the RUP25 receptor. n nAlso provided by the present invention are pharmaceutical compositions containing compounds of the invention, and methods of using the compounds and compositions of the invention in the treatment of metabolic-related disorders, including dyslipidemia, atherosclerosis, coronary heart disease, insulin resistance, type 2 diabetes, Syndrome-X and the like. In addition, the present invention also provides for the use of the compounds of the invention in combination with other active agents such as those belonging to the class of α-glucosidase inhibitors, aldose reductase inhibitors, biguanides, HMG-CoA reductase inhibitors, squalene synthesis inhibitors, fibrates, LDL catabolism enhancers, angiotensin converting enzyme (ACE) inhibitors, insulin secretion enhancers, DP receptor antagonists, and the like.