CAS: 69221-14-3; (1S,2R,4S,5R)-1-Benzyl-2-(Hydroxy(Quinolin-4-yl)Methyl)-5-Vinylquinuclidin-1-Ium Chloride

相似化合物

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上下游产品

CAS号100-44-7 氯化苄 | CAS号118-10-5 辛可宁

📜氯化苄,辛可宁 以 乙醇,氯仿,N,N-二甲基甲酰胺 作为反应溶剂,化学反应 10.0H,以95%的收率获得产物n-苄基氯化辛可宁
参考文献:完美的绿色有机催化:季铵盐基引发醛的氰基硅烷化反应
标题:完美的绿色有机催化:季铵盐基引发醛的氰基硅烷化反应
摘要:发现季铵碱,例如(ch 3)4 Noh水溶液,是醛氰基硅烷化的一种非常有效的催化剂.在无溶剂条件下,三甲基甲硅烷基氰化物(tmscn)与等效醛的加成反应可以以高达3000000 H-1的周转频率(tof)顺利进行,并且收率接近100%.这些有机催化剂还可以耐受各种醛,包括芳族,脂族和α,β-不饱和醛.此过程完全符合绿色化学的特征:不会浪费副产物和未转化的反应物,无溶剂,催化活性出色,并且不需要分离.
DOI:10.1002/cjoc.201200598

专利信息

专利号:US-5554753-A
优先权日:1993-08-25
标 题:Catalytic enantioselective synthesis of α-amino acid derivatives by phase-transfer catalysis
发明人：O'DONNELL MARTIN J; WU SHENGDE; ESIKOVA IRENA; MI AIQIAO
权利人:INDIANA UNIVERSITY FOUNDATION
摘要:Described are improved processes for the enantioselective synthesis of α-amino acids which involve combinations of solvents, highly-mixed and low-temperature reaction conditions, and novel catalysts. Also described are novel catalysts and precursors to α-amino acid derivatives.

专利号:US-2024025839-A1
优先权日:2020-11-11
标 题 :Method of synthesis
发明人：KITCHING MATTHEW OLIVER; WALSH MARK PATRICK
权利人:UNIV DURHAM
摘要:The present invention provides a method of making an enantiomerically enriched tertiary or quaternary ammonium salt, and the use of a non-racemic chiral compound in the synthesis of an enantiomerically enriched tertiary or quaternary ammonium salt. The control of nitrogen-based chirality, achieved via the method of the invention, is useful where a specific tertiary or quaternary ammonium enantiomer is preferred over the other enantiomer, for example where a specific tertiary or quaternary ammonium enantiomer is more effective than the other enantiomer in treating a specific medical condition.

专利号:WO-9506029-A1
优先权日:1993-08-25
标 题:Enantioselective synthesis of alpha - alkylated amino acid derivatives by phase - transfer catalysis

专利号:CZ-278815-B6
优先权日:1990-01-22
标题 :Process for stereo selective synthesis of alkylated oxindole derivatives

专利号:WO-2022101627-A1
优先权日:2020-11-11
标题:Method of synthesis

专利号:EP-4244202-A1
优先权日:2020-11-11
标 题:Method of synthesis