CAS: 5734-66-7; 2-Amino-6-Ethylpyrimidin-4-Ol

该化合物是属于火烈因家族的有机化合物,其特点是六人组成的芳香环,含有1号阵地和3号阵地的两个氮原子. 该化合物的特征是2号阵地的氨基(-NH2)组和6号位置的乙基(-C2H5)组,有助于其独特的化学特性.该化合物一般是室温固态,由于存在氨氨基系,可能会在极地溶剂中表现出中等溶性.该化合物可参与各种化学反应,包括核生殖器替代和凝聚反应,使其对药用化学和合成药物感兴趣.其衍生物可能具有生物活动,在研制治疗剂时可作为中间体.应参考安全数据,以便处理和使用,与任何化学物质一样,确保采取适当的预防措施.

结构式图片

相似化合物

3977-29-5 19810-58-3 133062-09-6

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CAS号50-01-1 盐酸胍 | CAS号4949-44-4 丙酰基乙酸乙酯 | CAS号30414-53-0 丙酰乙酸甲酯 | CAS号64-17-5 乙醇 | CAS号593-85-1 碳酸胍 | CAS号5734-67-8 2-氨基-4-氯-6-乙基嘧啶 | CAS号58-14-0 乙胺嘧啶 | CAS号15043-03-5 6-乙基嘧啶-2,4(1H,3H)-二酮 | CAS号58331-07-0 2-amino-5-bromo... | CAS号514854-12-7 2,4-二氨基-6-乙基嘧啶 | CAS号514854-13-8 6-乙基-5-碘嘧啶-2,4-二胺 | CAS号514854-15-0 2-Pyrimidinamin...

合成工艺路线路线简述

  • 合成目标产物 4(1H)-Pyrimidinone, 2-Amino-6-Ethyl- (9CI) 主要起始原料 Guanidine Hydrochloride And Ethyl Propionylacetate
  • (文献来源)合成步骤主要原料 Guanidine Hydrochloride 和 Ethyl Propionylacetate
📜碳酸胍,丙酰乙酸乙酯 以 乙醇 作为反应溶剂,化学反应 5.0H,以34%的收率获得产物2-氨基-4-羟基-6-乙基嘧啶
参考文献:从面向多样性的合成中鉴定抗 Mrsa 二氢叶酸还原酶抑制剂.
标题:从面向多样性的合成中鉴定抗 Mrsa 二氢叶酸还原酶抑制剂.
摘要:筛选以多样性为导向的合成文库,然后进行结构-活性关系研究,从而发现了一种抗 Mrsa 试剂,该试剂可作为金黄色葡萄球菌二氢叶酸还原酶的抑制剂.
DOI:10.1039/b812901K

海关参考信息

专利信息


专利号:US-7329767-B2
优先权日:2003-10-03
标 题:Conjugated dienamides, methods of production thereof, compositions containing same and uses thereof
发明人:DEWIS MARK L; JOHN THUMPLASSERIL V; ECKERT MARKUS A; COLSTEE JAN HERMAN; DA COSTA NEIL C; PEI TAO
权利人:INT FLAVORS & FRAGRANCES INC
摘要:Described are mixtures of at least four of the alkadienamides defined according to the structure: n nwherein R represents C 1 -C 2 n-alkyl; R 1 is 2-methyl-1-propyl and R 2 is hydrogen, or R 1 and R 2 taken together is a moiety having the formulan n nwherein n is 4 or 5, or compositions containing substantial concentrations of such mixtures, prepared according to novel processes: (a) extraction of a ground substantially dried fruit of one of the Piper species, Piper longum Linn or Piper peepuloides ; (b) natural product-forming synthesis; or (c) synthetic product-forming synthesis. Also described are uses of the thus-formed products for augmenting, enhancing or imparting an aroma, taste, chemesthetic effect and/or antibacterial effect in or to a consumable material and/or in the oral cavity and/or on the mammalian epidermis.

专利号:US-8007841-B2
优先权日:2003-10-03
标 题 :Conjugated dienamides, methods of production thereof, compositions containing same and uses thereof
发明人:JOHN THUMPLASSERIL V; ECKERT MARKUS A; DEWIS MARK L; COLSTEE JAN HERMAN; DA COSTA NEIL C
权利人:INT FLAVORS & FRAGRANCES INC
摘要:Described are mixtures of at least four of the alkadienamides defined according to the structure: n nwherein R represents C 1 -C 2 n-alkyl; R 1 is 2-methyl-1-propyl and R 2 is hydrogen, or R 1 and R 2 taken together is a moiety having the formula —(CH 2 ) n —, wherein n is 4 or 5, or compositions containing substantial concentrations of such mixtures, prepared according to novel processes: (a) extraction of a ground substantially dried fruit of one of the Piper species, Piper longum Linn or Piper peepuloides ; (b) natural product-forming synthesis; or (c) synthetic product-forming synthesis. Also described are uses of the thus-formed products for augmenting, enhancing or imparting an aroma, taste, chemesthetic effect and/or antibacterial effect in or to a consumable material and/or in the oral cavity and/or on the mammalian epidermis.

专利号:US-11137242-B2
优先权日:2016-06-01
标 题:Conductive fiber comprising metal nanobelt and carbon nanomaterial composite, method for producing conductive fiber, fibrous strain sensor, and method for producing fibrous strain sensor
发明人:HAN JOONG TARK; LEE GEON WOONG; SEO SEON HEE; JANG JEONG IN; JEONG SEUNG YOL; JEONG HEE JIN
权利人:KERI KOREA ELECTROTECHNOLOGY RES INST
摘要:A conductive fiber including a metal-nanobelt-carbon-nanomaterial composite. A manufacturing method thereof includes preparing a composite including a carbon nanomaterial and metal nanobelts and manufacturing a conductive fiber by mixing the composite with a polymer. A fibrous strain sensor and a manufacturing method thereof are also provided. Thereby, a conductive fiber including a metal-nanobelt-carbon-nanomaterial composite, which is able to increase conductivity of the conductive fiber through synthesis of metal nanobelts enabling area contact and to exhibit good contact between the carbon nanomaterial and the metal nanobelts due to formation of the metal nanobelts on the surface of the carbon nanomaterial and superior dispersion uniformity, and a fibrous strain sensor including the conductive fiber can be obtained. The conductive fiber can be effectively applied to a strain sensor based on a principle by which resistance drastically increases with an increase in a distance between metal nanobelts aligned in a fiber direction upon tensile strain of metal nanobelts enabling area contact.

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合成参考文献

参考DOI号:10.1039/c4ra00249k
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