CAS: 5438-19-7; 4-Propoxybenzoic Acid

该化合物是一种芳香的碳盒酸,其特征是附于苯并硫酸结构的副位置的丙氧类,该化合物一般是白色的,在白色的固体中是白色的,在有机溶剂中可以溶解,而在水中的溶解性有限.该化合物含有一种致酸性,允许其参与各种化学反应,如洗涤和恐吓.丙氧基的出现会强化其疏水特性,影响其在生物和化学系统中的行为.4-丙基苯并经常用于合成药物,农用化学品和有机合成的中间体.其衍生物可能展示出有趣的生物活动,使其成为医学化学研究的课题.安全数据表明,与许多有机酸一样,处理该物质时应当小心避免皮肤和眼刺激.

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CAS号106-94-5 溴代丙烷 | CAS号99-76-3 尼泊金甲酯 | CAS号100256-94-8 ethyl 4-propoxy... | CAS号27914-60-9 4-(烯丙氧基)苯甲酸 | CAS号99-96-7 4-羟基苯甲酸 | CAS号120-47-8 尼泊金乙酯 | CAS号115478-59-6 METHYL 4-N-PROP... | CAS号16782-08-4 四羟基苯甲酸一钾 | CAS号622-85-5 丙氧基苯 | CAS号463-72-9 N-甲氨基甲酰氯 | CAS号64328-60-5 4-丙氧基苯甲酸肼 | CAS号115478-59-6 METHYL 4-N-PROP... | CAS号853055-31-9 6-oxo-6-[4-(4-p... | CAS号56800-28-3 (4-formylphenyl... | CAS号40782-58-9 4-丙氧基苯甲酰氯

合成工艺路线路线简述

    过氧化氢酶置于乙醇,Potassium Carbonate,Sodium Hydroxide体系中,用 N,N-二甲基甲酰胺 作为反应溶剂,化学反应生成 4-丙氧基苯甲酸
    参考文献:Synthesis And Study Of Vitrescent Materials Based On The Alkoxybenzoic Acids Derivatives And Triethanolamine
    标题:Synthesis And Study Of Vitrescent Materials Based On The Alkoxybenzoic Acids Derivatives And Triethanolamine
    摘要:Fifteen New Branched Triethanolamine Esters Of The Benzoic Acid Derivatives Were Designed And The Mesomorphism Typical Of Discotic Mesogens Was Forecast For Them. In Eight Of The Obtained Compounds A Manifestation Of Liquid Crystal Properties Was Predicted,For Four Derivatives Equiprobable Prognosis Was Given,And Only Three Compounds Were Predicted Not To Form A Mesophase. The Obtained Esters Were Characterized By Elemental Analysis,NMR And Ir Spectroscopy,Gas Chromatography-Mass Spectrometry. The Main Thermal Characteristics That Allow Accounting For Their Phase Behavior Were Determined.
    DOI:10.1134/s1070363213040075

    海关参考信息

    专利信息


    专利号:US-9175357-B2
    优先权日:2011-02-04
    标 题:Fragment ligated inhibitors selective for the polo box domain of PLK1
    发明人:MCINNES CAMPBELL; FARAG DOAA BOSHRA
    权利人:MCINNES CAMPBELL; FARAG DOAA BOSHRA; UNIV SOUTH CAROLINA
    摘要:Methods for developing non-peptidic inhibitors that target the polo-box domain of PLK1 proteins are described. Methods include developing structure activity relationships for peptidic inhibitors followed by development of non-peptide fragment alternatives for portions of the peptide inhibitors. The non-peptide fragment can provide similar structure activity relationship as the replaced peptide. Fragment alternatives to key binding determinants are identified in an iterative computational and synthetic process facilitated through understanding of the peptide structure-activity relationships. The approach is informed by peptide structure-activity data obtained through synthesis and testing of truncated and mutated analogs of known PBD binding motifs.

    专利号:US-9217012-B2
    优先权日:2009-04-08
    标题 :Inhibitors of protein tyrosine phosphatases
    发明人:ZHANG ZHONG-YIN; ZHANG SHENG
    权利人:ZHANG ZHONG-YIN; ZHANG SHENG; UNIV INDIANA RES & TECH CORP
    摘要:Disclosed herein are compounds that selectively inhibit members of the PTP family of enzymes. Synthesized compounds demonstrated selective inhibition of TC-PTP. Also provided are methods of using the compounds and formulations containing the compounds. Also described is a fluorescence-tagged combinatorial library synthesis and screening method. And methods of using these compounds to effect enzyme activity both in cells and in vitro as well as method of using these compounds to treat diseases in human and animals.

    专利号:US-2008176857-A1
    优先权日:2005-03-25
    标题 :4-Piperazinnylthieno[2,3-d]Pyrimidine Compounds as Platelet Aggregation Inhibitors
    发明人:ENNIS MICHAEL DALTON; KORTUM STEVEN WADE; TENBRINK RUTH ELIZABETH
    权利人:ENNIS MICHAEL DALTON; KORTUM STEVEN WADE; TENBRINK RUTH ELIZABETH
    摘要:Compounds and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula I: n n n n n n n n n n wherein A 1 , A 2 , A 3 , A 4 , A 5 , A 6 , A 7 , A 8 , X 4 , X 6 , R 2 , R 4 , R 5 , and R 6 are as defined in the detailed description of the invention. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.

    专利号:CN-1923793-A
    优先权日:2006-10-09
    标 题 :Synthesis method of aryl phenyl ester like compound

    专利号:EP-0260415-B1
    优先权日:1986-08-01
    标题:Synthesis and application of high molecular weight polyanhydrides
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    合成参考文献


    摘要:Vashchenko, B. V.; Grygorenko, O. O., Science of Synthesis Knowledge Updates, (2021) 3, 410.
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