CAS: 451-80-9; 1-Ethoxy-2-Fluorobenzene

该化合物是一种含分子式C8H9FO的氟芳烃醚,其特点是苯环上存在一个含乙氧化合物和氟原子,具有独特的反应性和稳定性;它是有机合成的多用途中间体,特别是在开发药品,农用化学品和特殊材料方面;氟代用品增强了其电子提取特性,使其对交叉相交反应和其他变异具有价值;其明确界定的结构和高纯度确保了研究和工业应用的一贯性;该化合物通常在标准实验室条件下处理,并注意符合其有机溶剂特性的适当安全协议.

结构式图片

欧盟法规

ECHA物质C&L通报

上下游产品

CAS号367-12-4 2-氟苯酚 | CAS号75-03-6 碘乙烷 | CAS号74-96-4 溴乙烷 | CAS号103-73-1 苯乙醚 | CAS号94-70-2 邻氨基苯乙醚 | CAS号367-12-4 2-氟苯酚 | CAS号452-00-6 4-乙氧基-3-氟苯甲醛 | CAS号2265-90-9 2-氟-4,6-二硝基苯酚

合成工艺路线路线简述

    📜Alkaline Earth Salt Of/the/ Methylsulfuric Acid 反应生成 2-氟代苯乙醚
    参考文献:Schiemann,Zeitschrift Fur Physikalische Chemie (Leipzig),1931,Vol. 156,P. 397,398
    标题:Schiemann,Zeitschrift Fur Physikalische Chemie (Leipzig),1931,Vol. 156,P. 397,398

    海关参考信息

    专利信息


    专利号:US-12336981-B2
    优先权日:2010-09-03
    标题 :Compounds and compositions for the inhibition of NAMPT
    发明人:BAIR KENNETH W; BAUMEISTER TIMM R; BUCKMELTER ALEXANDRE J; CLODFELTER KARL H; DRAGOVICH Peter; GOSSELIN FRANCIS; HAN BINGSONG; LIN JIAN; REYNOLDS DOMINIC J; ROTH BRUCE; SMITH CHASE C; WANG ZHONGGUO; YUEN PO-WAI; ZHENG XIAOZHANG
    权利人:VALO HEALTH INC; GENENTECH INC
    摘要:The present invention relates to compounds and compositions for the inhibition of NAMPT, their synthesis, applications, and antidotes. An illustrative compound of the invention is shown below:

    专利号:US-11279687-B2
    优先权日:2010-09-03
    标题:Compounds and compositions for the inhibition of NAMPT
    发明人:BAIR KENNETH W; BAUMEISTER TIMM R; BUCKMELTER ALEXANDRE J; CLODFELTER KARL H; HAN BINGSONG; LIN JIAN; REYNOLDS DOMINIC J; SMITH CHASE C; WANG ZHONGGUO; ZHENG XIAOZHANG; YUEN PO-WAI
    权利人:VALO HEALTH INC; GENENTECH INC
    摘要:The present invention relates to compounds and compositions for the inhibition of NAMPT, their synthesis, applications and antidotes. An embodiment of the invention is the provision of a compound of Formula IIIA.

    专利号:US-9676721-B2
    优先权日:2010-09-03
    标题 :Compounds and compositions for the inhibition of NAMPT
    发明人:BAIR KENNETH W; BUCKMELTER ALEXANDRE J; HAN BINGSONG; LIN JIAN; REYNOLDS DOMINIC J; SMITH CHASE C; WANG ZHONGGUO; ZHENG XIAOZHANG
    权利人:BAIR KENNETH W; BUCKMELTER ALEXANDRE J; HAN BINGSONG; LIN JIAN; REYNOLDS DOMINIC J; SMITH CHASE C; WANG ZHONGGUO; ZHENG XIAOZHANG; FORMA TM LLC
    摘要:The present invention relates to compounds and compositions for the inhibition of NAMPT, their synthesis, applications and antidotes. An illustrative compound of the invention is shown below.

    专利号:US-9555039-B2
    优先权日:2011-05-09
    标题:Piperidine derivatives and compositions for the inhibition of nicotinamide phosphoribosyltransferase (NAMPT)
    发明人:BAIR KENNETH W; BAUMEISTER TIMM R; BUCKMELTER ALEXANDRE J; CLODFELTER KARL H; HAN BINGSONG; KUNTZ JUDITH D; LIN JIAN; REYNOLDS DOMINIC J; SMITH CHASE C; WANG ZHONGGUO; ZHENG XIAOZHANG
    权利人:BAIR KENNETH W; BAUMEISTER TIMM R; BUCKMELTER ALEXANDRE J; CLODFELTER KARL H; HAN BINGSONG; KUNTZ JUDITH D; LIN JIAN; REYNOLDS DOMINIC J; SMITH CHASE C; WANG ZHONGGUO; ZHENG XIAOZHANG; FORMA TM LLC
    摘要:The present invention relates to compounds and compositions for the inhibition of NAMPT, their synthesis, applications and antidotes. An illustrative compound of the invention is shown below: Formula (I)

    专利号:US-9169209-B2
    优先权日:2011-05-04
    标题:Compounds and compositions for the inhibition of NAMPT
    发明人:BAIR KENNETH W; BAUMEISTER TIMM; BUCKMELTER ALEXANDRE J; CLODFELTER KARL H; HAN BINGSONG; LIN JIAN; REYNOLDS DOMINIC J; SMITH CHASE C; WANG ZHONGGUO; ZHENG XIAOZHANG
    权利人:BAIR KENNETH W; BAUMEISTER TIMM; BUCKMELTER ALEXANDRE J; CLODFELTER KARL H; HAN BINGSONG; LIN JIAN; REYNOLDS DOMINIC J; SMITH CHASE C; WANG ZHONGGUO; ZHENG XIAOZHANG; FORMA TM LLC
    摘要:The present invention relates to compounds and composition for inhibition of NAMPT, their synthesis, applications and antidotes. An illustrative compound of the invention is shown below.

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    参考文献:10.1007/978-3-642-95940-0_8
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