CAS: 32884-36-9; Cajanin

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CAS号1100-15-8 5,7,2',4'-tetra... | CAS号621-23-8 1,3,5-三甲氧基苯 | CAS号6496-89-5 2,4-二甲氧基苯乙酸 | CAS号39604-69-8 2-hydroxy-4,6-d... | CAS号139445-84-4 (2,4-dimethoxy-... | CAS号521291-07-6 2-(2,4-dimethox... | CAS号98094-87-2 Lupinalbin A

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    📜1-(2'-Hydroxy-4',6'-Dimethoxyphenyl)-2-(2",4"-Dimethoxyphenyl)Ethanone置于三氯化硼体系中,用 二氯甲烷,甲苯 用作溶剂,化学反应生成木豆异黄酮
    参考文献:Apios异黄酮的全合成及其酪氨酸酶抑制活性的研究
    标题:Apios异黄酮的全合成及其酪氨酸酶抑制活性的研究
    摘要:通过friedel-Crafts反应,Bischler-Napieralski型环化和相转移催化糖基化作为关键步骤,首次合成了apios异黄酮葡萄糖苷1和2.此外,糖苷元4和5以及相关的天然异黄酮木豆素(6)可以在短时间内合成.这些化合物对酪氨酸酶的抑制活性的评估表明所有化合物都是有活性的.特别地,测得化合物1对酪氨酸酶的最大抑制浓度的一半为729μm.
    Doi:10.1016/j.Tet.2019.130589

    海关参考信息

    专利信息


    专利号:US-2007232495-A1
    优先权日:2006-03-24
    标题:Compositions and methods to add value to plant products, increasing the commercial quality, resistance to external factors and polyphenol content thereof
    发明人:NAPPA ALVARO O; LORENZINI FELIPE C; SANHUEZA ANDRES L
    权利人:NAPPA ALVARO O; LORENZINI FELIPE C; SANHUEZA ANDRES L
    摘要:The invention is related to compositions and methods that naturally protect plant tissues against ultraviolet radiation and temperature, thus giving protection against sunburn to plants, plant parts, fruits and/or flowers during their development. The invention is also related to compositions and methods to naturally improve the color of plants, plant parts, fruits and/or flowers by inducing the natural synthesis of flavonoids and anthocyanins present in plants. Likewise, the present invention is directed to improving the nutritional value of plants, plant parts, fruits and/or flowers by increasing the normal levels of polyphenolic compounds, especially flavonoids, present therein. Additionally, the present invention is related to compositions and methods that give more resistance to plants, plant parts, fruits and/or flowers against pathogens as bacteria and fungi. Finally, the present invention is related to plants, plant parts, fruits, flowers and/or propagating material treated with the compositions described in the present document.

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    主要参考文献


    1: Netcharoensirisuk P, Umehara K, De-Eknamkul W, Chaotham C. Cajanin Suppresses Melanin Synthesis through Modulating MITF in Human Melanin-Producing Cells. Molecules. 2021 Oct 5;26(19):6040. doi: 10.3390/molecules26196040.
    2: Tan S, Hua X, Xue Z, Ma J. Cajanin Stilbene Acid Inhibited Vancomycin- Resistant Enterococcus by Inhibiting Phosphotransferase System. Front Pharmacol. 2020 Apr 15;11:473. doi: 10.3389/fphar.2020.00473.
    3: Jia Y, Liu J, Yang Q, Zhang W, Efferth T, Liu S, Hua X. Cajanin stilbene acid: A direct inhibitor of colistin resistance protein MCR-1 that restores the efficacy of polymyxin B against resistant Gram-negative bacteria. Phytomedicine. 2023 Jun;114:154803. doi: 10.1016/j.phymed.2023.154803. Epub 2023 Apr 3. 23(16):9492. doi: 10.3390/ijms23169492.

    合成参考文献


    参考文献:10.1016/0305-1978(90)90006-2
    摘要:Ingham JL. Systematic aspects of phytoalexin formation within tribe Phaseoleae of the Leguminosae (subfamily Papilionoideae). Biochemical Systematics and Ecology. 1990 Aug;18(5):329–43. doi: 10.1016/0305-1978(90)90006-2.
    参考文献:10.1007/s10600-025-04755-7
    摘要:Chen D, Yuan Y, Li Z, Liu C, Aisa HA. Chemical Constituents from Leaves of Ficus carica and Their Antimicrobial Activity. Chem Nat Compd. 2025 Jul;61(4):770–2. doi: 10.1007/s10600-025-04755-7.
    参考文献:10.1080/14786410601086871
    摘要:Darbour N, Bayet C, Rodin-Bercion S, Elkhomsi Z, Lurel F, Chaboud A, Guilet D. Isoflavones fromFicus nymphaefolia. Natural Product Research. 2007 May;21(5):461–4. doi: 10.1080/14786410601086871.
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