CAS: 26652-09-5; 4-(2-(((1S,2R)-1-Hydroxy-1-(4-Hydroxyphenyl)Propan-2-yl)Amino)Ethyl)Phenol

上下游产品

Nitroethane p-benzyloxybenzaldehyde 2-[4-(benzyloxy)phenyl]acetaldehyde (1R,2S)-1-(4-benzyloxyphenyl)-2-[2-(4-benzyloxyphenyl)ethyl]amino-1-propanol

📜4-{(1S,2R)-2-[2-(4-Benzyloxy-Phenyl)-Ethylamino]-1-Hydroxy-Propyl}-Phenol; hydroChloride 在 Palladium On Activated Charcoal 氢气体系中,用 乙醇作为反应溶剂,获得 (+/-)-Ritodrine
参考文献:β-苯基乙胺衍生物x N-(羟基和甲氧基芳烷基)衍生物的合成† •
标题:β-苯基乙胺衍生物x N-(羟基和甲氧基芳烷基)衍生物的合成† •
摘要:描述了具有以下一般结构的化合物的合成和某些药理特性:
Doi:10.1002/Recl.19730921113

专利信息

专利号:WO-0112817-A1
优先权日:1999-08-12
标题:Evolution and use of enzymes for combinathorial and medicinal chemistry
发明人：KREBBER CLAUS; DAVIS S CHRISTOPHER; DELCARDAYRE STEPHEN; SELIFONOV SERGEY A; HOWARD RUSSELL
权利人:MAXYGEN INC; LIU LU; KREBBER CLAUS; DAVIS S CHRISTOPHER; DELCARDAYRE STEPHEN; SELIFONOV SERGEY A; HOWARD RUSSELL
摘要:This invention provides libraries of recombinant derivatizing enzymes that are useful for biocatalytic synthesis of derivatives oforganic molecules, including lead compounds for pharmaceutical use. The recombinant derivatizing enzymes catalyze reactions such as modification or replacement of functional groups on the organicmolecules, or addition of chemical moieties onto preexisting functional groups. The use of recombinant enzyme libraries enables one to obtain enzymes that catalyze the formation of organic molecule derivatives that could not otherwise be made using only naturally occurring enzymes.