CAS: 20945-53-3; (S)-2-(((Benzyloxy)Carbonyl)Amino)-3-(1H-Pyrazol-1-yl)Propanoic Acid
该化合物是一种乳胶氨酸衍生物,其成分为丙烯酸和丙苯受保护的矿物质组,其立体特性(S)可确保精确的手性,使其对不对称合成和peptide的修改具有价值.苯氧碳基(Cbz)组为胺提供正方位保护,从而能够在多步反应中有选择地去保护.pyrazol-1-ylpropanocial 环可增强它作为药用化学和Ingand设计中一个电子循环建筑块的效用.这种化合物因其结构多功能性以及与固态peptide合成的兼容性而特别有助于酶抑制剂,peptimetimic和生物活性探测器的发展.高纯度和定义的立体化学确保研究应用中的再生性.
- 英文名称(S)-2-(((Benzyloxy)Carbonyl)Amino)-3-(1H-Pyrazol-1-yl)Propanoic Acid
- 中文名称(S)-2-(((苄氧基)羰基)氨基)-3-(1H-吡唑-1-基)丙酸
- IUPAC名称(S)-2-(((benzyloxy)carbonyl)amino)-3-(1H-pyrazol-1-yl)propanoic acid
- 其它别名(S)-2-[(苄氧羰基)氨基]-3-(1H-吡唑-1-基)丙酸; Z-3-(Pyrazol-1-yl)-L-Ala-Oh
- CAS编号20945-53-3
- MFCD编号:MFCD10565756
- 分子式:C14H15N3O4分子量:289.29
- 产品CID: 1072522
- 产品分类有机原料→分子砌块→芳杂环类化合物→吡唑类化合物
相似化合物
2734-48-7 1217450-35-5 98632-92-9上下游产品
CAS号288-13-1 吡唑 | CAS号26054-60-4 N-苄氧羰基-L-丝氨酸(Β-内酯) | CAS号2734-48-7 (S)-2-氨基-3-(1-吡唑基)丙酸合成工艺路线路线简述
- 合成目标产物 L-N-Cbz-3-Pyrazol-1-Yl-Alanine 主要起始原料 Pyrazole And N-Carbobenzoxy-L-Serine Beta-Lactone
- (文献来源)合成步骤主要原料 Pyrazole 和 N-Carbobenzoxy-L-Serine Beta-Lactone
📜(S)-Benzyl 2-Oxooxetan-3-Ylcarbamate置于吡唑体系中,用 乙腈 用作溶剂,化学反应生成L-N-Cbz-3-吡唑-1-基-丙氨酸
参考文献:Hepatitis C Virus Inhibitors
标题:Hepatitis C Virus Inhibitors
摘要:本公开涉及化合物,组合物和治疗丙型肝炎病毒(hcv)感染的方法.还公开了含有这些化合物的药物组合物以及使用这些化合物治疗hcv感染的方法.
海关参考信息
- 2902300000-甲苯
2905121000-正丙醇
2906210000-苄醇
2912110000-甲醛 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:EP-1205471-A1
优先权日:2000-10-02
标题:A method of using synthetic L-SE-Methylselenocysteine as a nutriceutical and a method of its synthesis
发明人：SPALLHOLZ JULIAN E; REID TED W; WALKUP ROBERT D
权利人:PHARMASE INC
摘要:A synthesis of and use of L-Se-methylselenocysteine as a nutriceutical isndescribed, based upon the knowledge that L-Se-methylselenocysteine is lessntoxic than L-selenomethionine towards normal cells. The synthesis proceedsnby mixing N-(tert-butoxycarbonyl)-L-serine with a dialkyl diazodicarboxylatenand at least one of a trialkylphosphine, triarylphosphine and phosphite to formna first mixture that includes N-(tert-butoxycarbonyl)-L-serine β-lactone.nMethyl selenol or its salt is mixed with the N-(tert-butoxycarbonyl)-L-serine β-lactonento form a second mixture that includes N-(tert-butoxycarbonyl)-Se-methylselenocysteine.nThe text butoxycarbonyl group is removed from the N-(tert-butoxycarbonyl)-Se-methylselenocysteinento form L-Se-methylselenocysteine.nThis synthesis significantly improves thenmanufacturability, manufacturing efficiency and utility of this naturallynoccurring rare form of organic-selenium. L-Se-methylselenocysteine formed,nfor example, in this manner may be used as a nutriceutical for supplementationninto the diets of humans or animals for various beneficial purposes, such as, fornexample, to prevent or reduce the risk of developing cancer.
专利号:US-2003083383-A1
优先权日:1999-08-16
标 题:Method of using synthetic L-Se-methylselenocysteine as a nutriceutical and a method of its synthesis
