CAS: 1483-28-9; 2,5-Dimethoxybenzenesulfonyl Chloride

该化合物是一种有机化合物,其特点是,在一枚碳氢化合物的替代苯环上有一个附属于该环的全氟辛烷磺酰氯的有机体功能组,该化合物一般是白色到浅黄色的固体,以其反应性为名,特别是由于全氟辛基磺基氯组体的电益性,其代用反应的核糖代用品.二氧化硫组体增强了其在有机溶剂中的溶性,并能够影响其再活动性和稳定性.它通常被用作有机合成的试剂,特别是在制作磺酰胺和其他磺酰胺衍生物时.在处理该化合物时,必须采取安全防范措施,因为它可以是腐蚀性的,在接触水或水时可能会释放有毒气体.在冷干燥的地方适当储存,远离不相容的材料,对于保持其稳定性和防止降解至关重要.

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CAS号150-78-7 对苯二甲醚 | CAS号24920-40-9 2-butylsulfanyl... | CAS号19116-90-6 2,5-二甲氧基苯-1-磺胺 | CAS号1483-27-8 2,5-二甲氧基苯硫酚 | CAS号648956-96-1 4-butylsulfanyl... | CAS号496014-13-2 2,5-二甲氧基-N-3-喹啉-苯磺酰胺 | CAS号61638-04-8 1,4-二甲氧基-2-甲基硫代苯 | CAS号61638-05-9 1,4-dimethoxy-2...

合成工艺路线路线简述

    📜对苯二甲醚置于氯磺酸体系中,用68.3%的收率获得2,5-二甲氧基苯磺酰氯
    参考文献:磺酰肼和相关化合物.第十一部分.一些取代的芳基醚磺酰肼
    标题:磺酰肼和相关化合物.第十一部分.一些取代的芳基醚磺酰肼
    摘要:为了寻找新的害虫防治剂,制备了以下苯磺酰肼:5-氯-2-甲氧基-,3-氯-4-甲氧基-,2-氯-4-甲氧基,3-溴-4-甲氧基-,5-溴-2-甲氧基-,2-溴-4-甲氧基-,4-甲氧基-3-硝基-,3,4-二甲氧基-,2,5-二甲氧基-,2,4-二甲氧基-,3乙酰氨基-4-甲氧基,和5-乙酰氨基-2-甲氧基-,另外,4-ñ-Sulhonylhydrazinophenylacetic酸,和4-ñ-磺酰基肼基-2-甲氧基苯氧基乙酸已经制备.酰肼已被转化为许多衍生物(例如,酰肼,叠氮化物).
    Doi:10.1039/j39690001341

    海关参考信息

    专利信息


    专利号:US-7138526-B1
    优先权日:1999-06-15
    标 题 :Solid phase synthesis of n,n-disubstituted diazacycloalkylcarboxy derivatives
    发明人:HERPIN TIMOTHY F; MORTON GEORGE C; SALVINO JOSEPH M
    权利人:AVENTIS PHARMA INC
    摘要:A method for the solid phase synthesis of N,N-disubstituted diazacycloalkylcarboxy derivatives of general formula (I) and (II) is claimed. Examples include piperazine-2-carboxamide. The method is applicable to the synthesis or large combinatorial libraries

    专利号:US-8163773-B2
    优先权日:2005-07-11
    标题 :Organic compounds
    发明人:BREITENSTEIN WERNER; ERHARDT CLAUS; MAIBAUM JUERGEN KLAUS; OSTERMANN NILS; ZIMMERMANN JUERG; MASUYA KEIICHI; KONISHI KAZUHIDE; YOKOKAWA FUMIAKI; KANAZAWA TAKANORI; JACOBY EDGAR; MARZINZIK ANDREAS; GROSCHE PHILIPP; KAWAKAMI SHIMPEI
    权利人:BREITENSTEIN WERNER; ERHARDT CLAUS; MAIBAUM JUERGEN KLAUS; OSTERMANN NILS; ZIMMERMANN JUERG; MASUYA KEIICHI; KONISHI KAZUHIDE; YOKOKAWA FUMIAKI; KANAZAWA TAKANORI; JACOBY EDGAR; MARZINZIK ANDREAS; GROSCHE PHILIPP; KAWAKAMI SHIMPEI; NOVARTIS AG
    摘要:The invention relates to 3,5-substituted piperidine compounds, these compounds for use in the diagnostic and therapeutic treatment of a warm-blooded animal, especially for the treatment of a disease (=disorder) that depends on activity of renin; the use of a compound of that class for the preparation of a pharmaceutical formulation for the treatment of a disease that depends on activity of renin; the use of a compound of that class in the treatment of a disease that depends on activity of renin; pharmaceutical formulations comprising a 3,5-substituted piperidine compound, and/or a method of treatment comprising administering a 3,5-substituted piperidine compound, a method for the manufacture of a 3,5-substituted piperidine compound, and novel intermediates and partial steps for its synthesis. The preferred compounds (which can also be present as salts) have the formula I wherein R1, R2, T, R3 and R4 are as defined in the specification.

    专利号:JP-H1067724-A
    优先权日:1996-04-08
    标 题 :Resin for chemical synthesis having improved functional group and production of amide-based compound using the same

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    合成参考文献


    参考文献:10.1177/1087057116635503
    摘要:Voter AF, Manthei KA, Keck JL. A High-Throughput Screening Strategy to Identify Protein-Protein Interaction Inhibitors That Block the Fanconi Anemia DNA Repair Pathway. J Biomol Screen. 2016 Jul;21(6):626–33.
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