CAS: 950-81-2; 1,5-Dimethyl-3-Oxo-2-Phenyl-2,3-Dihydro-1H-Pyrazole-4-Carbaldehyde

该化合物是分子式C11H10N2O的有机化合物,其特点是,在四处放置的抗逆转录酶结构中有一个配有气态组(CHO),该物质是丙烯酮衍生物;该化合物一般是黄色至橙色晶状固体,在乙醇和丙酮等有机溶剂中溶解,但在水中溶解性有限. 4-四氟丙烯展示了各种化学特性,包括能够进行凝聚反应,使其在有机合成中有用,并作为其他化合物的中间体.此外,还对其潜在的生物活动进行了研究,包括抗炎和...

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相似化合物

83-10-3 60-80-0 56430-08-1

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

Antipyrinsaeurechlorid 61226-21-9
1-Phenyl-2,3-Dimethyl-4-Hydroxymethyl-Pyrazoline-5-On 10013-09-9
安替比林 Antipyrine 60-80-0
1,5-Dimethyl-2-Phenyl-4-(2,2,2-Trichloro-1-Hydroxy-Ethyl)-1,2-Dihydro-Pyrazol-3-One 66379-85-9

合成工艺路线路线简述

    📜安替比林置于n,N-二甲基甲酰胺,三氯氧磷体系中,化学反应生成 4-安替比林甲醛
    参考文献:Ito,Yakugaku Zasshi/journal Of The Pharmaceutical Society Of Japan,1956,Vol. 76,P. 167
    标题:Ito,Yakugaku Zasshi/journal Of The Pharmaceutical Society Of Japan,1956,Vol. 76,P. 167

    海关参考信息

    专利信息


    专利号:US-9574189-B2
    优先权日:2005-12-01
    标题:Enzymatic encoding methods for efficient synthesis of large libraries
    发明人:FRANCH THOMAS; LUNDORF MIKKEL DYBRO; JACOBSEN SØREN NYBOE; OLSEN EVA KAMPMANN; ANDERSEN ANNE LEE; HOLTMANN ANETTE; HANSEN ANDERS HOLM; SØRENSEN ANDERS MALLING; GOLDBECH ANNE; DE LEON DAEN; KALDOR DITTE KIEVSMOSE; SLØK FRANK ABILDGAARD; HUSEMOEN GITTE NYSTRUP; DOLBERG JOHANNES; Jensen Kim Birkebæ; PEDERSEN LENE; NØRREGAARD-MADSEN MADS; GODSKESEN MICHAEL ANDERS; GLAD SANNE SCHRØDER; NEVE SØREN; THISTED THOMAS; KRONBORG TINE TITILOLA AKINLEMINU; SAMS CHRISTIAN KLARNER; FELDING JAKOB; FRESKGÃ…RD PER-OLA; GOULIAEV ALEX HAAHR; PEDERSEN HENRIK
    权利人:FRANCH THOMAS; LUNDORF MIKKEL DYBRO; JACOBSEN SØREN NYBOE; OLSEN EVA KAMPMANN; ANDERSEN ANNE LEE; HOLTMANN ANETTE; HANSEN ANDERS HOLM; SØRENSEN ANDERS MALLING; GOLDBECH ANNE; DE LEON DAEN; KALDOR DITTE KIEVSMOSE; SLØK FRANK ABILDGAARD; HUSEMOEN GITTE NYSTRUP; DOLBERG JOHANNES; Jensen Kim Birkebæ; PEDERSEN LENE; NØRREGAARD-MADSEN MADS; GODSKESEN MICHAEL ANDERS; GLAD SANNE SCHRØDER; NEVE SØREN; THISTED THOMAS; KRONBORG TINE TITILOLA AKINLEMINU; SAMS CHRISTIAN KLARNER; FELDING JAKOB; FRESKGÃ…RD PER-OLA; GOULIAEV ALEX HAAHR; PEDERSEN HENRIK; NUEVOLUTION AS
    摘要:Disclosed is a method for obtaining a bifunctional complex comprising a molecule linked to a single stranded identifier oligonucleotide, wherein a nascent bifunctional complex comprising a chemical reaction site and a priming site for enzymatic addition of a tag is a) reacted at the chemical reaction site with one or more reactants, and b) reacted enzymatically at the priming site with one or more tag(s) identifying the reactant(s).

    专利号:US-11225655-B2
    优先权日:2010-04-16
    标题:Bi-functional complexes and methods for making and using such complexes
    发明人:GOULIAEV ALEX HAAHR; FRANCH THOMAS; GODSKESEN MICHAEL ANDERS; JENSEN KIM BIRKEBAEK
    权利人:GOULIAEV ALEX HAAHR; FRANCH THOMAS; GODSKESEN MICHAEL ANDERS; JENSEN KIM BIRKEBAEK; NUEVOLUTION AS
    摘要:The present invention is directed to a method for the synthesis of a bi-functional complex comprising a molecule part and an identifier oligonucleotide part identifying the molecule part. A part of the synthesis method according to the present invention is preferably conducted in one or more organic solvents when a nascent bi-functional complex comprising an optionally protected tag or oligonucleotide identifier is linked to a solid support, and another part of the synthesis method is preferably conducted under conditions suitable for enzymatic addition of an oligonucleotide tag to a nascent bi-functional complex in solution.

    专利号:US-11702652-B2
    优先权日:2005-12-01
    标题:Enzymatic encoding methods for efficient synthesis of large libraries

    专利号:US-2009264300-A1
    优先权日:2005-12-01
    标题 :Enzymatic encoding methods for efficient synthesis of large libraries

    专利号:US-2020216836-A1
    优先权日:2005-12-01
    标题 :Enzymatic encoding methods for efficient synthesis of large libraries

    专利号:EP-1957644-B1
    优先权日:2005-12-01
    标 题 :Enzymatic encoding methods for efficient synthesis of large libraries

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    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    摘要:Sapeta, K.; Kerr, M. A., Science of Synthesis Knowledge Updates, (2011) 1, 43.
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