CAS: 7729-23-9; Methyl (E)-2-[(2S,3R,12Br)-3-Ethyl-1,2,3,4,6,7,12,12B-Octahydroindolo[2,3-A]Quinolizin-2-Yl]-3-Methoxyprop-2-Enoate

上下游产品

diazomethane dimethyl sulfate methanol 2-((2R,3S,12bS)-3-Ethyl-1,2,3,4,6,7,12,12b-°Ctahydro-indolo[2,3-a]quinolizin-2-yl)-3-oxo-propionic acid methyl ester

专利信息

专利号:US-12378584-B2
优先权日:2018-06-13
标 题 :Methionine analogue synthesis
发明人：WILTSCHI BIRGIT; FLADISCHER PATRIK; OFFNER-MARKO LISA-RAMONA; HECKENBICHLER KATHRIN; BREINBAUER ROLF
权利人:ENGENES BIOTECH GMBH
摘要:The present invention relates to a method for preparing a methionine analogue, comprising contacting a host cell with L-homoserine and one or more nucleophiles and cultivating said host cell and said one or more nucleophiles of (a) in a fermentation broth to produce said methionine analogue, wherein said host cell encodes and stably expresses a L-homoserine-O-acetyl-transferase (HSAT) and an O-acetyl-L-homoserine sulfhydrylase (OAHS). The present invention also relates to host cells encoding and expressing such HSAT and OAHS, as well as uses thereof for producing a methionine analogue.

专利号:CN-118557544-A
优先权日:2024-04-19
标 题:General synthesis method and application of high-permeability nano drug-carrying system