CAS: 68194-11-6; 2,3,4',5,6-Pentachloro-1,1'-Biphenyl
该化合物是多氯联苯(PCB)家族的成员,这些合成有机化学品以其环境持久性和潜在毒性而著称,该化合物由两个相连的苯环组成,其中五个氯原子在双苯结构的特定位置被替换为五氯原子,多种氯原子的存在增强了其疏水性和亲脂性,导致活生物体中的生物累积性,并可能导致食物链中的生物放大作用. 2,3,4',5,6-五氯苯的特点是其稳定性和耐降解性,因此引起对环境污染的关注,它与各种不良健康影响有关,包括内分泌干扰和致癌性.由于这些特性,许多国家对多氯联苯的使用进行了严格的管制或禁止.在环境样品中,通常使用诸如气色谱-质谱仪等分析方法来检测和量化这种化合物.
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- 产品信息参考
;;;; - InChIKey: ZDDZPDTVCZLFFC-UHFFFAOYSA-N
- 1S/C12H5Cl5/c13-7-3-1-6(2-4-7)10-11(16)8(14)5-9(15)12(10)17/h1-5H
- 计算化学: 氢键受体数*氢键供体数0可旋转键数1
MSDS等安全信息
- GHS符号GHS07
- 警示词Warning
- 危险描述H302-H315-H319-H335
- 防范说明P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
- 安全声明The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcription of genes, mainly be inducing the expression of hepatic Phase I and Phase II enzymes, especially of the cytochrome P450 family. Most of the toxic effects of PCBs are believed to be results of Ah receptor binding. Other PBCs are believed to interfere with calcium channels and/or change brain dopamine levels. PCBs can also cause endocrine disurption by altering the production of thyroid hormones and binding to estrogen receptors, which can stimulate the growth of certain cancer cells and produce other estrogenic effects, such as reproductive dysfunction. They will bioaccumulate by binding to receptor proteins such as uteroglobin. (A3, A4, A30, A66)
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1-Chloro-4-iodobenzene 1,2,4,5-Tetrachloro-3-iodobenzene合成工艺路线路线简述
海关参考信息
- 2903911000-邻二氯苯
- 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
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供应商参考报价(招募中)
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📌 第三方产品分析报告
合成参考文献
摘要:T14: Lewis RJ (1996). Sax's Dangerous Properties of Industrial Materials. 9th ed. Volumes 1-3. New York, NY: Van Nostrand Reinhold.
摘要:L4: ATSDR - Agency for Toxic Substances and Disease Registry (2000). Toxicological profile for polychlorinated biphenyls. U.S. Public Health Service in collaboration with U.S. Environmental Protection Agency (EPA).
摘要:L134: ATSDR - Agency for Toxic Substances and Disease Registry (2001). Minimal Risk Levels (MRLs) for Hazardous Substances. U.S. Public Health Service in collaboration with U.S. Environmental Protection Agency (EPA).
摘要:L135: International Agency for Research on Cancer (2014). IARC Monographs on the Evaluation of Carcinogenic Risks to Humans.
摘要:T6: World Health Organization (1993). Environ Health Criteria 140: Polychlorniated Biphenyls and Terphenyls.
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